PART I INTRODUCTION
1 Sepsis: Past, Present, and Futured Lessons Learned from COVID-19
2 Sepsis Definitions: A Historical Perspective
3 The Epidemiology of Sepsis
PART II BASIC CONCEPTS
4 Pathophysiology of Sepsis
5 Sepsis and Microcirculation
6 Genetics and Sepsis
PART III DIAGNOSIS AND MONITORING
7 Screening and early detection of sepsis
8 Diagnosis and Monitoring of Sepsis
9 Sepsis: Molecular Diagnostics and Biomarkers
10 Hemodynamic Monitoring: Current Practice and New Perspectives
11 Point of Care Ultrasound in the Management of Sepsis
12 New Approaches and Understanding of Sepsis
13 Sepsis Quality Indicators in the Emergency Department
PART IV TREATMENT
14 Sepsis Treatment: Fluids
15 Vasopressor Therapy in Septic Shock
16 Mechanical Ventilation in Sepsis
17 Extracorporeal Membrane Oxygenation for the Support of Patients with Refractory Septic Shock
18 Antimicrobials in the Management of Sepsis
19 Kidney Support in Sepsis
20 Hematological Support in Sepsis
21 Specific Treatment of Focus Control in Sepsis
22 Sepsis Adjunctive Therapies
23 Glycemic Control and Stress Ulcer Prophylaxis
24 Nutrition in Sepsis
PART V SPECIAL SETTINGS
25 Fever in Intensive Care Units
26 SepsisdIn the Era of Antimicrobial Resistance
27 Factors Underlying Racial and Gender Disparities in Sepsis Management
28 Sepsis in Special Populations
29 Comprehensive Management of Sepsis in Pediatrics
30 Maternal Sepsis
PART VI SPECIAL CONSIDERATIONS
31 Role of Preventive Measures in Sepsis
32 Value of the Protocolization and Sepsis Performance Improvement Program in Early Identification
33 Long-Term Sequelae of Sepsis
PART VII FUTURE OUTLOOK
34 New Diagnostic and Therapeutic Perspectives
35 Artificial Intelligence in Sepsis
INDEX