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The Microbiome: Past, Present, and Future
Pages 3-11
This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms in autoimmunity and the deeply related rheumatic diseases. This book comprehensively explains the emerging microbiome research through the interrelationships of biomedical sciences, including: immunology, microbiology, bioinformatics, and, with special emphasis, the clinical aspect of rheumatology. It examines the interplay between infectious organisms and major autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile arthritis, systemic lupus erythematosus, and vasculitis, and explains how to apply that knowledge to diagnostic techniques and treatment decisions. The international team of expert authors provides insight into current therapies and future interventions specifically targeting the microbiota and explores the impact of our deeper understanding on enhancing personalized medicine. The Microbiome in Rheumatic Diseases and Infection is an essential resource for rheumatologists, pediatricians, internists, microbiologists, and critical care providers caring for children and adults with rheumatic diseases.
The Microbiome: Past, Present, and Future
Pages 3-11
Methods for Microbiota Analysis: Sample Collection and Laboratory Methods
Pages 13-27
Analytic Methods in Microbiome Studies
Pages 29-42
Immunodeficiency and Autoimmunity
Pages 45-54
Immunology of the Microbiome: Implications for Rheumatoid Arthritis and Other Autoimmune Diseases
Pages 55-62
Animal Models of Rheumatoid Arthritis
Pages 63-72
Lyme Disease: Infectious and Noninfectious Features
Pages 75-85
Helicobacter pylori: Immune Responses and Gastric Autoimmunity
Pages 87-96
Rheumatic Complications of Streptococcus pyogenes
Pages 97-102
Mollicutes: Mycoplasma pneumoniae
Pages 103-111
DNA Viruses in Autoimmune Rheumatic Diseases
Pages 113-127
RNA Viruses and Autoimmunity: A Short Overview
Pages 129-138
Autoimmunity and the Paradox of Chagas Disease
Pages 139-147
Macrophage Activation Syndrome
Pages 151-182
Rheumatoid Arthritis
Pages 183-199
Spondyloarthritis
Pages 201-220
Juvenile Idiopathic Arthritis
Pages 221-237
Psoriasis and Psoriatic Arthritis
Pages 239-250
Inflammatory Bowel Disease
Pages 251-274
Reactive Arthritis
Pages 275-284
Systemic Lupus Erythematosus
Pages 285-304
Antiphospholipid Syndrome
Pages 305-321
Sjögren’s Syndrome
Pages 323-335
Systemic Sclerosis
Pages 337-346
Systemic Vasculitides
Pages 347-353
Cryoglobulinemic Vasculitis
Pages 355-363
Behçet Disease
Pages 365-370
Autoinflammatory Diseases
Pages 371-377
Histiocytoses
Pages 379-390
Subacute Bacterial Endocarditis
Pages 391-401
Chronic Recurrent Multifocal Osteomyelitis (CRMO)
Pages 403-408
Vaccinations in Rheumatology
Pages 411-426
Management of Autoimmune and Inflammatory Disorders in the Setting of Infection or Immunodeficiency
Pages 427-443
Individual Drugs in Rheumatology and the Risk of Infection
Pages 445-464
The Promise of Personalized Medicine
Pages 465-474
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