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The first edition of The Paris System for Reporting Urinary Cytology introduced a completely new paradigm for detecting bladder cancer by urine cytology. This system concentrated on defining morphological characteristics of the most clinically significant form of bladder cancer, High Grade Urothelial Carcinoma. This new approach has been widely accepted throughout the world, and has become part of the daily practice of cytology. Considering that the first edition of The Paris System (TPS) introduced a new model of urinary cytodiagnosis, verification and expansion of initial material and data were anticipated. Based on evolving knowledge and readership requests, the group of highly experienced authors have created a new edition of TPS. This second edition includes areas and issues not originally covered. A new chapter on urine cytology of the upper tract, a rarely addressed topic, has been introduced. Furthermore, the issue of cellular degeneration is discussed in the criteria of all diagnostic categories. Examples of standardized reports are included in each chapter. Most importantly, a separate chapter presents data defining the risk of malignancy (ROM) for each diagnostic category to inform clinical management. New high quality images augment those of the first edition to better illustrate diagnostic clues and potential pitfalls. In addition to chapters on diagnostic criteria, current concepts of pathogenesis of bladder cancer, specimen adequacy and preparation, and ancillary tests are covered in separate chapters. A bonus to the volume is a comprehensive history of urine as the earliest diagnostic sample of human disease, richly illustrated with artworks from major museums.
Written by internationally recognized authorities, this comprehensive and evidence-based guide to urine cytology is supported by the newest data confirming the original concept and significance of diagnostic criteria defining High Grade Urothelial Carcinoma. TPS is an essential tool for anyone who is practicing urinary cytology, including cytotechnologists, pathologists-in-training and practicing pathologists. This book should find a place in every cytology laboratory throughout the world.
The Concept has been endorsed by the American Society of Cytopathology, and the International Academy of Cytology.
Pathogenesis of Urothelial Carcinoma
Kaitlin E. Sundling, Tatjana Antic, Stefan E. Pambuccian
Pages 1-5
Adequacy of Urine Specimens (Adequacy)
Z. Laura Tabatabai, Güliz A. Barkan, Monique Courtade-Saïdi, Daniel F. I. Kurtycz, Matthew T. Olson, Toyonori Tsuzuki et al.
Pages 7-19
Negative for High-Grade Urothelial Carcinoma (NHGUC)
Christopher J. VandenBussche, Ashish Chandra, Jonas J. Heymann, Zulfia McCroskey, Christopher L. Owens, Pawel T. Schubert et al.
Pages 21-62
Atypical Urothelial Cells (AUC)
Güliz A. Barkan, Margaret L. Compton, Tarik M. Elsheikh, Kim A. Ely, Daniel F. I. Kurtycz, Merce Jorda et al.
Pages 63-83
Suspicious for High-Grade Urothelial Carcinoma (SHGUC)
Fadi Brimo, Manon Auger, Ivan Chebib, Tarik M. Elsheikh, Mitsuru Kinjo, Eric Piaton et al.
Pages 85-96
High-Grade Urothelial Carcinoma (HGUC)
Momin T. Siddiqui, Derek B. Allison, Guido Fadda, Jee-Young Han, Patrick J. McIntire, Christopher L. Owens et al.
Pages 97-114
Cytopathology of the Upper Urinary Tract
Christopher J. VandenBussche, Jen-Fan Hang, Patrick J. McIntire, Yurina Miki, Stephen Peyton, Poonam Vohra et al.
Pages 115-141
Non-Urothelial Malignancies and Other Miscellaneous Lesions
Tarik M. Elsheikh, Rana S. Hoda, Stefan E. Pambuccian, Jae Y. Ro, Sun Hee Sung
Pages 143-192
Ancillary Studies in Urinary Cytology
Lukas Bubendorf, Nancy P. Caraway, Andrew H. Fischer, Ruth L. Katz, Fernando Schmitt, Margareta Strojan Fležar et al.
Pages 193-220
Donna K. Russell, Willam N. Crabtree, Gary W. Gill
Pages 221-247
Risk of High-Grade Malignancy (ROHM)
Mauro Saieg, Güliz A. Barkan, Fadi Brimo, Ashish Chandra, Tarik M. Elsheikh, Ricardo G. Pastorello et al.
Pages 249-255
Marcus L. Quek, Trinity J. Bivalacqua, Ashish M. Kamat, Mauro Saieg, Alexander I. Sankin, Yuji Tokuda et al.
Pages 257-266
The History of Urinary Cytology: The Long and Winding Road to Paris 2.0
Stefan E. Pambuccian
Pages 267-315
Pages 317-329
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