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Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Understanding Evidence-Based Rheumatology
A Guide to Interpreting Criteria, Drugs, Trials, Registries, and Ethics
Yazici, Yazici, Lesaffre
Editore
Springer
Anno
2014
Pagine
276
ISBN
9783319083735
120,00 €
- Provides useful insight to anyone needing to assess or execute any kind of clinical study
- Based on trials’ successes and shortcomings and shows how they affected the currently used guideline in rheumatology
- Offers a multifaceted approach, from interpreting data to trial design, from analysis to presentation and publication of data
It is imperative that health professionals caring for patients with rheumatic diseases understand how to correctly interpret evidence in their field, taking into account the merits and shortcomings of available data. Understanding Evidence-Based Rheumatology offers a practical assessment of criteria, drugs, trials, and registries and provides useful tools for successfully interpreting this data. The book introduces readers to basic analysis of trial design, statistics, and application of data through no-nonsense, easy-to-follow insights. Using numerous examples, chapters outline the difficulties physicians encounter when measuring disease activity in rheumatology, and offer strategies for systematically approaching these situations. Ethical issues in study design and reporting are examined, and the book closes with a summary of future directions for scientific and clinical studies in rheumatology.
Understanding Evidence-Based Rheumatology is an invaluable resource for trainees, experienced clinicians, and scientists, preparing them with the necessary tools to correctly gather evidence and shed light on the difficult practice of rheumatology.
Table of Contents
Evidence-Based Medicine in Rheumatology:
How Does It Differ from Other Diseases?..................................................... 1
Theodore Pincus and Hasan Yazici
A Review of Statistical Approaches for the Analysis
of Data in Rheumatology................................................................................. 13
Emmanuel Lesaffre and Jolanda Luime
Disease Classification/Diagnosis Criteria....................................................... 65
Hasan Yazici and Yusuf Yazici
Biomarkers, Genetic Association, and Genomic Studies............................. 79
Mehmet Tevfik Dorak and Yusuf Yazici
Outcome Measures in Rheumatoid Arthritis................................................ 127
Yusuf Yazici and Hilal Maradit Kremers
Issues in Setting Up a Study and Data Collection......................................... 141
Hilal Maradit Kremers and Banu Çakir
The Randomized Controlled Trial: Methodological Perspectives............... 159
Emmanuel Lesaffre
Limitations of Traditional Randomized Controlled
Clinical Trials in Rheumatology..................................................................... 179
Theodore Pincus
Methodological Issues Relevant to Observational Studies,
Registries, and Administrative Health Databases in Rheumatology.......... 209
Marie Hudson and Samy Suissa
Systematic Reviews and Meta-analyses in Rheumatology........................... 229
Theo Stijnen and Gulen Hatemi
