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Ovarian Endocrinology
Pages 3-35
An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM.
Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.
Ovarian Endocrinology
Pages 3-35
Follicular Development and Oocyte Growth
Pages 37-57
A New Understanding on the Regulation of Oocyte Meiotic Prophase Arrest and Resumption
Pages 59-74
Mitochondria of the Oocyte
Pages 75-91
Natural Cycle IVF: Summary of the Current Literature
Pages 95-104
Follicular Fluid Hormone Profiles in Natural Cycle IVF Patients During Follicular Phase
Pages 105-128
Standard Ovarian Stimulation Protocols and Their Outcomes
Pages 129-146
Which Women Are Suitable for Natural and Modified Natural Cycle IVF?
Pages 147-155
Natural Cycle IVF with Spontaneous LH Surge
Pages 157-173
Risk Factors and Preventive Measures of Ovarian Hyperstimulation Syndrome
Pages 175-184
Prevention and Management of OHSS
Pages 185-191
Minimal or Mild Ovarian Stimulation for IVF: Overview
Pages 195-209
Cumulative Pregnancy Rates After Six Cycles of Modified Natural Cycle IVF
Pages 211-226
Minimal Stimulation for IVF with Clomiphene Citrate
Pages 227-235
Mild Stimulation Protocols: Combination of Clomiphene Citrate and Recombinant FSH or HMG
Pages 237-247
Mild Stimulation Protocol for Poor Ovarian Responders Undergoing IVF
Pages 249-255
The Application of Mild Stimulated Cycle IVF in Primary Ovarian Insufficiency
Pages 257-260
Mild Stimulation Protocols for Oncofertility Patients
Pages 261-265
Minimally Invasive IVF as an Alternative Treatment of Option for Infertility Couples: (INVO) Procedure
Pages 267-279
Accessible Infertility Care: From Dream to Reality
Pages 281-295
Genetic Aspect of Recurrent Implantation Failure
Pages 297-305
IVM as Clinical Treatment: Overview
Pages 309-316
Avoidance of Severe Ovarian Hyperstimulation with IVM Treatment
Pages 317-327
Immature Oocyte Retrieval for IVM Treatment
Pages 329-336
Laboratory Aspect of IVM Treatment
Pages 337-350
Obstetric Outcome of In Vitro Maturation Treatment and Risk of Congenital Malformations
Pages 351-358
Development of IVM Treatment: Combination of Natural Cycle IVF with IVM
Pages 359-366
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