Table of Contents:

CONTENTS

Notes and Abbreviations Used in Tables

1. Infectious Agents and Drugs of Choice

I. Recommended Treatment for Bacterial Infections

II. Recommended Treatment for Mycobacterial Infections

III. Recommended Treatment for Viral Infections

IV. Recommended Treatment for Fungal Infections

V. Recommended Treatment for Parasitic and Protozoal Infections

2. Recommended Empiric Antimicrobial Therapy for Selected Clinical Syndromes

3. Drug Dosing in Special Circumstances

4. Mechanisms of Action and Routes of Administration of Antimicrobial Agents

5. Mechanisms of Drug Resistance

I. Common Mechanisms of Microbial Resistance

II. Discordance Between in Vitro Susceptibility and in Vivo Efficacy

6. Therapeutic Drug Monitoring

I. General Principles

II. Antimicrobials Requiring Therapeutic Drug Monitoring

III. Special Topics in Antimicrobial Therapeutic Drug Monitoring

IV. Pharmacokinetic Monitoring in Therapeutic Drug Monitoring

V. Pharmacokinetic/Pharmacodynamic (PK/PD) Antimicrobial Relationships

VI. Drug Interactions

7. Adverse Drug Reactions

I. Blood

II. Cardiovascular

III. Central Nervous System

IV. Skin

V. Gastrointestinal

VI. Endocrine/METABOLIC

VII. Renal/Genitourinary

VIII. Respiratory

IX. Hepatic

X. Ocular

XI. Musculoskeletal

XII. Hypersensitivity

XIII. Other

8. Recommended Antimicrobial Prophylaxis for Selected Infectious Agents and Conditions

9. Antimicrobial Desensitization Protocols

I. Penicillin

II. Amoxicillin

III. Cephalosporins

IV. Trimethoprim/Sulfamethoxazole (TMP/SMX) Oral

V. Fluoroquinolone

VI. Vancomycin

VII. Aminoglycosides

VIII. Clindamycin

IX. Linezolid

X. Darunavir

10. Formulary