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Ocular Disease: Mechanisms and Management
Levin, Albert
110,00 €
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Ocular Disease-a newly introduced companion volume to the classic Adler’s Physiology of the Eye-correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert-two of the world’s leading ophthalmic clinician-scientists-have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color-with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. In print and online at, this comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment.

Author Info
By Leonard A Levin, MD, PhD, Canada Research Chair of Ophthalmology and Visual Sciences, Univerisity of Montreal, Montreal, Quebec, Canada; Professor of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA and Daniel M. Albert, MD, MS, RRF Emmett A. Humble Distinguished Director of the UW Eye Research Institute; F.A Davis Professor and Chair Emeritus, Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.


Table of Contents:

SECTION 1 Cornea

1. Loss of corneal transparency

Russell L McCally

2. Abnormalities of corneal wound healing

Audrey M Bernstein

3. Wound healing after laser in situ keratomileusis and photorefractive keratectomy

Fabricio Witzel de Medeiros and Steven E Wilson

4. Genetics and mechanisms of hereditary corneal dystrophies

John D Gottsch

5. Fuchs’ endothelial corneal dystrophy

Vinay Gutti, David S Bardenstein, Sudha Iyengar, and Jonathan H Lass

6. Keratoconus

M Cristina Kenney and Ronald N Gaster

7. Infectious keratitis

Michael S Gilmore, Susan R Heimer, and Ai Yamada

8. Corneal graft rejection

Daniel R Saban, Mohammad H Dastjerdi, and Reza Dana

9. Corneal edema

Daniel G Dawson and Henry F Edelhauser

10. Corneal angiogenesis and lymphangiogenesis

Chih-Wei Wu, David Ellenberg, and Jin-Hong Chang

11. Ocular surface restoration

Julie T Daniels, Genevieve A Secker, and Alex J Shortt

12. Herpetic keratitis

Pranita P Sarangi and Barry T Rouse

13. Ocular allergy

Neal P Barney, Ellen B Cook, James L Stahl, and Frank M Graziano


SECTION 2 Dry eye

14. The lacrimal gland and dry-eye disease

Darlene A Dartt

15. Immune mechanisms of dry-eye disease

Austin K Mircheff and Joel E Schechter

16. Disruption of tear film and blink dynamics

Jianhua Wang and Anuj Chauhan

17. Abnormalities of eyelid and tear film lipid

Gary N Foulks and Douglas Borchman

18 Dry eye: abnormalities of tear film mucins

Ann-Christin Albertsmeyer and Ilene K Gipson


SECTION 3 Glaucoma

19. Steroid-induced glaucoma

Abbot F Clark, Xinyu Zhang, and Thomas Yorio

20. Biomechanical changes of the optic disc

Ian A Sigal, Michael D Roberts, Michael JA Girard, Claude F Burgoyne, and J Crawford Downs

21. Pigmentary dispersion syndrome and glaucoma

Michael G Anderson

22. Abnormal trabecular meshwork outflow

Paul A Knepper and Beatrice YJT Yue

23. Pressure-induced optic nerve damage

James C Tsai

24. Exfoliation (pseudoexfoliation) syndrome

Robert Ritch and Ursula Schlötzer-Schrehardt

25. Angle closure glaucoma

Shamira Perera, Nishani Amerasinghe, and Tin Aung

26. Central nervous system changes in glaucoma

Yeni N Yücel and Neeru Gupta

27. Retinal ganglion cell death in glaucoma

Heather R Pelzel and Robert W Nickells

28. Wound-healing responses to glaucoma surgery

Stelios Georgoulas, Annegret Dahlmann-Noor, Stephen Brocchini, and Peng Tee Khaw

29. Blood flowchanges in glaucoma

Leopold Schmetterer and Mark Lesk



30. Biochemical mechanisms of age-related cataract

David C Beebe, Ying-Bo Shui, and Nancy M Holekamp

31. Posterior capsule opacification

Judith West-Mays and Heather Sheardown

32. Diabetes-associated cataracts

Peter F Kador

33. Steroid-induced cataract

Abbas Samadi

34. Presbyopia

Jane F Koretz

35. Restoration of accommodation

Stephen D McLeod and Michelle Trager Cabrera

36. Intraoperative floppy iris syndrome

Amy Lin and Roger F Steinert


SECTION 5 Neuro-ophthalmology

37. Optic neuritis

John R Guy and Xiaoping Qi

38. Abnormal ocular motor control

James A Sharpe and Arun Sundaram

39. Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri)

Deborah M Grzybowski and Martin Lubow

40. Giant cell arteritis

Lynn K Gordon

41. Ischemic optic neuropathy

Helen Danesh-Meyer

42. Optic nerve axonal injury

Daniela Toffoli and Leonard A Levin

43. Leber’s hereditary optic neuropathy

Alfredo Sadun and Alice Kim

44. Optic atrophy

Nathan T Tagg and Randy H Kardon

45. Nystagmus

Frank Proudlock and Irene Gottlob

46. Toxic optic nerve neuropathies

FT "Fritz" Fraunfelder and FW "Rick" Fraunfelder


SECTION 6 Oncology

47. Uveal melanoma

Zélia MS Corrêa and J William Harbour

48. Genetics of hereditary retinoblastoma

Alejandra G de Alba Campomanes and Joan M O’Brien

49. Molecular basis of low-penetrance retinoblastoma

Katie Matatall and J William Harbour

50. Vasculogenic mimicry

Robert Folberg and Andrew J Maniotis

51. Treatment of choroidal melanoma

Aimee V Chappelow and Andrew P Schachat

52. Sebaceous cell carcinoma

Alon Kahana, Jonathan T Pribila, Christine C Nelson, and Victor M Elner

53. Neurofibromatosis

Robert Listernick and David H Gutmann



54 Phthisis bulbi

Ingo Schmack, Hans E Völcker, and Hans E Grossniklaus

55. Myopia

Terri L Young

56. Pathogenesis of Graves’ ophthalmopathy

A Reagan Schiefer and Rebecca S Bahn


SECTION 8 Pediatrics

57. Duane syndrome

Joseph L Demer

58. Amblyopia

Robert F Hess and Nigel Daw

59 Strabismus

Christopher S von Bartheld, Scott A Croes, and L Alan Johnson

60. Albinism

Gerald F Cox and Anne B Fulton

61. Aniridia

Elias I Traboulsi


SECTION 9 Retina

62. Color vision defects

Maureen Neitz and Jay Neitz

63. Acute retinal vascular occlusive disorders

Sohan Singh Hayreh

64. Retinal photic injury: laboratory and clinical findings

Daniel Organisciak and Marco Zarbin

65. Vascular damage in diabetic retinopathy

Timothy S Kern and Suber Huang

66. Neovascularization in diabetic retinopathy

Corey B Westerfeld and Joan W Miller

67. Diabetic macular edema

Pascale Massin, Michel Paques, and Jean-Antoine Pournaras

68. Dry age-related macular degeneration and age-related macular degeneration pathogenesis

Marco Zarbin and Janet S Sunness

69. Neovascular age-related macular degenerationDavid E Lederer, Scott W Cousins, and Karl G Csaky

70. Inhibition of

Anthony P Adamis and Adrienne Berman

71. Retinal detachment

Steven K Fisher and Geoffrey P Lewis

72. Retinopathy of prematurity

Mary Elizabeth Hartnett and Cynthia A Toth

73. Retinal energy metabolism

Robert A Linsenmeier

74. Retinitis pigmentosa and related disorders

Eric A Pierce

75 Visual prostheses and other assistive devices

Muhammad Ali Memon and Joseph F Rizzo III

76. Paraneoplastic retinal degeneration

Grazyna Adamus

77. Cellular repopulation of the retina

Budd AL Tucker, Michael J Young, and Henry J Klassen

78. Proliferative vitreoretinopathy

Clyde Guidry


SECTION 10 Uveitis

79. Immunologic mechanisms of uveitis

Steven Yeh, Zhuqing Li, and Robert B Nussenblatt

80. Herpesvirus retinitis

Sally S Atherton and Mei Zheng

81. Sympathetic ophthalmia

Mirunalini Kumaradas and Narsing A Rao

82. Scleritis

Srilakshmi M Sharma and James T Rosenbaum

83 Infectious uveitis

Pooja Bhat, Allen Tony Jackson, and C Stephen Foster

84. Ocular sarcoidosis

Russell N Van Gelder and Suzanne M Dintzis




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