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Epidemiology of Endometrial Cancers and Uterine Sarcomas
Pages 3-11
Uterine cancers are the commonest malignancies of the female genital tract in the developed world, and are increasing in numbers world over because of obesity and other life-style changes. Many of these malignancies are hereditary and thus, a better understanding of the genetic and molecular biology is needed. This would lead to appropriate treatment plan for improving the quality of life and long-term survival. This book addresses, in depth, all aspects of uterine malignancies covering both carcinomas and sarcomas. The book is divided into seven sections; the first two sections deal with epidemiology, molecular aspects, familial cancers and pathology and the later sections focus on diagnosis, imaging techniques and comprehensive management of both early stage and advanced cancers. Surgical techniques, adjuvant chemotherapy and radiotherapy have been covered in detail. Apart from the open surgical methods, role of laparoscopy and emerging role of robotic surgery in the contemporary management of endometrial cancers have been discussed. Written by authors with expertise in the field of gynecologic oncology from premier institutes, this book provides up-to-date information on best practice management of uterine malignancies.
Epidemiology of Endometrial Cancers and Uterine Sarcomas
Pages 3-11
Molecular Pathology and Cytogenetics of Endometrial Carcinoma, Carcinosarcoma, and Uterine Sarcomas
Pages 13-23
Hereditary Cancers of the Endometrium: HNPCC Syndrome and Beyond
Pages 25-32
Screening and Prevention of Carcinoma Endometrium
Pages 33-44
Clinical Evaluation of Abnormal Uterine Bleeding
Pages 45-51
Risk Factors, Diagnosis, and Staging of Endometrial Cancer
Pages 53-63
Imaging in Uterine Malignancy: Role of Ultrasonography, CT, and PET-CT
Pages 65-79
Magnetic Resonance Imaging in Endometrial Cancer
Pages 81-89
Steroid Receptors in Normal Endometrium and in Endometrial Cancer
Pages 93-104
Pathology of Endometrial Hyperplasia and Carcinoma
Pages 105-121
Pathology of Uterine Sarcomas
Pages 123-143
Prognostic and Predictive Factors in the Management of Carcinoma Endometrium
Pages 145-154
Surgical Anatomy of the Uterus
Pages 157-168
Endometrial Cancer Staging
Pages 169-178
Sentinel Node Evaluation in Endometrial Cancer
Pages 179-191
Surgery for Carcinoma Endometrium
Pages 193-200
Ovarian Preservation in Endometrial Carcinoma
Pages 201-205
The Role of Lymphadenectomy in Endometrial Cancer: The Mayo Clinic Experience
Pages 207-221
Extraperitoneal Laparoscopic Para-aortic Lymphadenectomy in Endometrial Cancer: Rationale and Surgical Technique
Pages 223-229
Role of Laparoscopic and Robotic Surgery in Endometrial Cancer: The Inevitable Evolution
Pages 231-247
Basics of Robotic Instrumentation and Robotic-Assisted Surgery for Endometrial Cancer
Pages 249-260
Adjuvant Radiation in Early-Stage Endometrial Cancer: Evidence, Principles, and Techniques
Pages 261-273
Therapeutic Options for Early-Stage Uterine Papillary Serous Carcinomas, Carcinosarcomas, and Clear-Cell and Mixed-Cell Histologies
Pages 275-282
Chemotherapy for High-Risk Early-Stage Endometrial Cancer: Current Evidence
Pages 283-292
Diagnosis and Management of Stage II Endometrial Cancer
Pages 293-305
Posttreatment Surveillance in Endometrial Cancer
Pages 307-309
Surgery for Advanced Endometrial Cancer
Pages 313-320
Systemic Treatment of Advanced Endometrial Carcinoma
Pages 321-327
Therapeutic Strategies in Recurrent and Metastatic Endometrial Cancer
Pages 329-335
Uterine Sarcomas: Risk Factors, Clinical Presentation, Diagnosis, and Staging
Pages 339-350
Surgical Management of Uterine Sarcoma
Pages 351-363
Role of Radiation Therapy in Uterine Sarcoma
Pages 365-368
Role of Systemic Therapy in the Management of Uterine Sarcomas
Pages 369-379
Surveillance of Uterine Sarcomas
Pages 381-383
Metabolic Syndrome and Endometrial Cancer
Pages 387-395
Management of Incompletely Staged Endometrial Cancer
Pages 397-403
Synchronous Cancers of the Ovary and Endometrium
Pages 405-409
Smooth Muscle Tumors of Uncertain Malignant Potential of Uterine Origin
Pages 411-416
Endometrial Cancers in Young Women: Conservative Management and Fertility Preserving Options
Pages 417-423
Hormone Therapy in Normal Postmenopausal Women and After Treatment for Endometrial Cancer
Pages 425-435
Effects of Tamoxifen and Other SERMs in the Endometrium and Follow-Up of Patients
Pages 437-441
Palliative Care and End of Life Options for Patients with Endometrial Cancer
Pages 445-459
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