Chapter 1 The Hematopoietic System and Hematopoiesis
Christopher Y. Park and Michael G. Kharas

Chapter 2 The Immune System
Andrea Cerutti, Giuliana Magri, Montserrat Cols, Linda Cassis, Cindy Gutzeit, Alejo Chorny, Maurizio Gentile, Carolina M. Barra, and Irene Puga

Chapter 3 Immunophenotypic Markers Useful in the Diagnosis and Classification of Hematopoietic and Lymphoid Neoplasms
Kate E. Grimm, Todd S. Barry, Dennis P. O’Malley, and Lawrence M. Weiss

Chapter 4 Flow Cytometry in the Assessment of Hematologic Disorders
Kaaren K. Reichard and Steven H. Kroft

Chapter 5 Normal Histology of the Lymphoid Tissues
J. Han van Krieken

Chapter 6 Antigen Receptor Genes: Structure, Function, and Molecular Analysis in Clinical Applications
Y. Lynn Wang, Ethel Cesarman, and Daniel M. Knowles

Chapter 7 Protooncogenes and Tumor Suppressor Genes in Hematopoietic Malignancies
Wayne Tam and Laura Pasqualucci

Chapter 8 Application of Molecular Genetics to the Diagnosis and Classification of Hematologic Neoplasms
Christopher David Watt, Michele Renee Roullet, and Adam Bagg

Chapter 9 Role of Cytogenetic Analysis in the Diagnosis and Classification of Hematopoietic Neoplasms
Karen J. Ouyang and Michelle M. Le Beau

Chapter 10 Organization and Operation of a Hematopathology Laboratory
Wayne Tam, Angela R. Murray, Attilio Orazi, and Daniel M. Knowles

Chapter 11 Technical Factors in the Preparation and Evaluation of Lymph Node Biopsies
Sonam Prakash and Peter M. Banks

Chapter 12 The Role of Fine Needle Aspiration Biopsy in the Diagnosis and Management of Hematopoietic Neoplasms
Rana S. Hoda

Chapter 13 Benign and Reactive Conditions of Lymph Nodes and Related Organs
Kate E. Grimm and Dennis P. O’Malley

Chapter 14 Atypical Lymphoproliferative Disorders
Dennis P. O’Malley and Kate E. Grimm

Chapter 15 Hodgkin Lymphoma: Histopathology and Differential Diagnosis
Jerome S. Burke

Chapter 16 Hodgkin Lymphoma: Cell of Origin, Immunobiology, and Pathogenesis
Ralf Küppers, Sylvia Hartmann, and Martin-Leo Hansmann

Chapter 17 Classification of Non-Hodgkin Lymphomas
Lawrence M. Weiss and Karen L. Chang

Chapter 18 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and B-cell Prolymphocytic Leukemia
David Czuchlewski and Kathryn Foucar

Chapter 19 Lymphoplasmacytic Lymphoma
Michiel van den Brand and J. Han van Krieken

Chapter 20 Mantle Cell Lymphoma
James R. Cook and Steven H. Swerdlow

Chapter 21 Nodal Marginal Zone B-Cell Lymphoma
Alexandra Traverse-Glehen and Françoise Berger

Chapter 22 Follicular Lymphoma
Grant Nybakken, Roger Warnke, and Yasodha Natkunam

Chapter 23 Diffuse Large B-Cell Lymphoma
Ken H. Young, L. Jeffrey Medeiros, and Wing C. Chan

Chapter 24 Burkitt Lymphoma and Related Disorders
Philip M. Kluin and Stefano Rosati

Chapter 25 Lymphadenopathy and the Lymphoid Neoplasms Associated with HIV Infection and Other Causes of Immunosuppression
Jonathan Said, Ethel Cesarman, and Daniel M. Knowles

Chapter 26 Peripheral T-cell Lymphomas
Andrew L. Feldman and Ahmet Dogan

Chapter 27 Nonhematopoietic Elements in Lymph Nodes
Julia Turbiner Geyer and Daniel M. Knowles

Chapter 28 Extranodal Lymphoid Proliferations: General Principles
Jerome S. Burke

Chapter 29 Benign and Malignant Cutaneous Lymphoproliferative Disorders Including Mycosis Fungoides
Cynthia Magro

Chapter 30 Gastrointestinal Lymphomas and Lymphoid Hyperplasias
Ming-Qing Du and Andrew C. Wotherspoon

Chapter 31 Hematolymphoid Lesions of the Lung and Pleura
Gerald J. Berry

Chapter 32 Malignant Lymphomas and Lymphoid Hyperplasias That Occur in the Ocular Adnexa (Orbit, Conjunctiva, and Eyelids)
Julia Turbiner Geyer and Daniel M. Knowles

Chapter 33 Extranodal Lymphomas and Lymphoid Hyperplasias of the Waldeyer’s Ring, Sinonasal Region, Salivary Gland, Thyroid Gland, Central Nervous System, and Other Less Common Sites
Jerome S. Burke

Chapter 34 Bone Marrow Specimen Procurement and Processing
Yi-Hua Chen and LoAnn Peterson

Chapter 35 Bone Marrow Manifestations of Hodgkin and Non-Hodgkin Lymphomas and Lymphoma-Like Disorders
Beverly P. Nelson and LoAnn Peterson

Chapter 36 Hairy Cell Leukemia and Related Disorders
Qian-Yun Zhang and Kathryn Foucar

Chapter 37 Plasma Cell Neoplasms and Immunoglobulin Deposition Diseases
Scott Ely, Ruben Niesvizky, and Tomer Mark

Chapter 38 Leukemias of Mature T-Cells and Natural Killer Cells
Dragan Jevremovic and William G. Morice

Chapter 39 Adult T-Cell Leukemia/Lymphoma
Koichi Ohshima and Shigeo Nakamura

Chapter 40 Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Michael J. Borowitz and Joseph A. DiGiuseppe

Chapter 41 Acute Myeloid Leukemia
Aharon G. Freud and Daniel A. Arber

Chapter 42 Plasmacytoid Dendritic Cell Neoplasms
Fabio Facchetti

Chapter 43 Myelodysplastic Syndromes
Richard D. Brunning and Ulrich Germing

Chapter 44 Myeloproliferative Neoplasms
John Anastasi and James W. Vardiman

Chapter 45 Myelodysplastic/Myeloproliferative Neoplasms and Related Diseases
Magdalena Czader and Attilio Orazi

Chapter 46 Myeloid Sarcoma
Stefano A. Pileri, Brunangelo Falini, Stefano Ascani, and Attilio Orazi

Chapter 47 Bone Marrow Morphologic Changes after Chemotherapy and Stem Cell Transplantation
Kaaren K. Reichard and Kathryn Foucar

Chapter 48 Histiocytic and Dendritic Cell Proliferations
Karen L. Chang and Lawrence M. Weiss

Chapter 49 Mastocytosis
Hans-Peter Horny, Karl Sotlar, and Peter Valent

Chapter 50 Histopathologic Manifestations of Lymphoproliferative and Myeloproliferative Disorders Involving the Spleen
Attilio Orazi and Sonam Prakash