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The Harriet Lane Handbook of Pediatric Antimicrobial Therapy, 2nd Edition
McMillan, Lee, Siberry, Carroll
20,00 €
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From the experts at Johns Hopkins University who bring you the bestselling Harriet Lane Handbook, the Harriet Lane Handbook of Pediatric Antimicrobial Therapy delivers quick, dependable answers to help you effectively treat a broad spectrum of pediatric infectious diseases. This highly regarded medical reference book is your pocket-sized source for all of the evidence-based recommendations you need to provide the best possible care to your young patients.

New to this edition
  • Make the best clinical decisions with up-to-date practice guidelines from the AAP, CDC, and other authoritative pediatric and infectious disease sources.
  • Stay on top of the most effective treatments with leading-edge coverage of antiretroviral drugs for HIV and hepatitis; antimicrobial pharmacokinetic/pharmacodynamics (PK/PD) information; the latest Vancomycin therapeutic drug-monitoring recommendations; antimicrobial desensitization; pediatric developmental effects of antimicrobials approved in adults but not children; and much more.
  • Depend on the professional wisdom of an expert author team, combined with the front-line input of current pediatric infectious disease fellows.
  • Access the fully searchable text online at Expert Consult.
Author Info
By Julia McMillan, MD, Director, Residency Program, Vice Chair for Pediatric Education, Professor, Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD; Carlton K. Lee, PharmD, MPH, Assistant Professor and Clinical Coordinator, Pediatrics, Department of Pharmacy, Johns Hopkins Hospital, Baltimor, MD; George K. Siberry, MD, MHP, Co-Chair, Infection Control, Krieger Institute, Assistant Professor of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD and Karen Carroll, MD


Table of Contents:


Notes and Abbreviations Used in Tables

1. Infectious Agents and Drugs of Choice

I. Recommended Treatment for Bacterial Infections

II. Recommended Treatment for Mycobacterial Infections

III. Recommended Treatment for Viral Infections

IV. Recommended Treatment for Fungal Infections

V. Recommended Treatment for Parasitic and Protozoal Infections

2. Recommended Empiric Antimicrobial Therapy for Selected Clinical Syndromes

3. Drug Dosing in Special Circumstances

4. Mechanisms of Action and Routes of Administration of Antimicrobial Agents

5. Mechanisms of Drug Resistance

I. Common Mechanisms of Microbial Resistance

II. Discordance Between in Vitro Susceptibility and in Vivo Efficacy

6. Therapeutic Drug Monitoring

I. General Principles

II. Antimicrobials Requiring Therapeutic Drug Monitoring

III. Special Topics in Antimicrobial Therapeutic Drug Monitoring

IV. Pharmacokinetic Monitoring in Therapeutic Drug Monitoring

V. Pharmacokinetic/Pharmacodynamic (PK/PD) Antimicrobial Relationships

VI. Drug Interactions

7. Adverse Drug Reactions

I. Blood

II. Cardiovascular

III. Central Nervous System

IV. Skin

V. Gastrointestinal


VII. Renal/Genitourinary

VIII. Respiratory

IX. Hepatic

X. Ocular

XI. Musculoskeletal

XII. Hypersensitivity

XIII. Other

8. Recommended Antimicrobial Prophylaxis for Selected Infectious Agents and Conditions

9. Antimicrobial Desensitization Protocols

I. Penicillin

II. Amoxicillin

III. Cephalosporins

IV. Trimethoprim/Sulfamethoxazole (TMP/SMX) Oral

V. Fluoroquinolone

VI. Vancomycin

VII. Aminoglycosides

VIII. Clindamycin

IX. Linezolid

X. Darunavir

10. Formulary


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