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Textbook of Penile Cancer reports accurately on recent developments in the management of penile cancer, whilst also covering the fundamentals of the disease, to provide a comprehensive, stand-alone and up-to-date volume on the subject.
The surgical management of penile cancer is shifting towards increasingly refined methods, as it is believed that a proportion of patients undergo overtreatment for the disease. Where traditionally the management of penile cancer has involved partial or total penectomy combined with radical inguinal lymphadenectomy, over the last few years the treatment involves conservative penile reconstructive surgery such that sexual function and phallic length is preserved. Furthermore, the increasing utilization of sentinel lymph node biopsy rather than radical inguinal lymphadenectomy prevents the unnecessary removal of lymph nodes in patients where lymph node metastases has not occurred. There is also likely to be a change in the role of chemotherapy and radiotherapy for advanced disease.
Textbook of Penile Cancer covers the epidemiology, molecular biology, radiological imaging, as well as the latest surgical advances in the treatment of this disease. This book is a valuable reference tool for Urological Surgeons, Genitourinary Physicians, Trainee Surgeons, Plastic Surgeons, Oncologists, Dermatologists and Sexual Health Physicians.
xiii
Contents
1 Epidemiology and Etiology of Penile Cancer . . . . . . . . . . . . . . . . . . . 1
Maaike C.G. Bleeker, Daniëlle A.M. Heideman, Peter J.F. Snijders,
Simon Horenblas, and Chris J.L.M. Meijer
2 Molecular Biology of Penile Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Daniëlle A.M. Heideman, Maaike C.G. Bleeker,
Hashim Uddin Ahmed, Manit Arya, Simon Horenblas,
Peter J.F. Snijders, and Chris J.L.M. Meijer
3 Diagnosis and Pathology of Penile Cancer . . . . . . . . . . . . . . . . . . . . 27
Alcides Chaux and Antonio L. Cubilla
4 Radiological Imaging in Penile Cancer . . . . . . . . . . . . . . . . . . . . . . . . 69
Alex P.S. Kirkham
5 Premalignant Lesions of the Penis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103
Majid Shabbir, Nicholas A. Watkin, and Asif Muneer
6 Management of Penile Cancer Using
Penile-Preserving Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125
Paul Hadway, Peter R. Malone, Suks Minhas, and Asif Muneer
7 Management of Locally Advanced
and Metastatic Penile Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143
Asif Muneer, Afshin Mosahebi, Vijay Sangar, and Suks Minhas
8 Cancer of the Male Urethra . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167
Raj Nigam, Usama Ahmed, Alex Freeman, Suks Minhas,
and Asif Muneer
9 Management of Lymph Nodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 183
Niels M. Graafl and and Simon Horenblas
10 Prognostic Indicators in Penile Cancer . . . . . . . . . . . . . . . . . . . . . . . . 215
Vincenzo Ficarra, Giacomo Novara, Guido Martignoni,
and Filiberto Zattoni
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11 Phallic Reconstruction Following
Surgery for Penile Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 237
David J. Ralph
12 The Role of Chemotherapy and Radiotherapy
in the Treatment of Penile Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . 259
Jan M. Kerst, Luc M.F. Moonen, Niels M. Graafl and,
Andries M. Bergman, Floris J. Pos, and Simon Horenblas
13 Nanotechnology and the Implications for Penile Cancer . . . . . . . . . . 273
Ammar Hameed, Iqbal S. Shergill, and Manit Arya
14 Follow-Up of Patients with Penile Cancer . . . . . . . . . . . . . . . . . . . . . . 283
Niels M. Graafl and and Simon Horenblas
15 Living with Penile Cancer: Effects on
Psychology and Quality of Life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 291
Ian Eardley and Victor Palit
16 Future Directions in Penile Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . 301
Paul K. Hegarty and Curtis A. Pettaway
Appendix. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 319
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 325
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