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Anatomy and Physiology of the Thyroid Gland: Clinical Correlates to Thyroid Cancer
Pages 3-8
Thoroughly revised and extensively expanded, this encyclopedic, highly acclaimed title addresses all aspects of the etiology, pathogenesis, diagnosis, initial treatment and long-term management of all varieties of thyroid cancer. Expertly edited by Drs. Leonard Wartofsky and Douglas Van Nostrand, this gold standard reference is divided into 11 Parts: General Considerations on Thyroid Cancer; General Considerations on Nuclear Medicine; the Thyroid Nodule; Well-Differentiated Thyroid Cancer; Variants of Thyroid Cancer, Undifferentiated Tumors: Medullary Thyroid Carcinoma; Undifferentiated Tumors: Thyroid Lymphoma; Undifferentiated Tumors: Anaplastic Thyroid Cancer; New Frontiers and Future Directions; and Additional Resources. With exceptional breadth and depth, the book includes chapters dedicated to isotopes, isotope uptake and scanning procedures such as SPECT/CT, radioiodine ablation (with or without recombinant human TSH), stunning, dosimetry (with or without recombinant human TSH), Octreotide and FDG-PET scanning and other alternative imaging modalities. There is a valuable reference atlas of scan images and illustrations, and a scholarly summary of the side effects of radioiodine and how to avoid or minimize adverse effects of treatment. In addition to an updated section on ultrasonography of the thyroid gland, new sections have been added, including ones on ultrasonography of cervical lymph nodes and imaging for thyroid cancer employing computerized tomography (CT), positron emission tomography (PET) and magnetic resonance imaging (MRI). An indispensable reference source with chapters written by the field’s leading authoritative experts, Thyroid Cancer: A Comprehensive Guide to Clinical Management, Third Edition, will be of great interest to not only pathologists, endocrine surgeons, endocrinologists, nuclear medicine physicians, and oncologists but all clinicians with an interest in thyroid cancer.
Anatomy and Physiology of the Thyroid Gland: Clinical Correlates to Thyroid Cancer
Pages 3-8
Epidemiology of Thyroid Cancer
Pages 9-15
Molecular Pathogenesis of Thyroid Cancer and Oncogenes in Thyroid Cancer
Pages 17-30
Molecular Aspects of Thyroid Cancer in Children
Pages 31-41
The Role of Genetics in the Development of Familial Nonmedullary Thyroid Cancer
Pages 43-70
Apoptosis in Thyroid Cancer
Pages 71-77
Radiation-Induced Thyroid Cancer
Pages 79-100
Classification of Thyroid Malignancies
Pages 101-104
Staging of Thyroid Cancer
Pages 105-117
Recombinant Human Thyrotropin
Pages 119-129
Radioiodine Whole-Body Imaging
Pages 133-152
Primer and Atlas for the Interpretation of Radioiodine Whole Body Scintigraphy
Pages 153-184
False-Positive Radioiodine Scans in Thyroid Cancer
Pages 185-204
The Utility of SPECT-CT in Differentiated Thyroid Cancer
Pages 205-214
Radioiodine Scintigraphy with SPECT/CT: An Important Diagnostic Tool for Staging and Risk Stratification
Pages 215-223
Stunning by
Pages 225-235
Stunning Is Not a Problem
Pages 237-241
Stunning: Does It Exist? A Commentary
Pages 243-244
To Perform or Not to Perform Radioiodine Scans Prior to
Pages 245-254
The Thyroid Nodule: Evaluation, Risk of Malignancy, and Management
Pages 257-275
Fine-Needle Aspiration
Pages 277-280
Diagnostic and Prognostic Molecular Markers in Thyroid Cancer
Pages 281-292
Ultrasonic Imaging of the Thyroid Gland
Pages 293-314
Radionuclide Imaging of Thyroid Nodules
Pages 315-322
Pages 323-330
Thyroid Nodules and Cancer Risk: Surgical Management
Pages 331-333
Thyroid Nodules in Children and Cancer Risk
Pages 335-346
Management of the Thyroid Nodule: A Comparison of Published International Guidelines
Pages 347-355
Papillary Carcinoma: Clinical Aspects
Pages 359-370
Papillary Microcarcinoma
Pages 371-376
Surgical Approach to Papillary Thyroid Cancer
Pages 377-379
Papillary Carcinoma: Cytology and Pathology
Pages 381-391
Remnant Ablation, Adjuvant Treatment and Treatment of Locoregional Metastases with
Pages 395-409
Thyroid Remnant Radioiodine Ablation with Recombinant Human Thyrotropin
Pages 411-416
Follow-Up Strategy in Papillary Thyroid Cancer
Pages 419-425
Thyroid Hormone Therapy and Thyrotropin Suppression
Pages 427-432
Thyroglobulin for Differentiated Thyroid Cancer: Measurement and Interferences
Pages 433-442
Thyroglobulin Antibodies and Their Measurement
Pages 443-447
Diagnosis of Recurrent Thyroid Cancer in Patients with Anti-thyroglobulin Antibodies
Pages 449-454
Ultrasound of the Neck Lymph Nodes
Pages 455-470
Surveillance Radioiodine Whole Body Scans
Pages 471-473
Radionuclide Imaging and Treatment of Children with Thyroid Cancer
Pages 475-485
Positron Emission Tomography-Computed Tomography (PET-CT and PET) in Well-Differentiated Thyroid Cancer
Pages 487-504
Alternative Thyroid Imaging
Pages 505-513
MR and CT Imaging of Thyroid Cancer
Pages 515-524
Thyroglobulin in Lymph Node Aspirate
Pages 525-528
Management of the Patients with Negative Radioiodine Scan and Elevated Serum Thyroglobulin
Pages 529-538
Prognosis in Papillary Thyroid Cancer
Pages 539-542
Surgical Management of Lymph Node Metastases
Pages 543-544
Utility of Second Surgery for Lymph Node Metastases
Pages 545-550
Papillary Cancer: Special Aspects in Children
Pages 551-563
Special Presentations of Thyroid Cancer in Thyrotoxicosis, Renal Failure, and Struma Ovarii
Pages 565-568
Thyroglossal Duct Carcinoma
Pages 569-572
Thyroid Cancer in Pregnancy
Pages 573-582
Radiation and Radioactivity
Pages 585-593
Pages 595-627
Treatment of Metastatic Thyroid Cancer with Radioiodine Following Preparation by Recombinant Human Thyrotropin
Pages 629-634
Dosimetrically Determined Prescribed Activity of
Pages 635-650
Simplified Methods of Dosimetry
Pages 651-656
Radioiodine Dosimetry with Recombinant Human Thyrotropin
Pages 657-664
The Use of Lithium as an Adjuvant to Radioiodine in the Treatment of Thyroid Cancer
Pages 665-669
Side Effects of
Pages 671-708
External Radiation Therapy for Papillary Carcinoma
Pages 709-715
Chemotherapy of Thyroid Cancer: General Principles
Pages 717-721
Bone Metastases from Differentiated Thyroid Carcinoma
Pages 723-733
A Summary of Rare Sites of Metastasis Secondary to Differentiated Thyroid Cancer
Pages 735-744
Adjunctive Local Approaches to Thyroid Nodules and Metastatic Thyroid Cancer
Pages 745-750
Radioiodine-Refractory Thyroid Cancer: Restoring Response to Radioiodine Therapy
Pages 751-758
Alternative and Complementary Treatment of Thyroid Disorders
Pages 759-765
Follicular Thyroid Carcinoma
Pages 769-778
Surgical Management of Follicular Cancer
Pages 779-780
Pathology of Follicular Cancer
Pages 781-786
Hürthle Cell Carcinoma
Pages 787-791
Follow-Up Strategy in Follicular Thyroid Cancer
Pages 793-796
Radionuclide Imaging and
Pages 797-798
PET/CT in Follicular Cancer Including Hürthle Cell Cancer
Pages 799-800
Follicular Thyroid Cancer: Special Aspects in Children and Adolescents
Pages 801-805
External Radiation Therapy for Follicular Carcinoma
Pages 807-810
Determinants of Prognosis of Follicular Thyroid Carcinoma
Pages 811-813
Aggressive Variants of Papillary Thyroid Carcinoma and Poorly Differentiated Carcinoma
Pages 817-823
Miscellaneous and Unusual Tumors of the Thyroid Gland
Pages 825-843
Pathology of Miscellaneous and Unusual Cancers of the Thyroid
Pages 845-849
Clinical Aspects of Medullary Thyroid Carcinoma
Pages 853-863
Cytology and Pathology of Medullary Thyroid Cancer
Pages 865-869
Medullary Carcinoma of the Thyroid: Surgical Management
Pages 871-872
Radionuclide Imaging of Medullary Carcinoma
Pages 873-880
PET/CT in Medullary Thyroid Cancer
Pages 881-886
External Radiation Therapy for Medullary Cancer
Pages 887-890
Medullary Carcinoma of the Thyroid: Chemotherapy
Pages 891-897
A Comparison of the ATA, NCCN, ETA, and BTA Guidelines for the Management of Medullary Thyroid Cancer
Pages 899-910
Thyroid Lymphoma
Pages 913-920
Pathology of Lymphoma of the Thyroid
Pages 921-922
PET/CT in Lymphoma and Lymphoma of the Thyroid
Pages 923-926
Anaplastic Thyroid Carcinoma: Clinical Aspects
Pages 929-932
Surgical Management of Anaplastic Thyroid Carcinoma
Pages 933-934
Pathology of Anaplastic Carcinoma
Pages 935-937
PET/CT in Anaplastic Cancer of the Thyroid
Pages 939-941
External Radiation Therapy for Anaplastic Thyroid Cancer
Pages 943-945
Chemotherapy for Anaplastic Thyroid Cancer
Pages 947-952
Anaplastic Thyroid Carcinoma: Prognosis
Pages 953-956
Advances in Radiation Therapy
Pages 959-962
New Approaches in Nuclear Medicine for Thyroid Cancer
Pages 963-971
Pages 973-989
Future Directions for Advanced Thyroid Cancer Therapy
Pages 991-999
Potential Approaches to Chemotherapy of Thyroid Cancer in the Future
Pages 1001-1006
Prophylaxis Against Radiation Exposure from Radioiodine
Pages 1009-1013
Low-Iodine Diets
Pages 1015-1019
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