Preface.  Prologue.  Botulinum toxin and its development in clinical medicine.  Botulinum neurotoxins: Pharmacology, immunology, and current developments.  Pharmacology and immunology of non-complexed botulinum neurotoxin.  Topical botulinum toxin.   The different botulinum toxins and their clinical uses in the West. The different botulinum toxins from around the world available for clinical use.   Botulinum toxin used in conjunction with other injectables and devices for cosmetic purposes.  Beyond the obvious: Beauty optimization with botulinum toxin.  Botulinum neurotoxin in the management of focal hyperhidrosis.  Botulinum neuromodulator type A (BoNT-A) treatment for depression, Raynaud’s and other novel dermatologic therapeutic applications.  Medicolegal considerations of cosmetic treatment with botulinum toxin injections.  Comparison of different consensus reports of botulinum neurotoxin dosing in different Western countries.  Functional facial anatomy, proportions of beauty, and neuromodulation.  Cosmetic uses of botulinum toxin A in the upper face.  Cosmetic uses of botulinum toxin A in the mid face.  Cosmetic uses of botulinum toxin A in the lower face, neck, and upper chest.  The use of botulinum toxin for the breast.  Aesthetic use of botulinum toxin in Asians.  Muscles of facial expression.  The preparation, handling, storage, and mode of injection of OnabotulinumtoxinA.  Patient treatment record.  Informed consent for the treatment of facial and body wrinkles with BoNTA.  Side effects and contraindications to BoNTA injections.