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Introduction: Retina Imaging—Past and Present
Pages 1-5
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models.
Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.
Introduction: Retina Imaging—Past and Present
Pages 1-5
OCT Technique: Past, Present and Future
Pages 7-31
The APOSTEL Recommendations
Pages 33-39
OCT Angiography: Guidelines for Analysis and Interpretation
Pages 41-54
Seeing the Brain Through the Eye: What Is Next for Neuroimaging and Neurology Applications
Pages 55-82
Advances in Retinal Imaging: Retinal Amyloid Imaging
Pages 83-122
Advances in Retinal Imaging: Real-Time Imaging of Single Neuronal Cell Apoptosis (DARC)
Pages 123-138
Retinal Oximetry in Central Nervous System Diseases
Pages 139-145
Optical Coherence Tomography and Optic Nerve Edema
Pages 147-167
OCT and Compressive Optic Neuropathy
Pages 169-194
OCT and Multiple Sclerosis
Pages 195-233
OCT in Parkinson’s Disease and Related Disorders
Pages 235-262
Optical Coherence Tomography in Alzheimer’s Disease
Pages 263-288
Friedreich’s Ataxia and More: Optical Coherence Tomography Findings in Rare Neurological Syndromes
Pages 289-316
Other Neurological Disorders: Migraine, Neurosarcoidosis, Schizophrenia, Obstructive Sleep Apnea-Hypopnea Syndrome and Bipolar Disorder
Pages 317-342
Hereditary Optic Neuropathies
Pages 343-364
Trans Neuronal Retrograde Degeneration to OCT in Central Nervous System Diseases
Pages 365-374
OCT in Toxic and Nutritional Optic Neuropathies
Pages 375-400
Animal Models in Neuro Ophthalmology
Pages 401-426
OCT in Glaucoma
Pages 427-472
OCT in Amblyopia
Pages 473-485
Pediatric Neuro-Ophthalmology and OCT
Pages 487-505
Machine Learning Approaches in OCT: Application to Neurodegenerative Disorders
Pages 507-521
Optical Coherence Tomography Angiography in Neurology and Neuro-Ophthalmology
Pages 523-544
Conclusion: The Exciting Future of OCT and New Imaging of Retina and Optic Nerve
Pages 545-547
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