Titolo: The Plasticity of Skeletal Muscle

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Medicina Fisica - Riabilitativa - Fisiatria - Fisioterapia

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The Plasticity of Skeletal Muscle

From Molecular Mechanism to Clinical Applications

Editore

Springer

Anno

2017

Pagine

292

ISBN

9789811032912

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This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis.

The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered.

It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.

Pluripotent Stem Cells and Skeletal Muscle Differentiation: Challenges and Immediate Applications

Garreta, Elena (et al.)

Pages 1-35
Role of the Ubiquitin-Proteasome Pathway in Skeletal Muscle

Kitajima, Yasuo (et al.)

Pages 37-54
Stem Cell Therapy in Muscle Degeneration

Duelen, Robin (et al.)

Pages 55-91
The Autophagy-Dependent Signaling in Skeletal Muscle

Sakuma, Kunihiro (et al.)

Pages 93-111
Cytokines in Skeletal Muscle Growth and Decay

Orzechowski, Arkadiusz

Pages 113-139

The Role of Ribosome Biogenesis in Skeletal Muscle Hypertrophy

Figueiredo, Vandre Casagrande (et al.)

Pages 141-153
Comprehensive Approach to Sarcopenia and Cachexia Treatment

Wakabayashi, Hidetaka (et al.)

Pages 155-178
The Role and Regulation of PGC-1α and PGC-1β in Skeletal Muscle Adaptation

Lamon, Séverine (et al.)

Pages 179-194
Characteristics of Skeletal Muscle as a Secretory Organ

Aoi, Wataru

Pages 195-210
Biological Role of TRPC1 in Myogenesis, Regeneration, and Disease

Yeung, Ella W. (et al.)

Pages 211-230
ROS and nNOS in the Regulation of Disuse-Induced Skeletal Muscle Atrophy

Hord, Jeffrey M. (et al.)

Pages 231-250
Participation of AMPK in the Control of Skeletal Muscle Mass

Egawa, Tatsuro

Pages 251-275
Therapeutic Potential of Skeletal Muscle Plasticity and Slow Muscle Programming for Muscular Dystrophy and Related Muscle Conditions

Lynch, Gordon S.

Pages 277-292