Informazioni
Non ci sono recensioni
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Acute Myeloid Leukemia
Röllig, Ossenkoppele
Editore
Springer
Anno
2021
Pagine
358
ISBN
9783030726782
115,00 €
DA SCONTARE
This book, written by a team of leading experts, provides a comprehensive overview of acute myeloid leukemia (AML), the most frequent acute leukemia in adults. The opening chapters present current knowledge of epidemiology, etiologic factors, and the pathogenesis and molecular development of AML. Detailed guidance is offered on laboratory and clinical diagnostic workup and disease classification, and the patient- and disease-related factors that determine prognosis and treatment allocation are identified. On the basis of these general considerations, initial treatments in patients considered fit for intensive treatment and in older and co-morbid patients are reviewed, and the available relapse treatment strategies, explained. For all clinical scenarios, the most recent data on the optimal use of newly approved agents in different AML subgroups are presented. Separate chapters address the treatment of acute promyelocytic leukemia, current practice of allogeneic stem cell transplantation, and special clinical situations. Finally, promising approaches in drug development, current standards and challenges in assessment of measurable residual disease, immune approaches, and ideas for innovative trial designs are considered.
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Epidemiology and Etiology of AML
Pages 1-22
Juliusson, Gunnar (et al.)
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Diagnosis and Classification of AML: WHO 2016
Pages 23-54
Voso, Maria Teresa (et al.)
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Germline Predisposition in AML
Pages 55-70
Ernst, M. P. T. (et al.)
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Secondary AML
Pages 71-101
Montesinos, Pau (et al.)
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Genomic Landscape and Clonal Evolution of AML
Pages 103-118
Noerenberg, Daniel (et al.)
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Clinical Manifestation and Diagnostic Workup
Pages 119-126
Wierzbowska, Agnieszka (et al.)
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Prognostic Factors in AML
Pages 127-175
Itzykson, Raphael (et al.)
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Management of Acute Promyelocytic Leukemia
Pages 177-197
Kayser, Sabine (et al.)
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Treatment of Newly Diagnosed AML in Fit Patients
Pages 199-213
Röllig, Christoph (et al.)
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Treatment of Newly Diagnosed AML in Unfit Patients
Pages 215-231
Vey, Norbert
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Treatment of Relapsed and Refractory AML: Intensive Approach in Fit Patients
Pages 233-240
Jaramillo, Sonia (et al.)
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Treatment of Relapsed and Refractory AML: Non-intensive Approach in Unfit Patients
Pages 241-254
Récher, Christian
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Allogeneic Hematopoietic Cell Transplantation
Pages 255-265
Bornhäuser, Martin
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Special Clinical Scenarios: Hyperleukocytosis
Pages 267-273
Bug, Gesine (et al.)
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Special Clinical Scenarios: Extramedullary Disease
Pages 275-283
Stölzel, Friedrich
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Special Clinical Scenarios: Infectious Complications and Prophylaxis
Pages 285-292
Sprute, Rosanne (et al.)
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Future Developments: Novel Agents
Pages 293-315
Chua, Chong Chyn (et al.)
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Future Developments: Measurable Residual Disease
Pages 317-337
Venditti, Adriano (et al.)
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Future Developments: Immunotherapy in AML
Pages 339-347
Subklewe, Marion
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Future Developments: Innovative Trial Design
Pages 349-358
Estey, Elihu
