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When and How Did It All Begin? A Brief History of Intravenous Anesthesia
Pages 3-8
This is a comprehensive and authoritative presentation of total intravenous anesthesia (TIVA) and target controlled infusion (TCI). The editors’ international reputation has enabled them to recruit leading experts from around the world to write single-author chapters in their area of expertise. Total Intravenous Anesthesia and Target Controlled Infusions is the first multi-disciplinary, globally authored volume on the topic.
Providing a single source of information on all aspects of TIVA and TCI, from pharmacologic modeling and the pharmacology of intravenous anesthetic drugs to practical considerations in the clinical setting and the requirements of special populations, Total Intravenous Anesthesia and Target Controlled Infusions examines the debate about the risks and advantages of TIVA, analyze outcome studies, and provides guidance on creating a curriculum to teach TIVA and TCI.
When and How Did It All Begin? A Brief History of Intravenous Anesthesia
Pages 3-8
The Development and Regulation of Commercial Devices for Target-Controlled Drug Infusion
Pages 9-29
The Memory Labyrinth: Systems, Processes, and Boundaries
Pages 31-62
Consciousness and Anesthesia
Pages 63-78
Mechanisms of Intravenous Anesthetic Action
Pages 79-95
Basic Pharmacology: Kinetics and Dynamics for Dummies
Pages 99-116
Pharmacokinetic–Pharmacodynamic Modelling of Anesthetic Drugs
Pages 117-145
Principles of Target-Controlled Infusions
Pages 147-157
Performance of Target-Controlled Infusion Systems
Pages 159-170
How to Select a PK/PD Model
Pages 171-187
Propofol PK-PD
Pages 191-208
Etomidate and Etomidate Analogues: Molecular Pharmacology and Behavioral Actions
Pages 209-219
Dexmedetomidine: The Science and Clinical Aspects in Adults and Children
Pages 221-244
Clinical Effects and Applications of Ketamine
Pages 245-265
Neuromuscular Blocking Drugs: Physiology, Pharmacology and Clinical Aspects
Pages 267-297
New and Upcoming Drugs: Intravenous Anesthetic Agents
Pages 299-312
Drug Interactions in Anesthesia
Pages 313-325
Pump Pitfalls and Practicalities
Pages 329-340
EEG Monitoring of Depth of Anesthesia
Pages 341-356
Monitoring the Analgesic Component of Anesthesia
Pages 357-368
Intravenous Drugs for Sedation: Target-Controlled, Patient-Controlled and Patient-Maintained Delivery
Pages 369-390
Pediatric TIVA/TCI: Case Presentations and Discussion
Pages 391-401
TCI/TIVA Adult Case Studies
Pages 403-425
Intravenous Anesthesia in Obese Patients
Pages 429-440
Pharmacokinetics and Pharmacodynamics in the Pediatric Patient
Pages 441-516
Clinical Pharmacology of Intravenous Sedation in Children
Pages 517-535
Sedation of the Critically Ill Child
Pages 537-560
TCI and TIVA for Neurosurgery: Considerations and Techniques
Pages 561-569
TCI in Special Patients Groups: The Elderly and Obese
Pages 571-578
TIVA for Cardiac Surgery
Pages 579-588
TIVA/TCI in Veterinary Practice
Pages 589-618
Advantages, Disadvantages, and Risks of TIVA/TCI
Pages 621-631
Economics of TIVA
Pages 633-638
Teaching TCI with Human Patient Simulators
Pages 639-648
Closed-Loop or Automated Titration of Intravenous Anesthesia: Background, Science, and Clinical Impact
Pages 649-666
Health Care Technology, the Human–Machine Interface, and Patient Safety During Intravenous Anesthesia
Pages 667-683
Can IV Sedatives Affect Outcome?
Pages 685-696
The Benefit and Future of Pharmacogenetics
Pages 697-711
Lessons From Drug Interaction Displays
Pages 713-723
The Role of Intravenous Agents in Delirium
Pages 725-748
Perioperative Cardioprotective Strategies in Noncardiac Surgery
Pages 749-761
Opioid-Induced Hyperalgesia After Surgery: Clinical Relevance
Pages 763-773
Memory, Awareness and Intravenous Anesthetics
Pages 775-782
Awareness and Dreaming During TIVA
Pages 783-796
Apoptosis and Neurocognitive Effects of IV Anesthetics
Pages 797-803
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