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The Duration and Safety of Osteoporosis Treatment
Anabolic and Antiresorptive Therapy
Silverman, Abrahamsen
Editore
Springer
Anno
2016
Pagine
338
ISBN
9783319236384
120,00 €
I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.
  • Focuses on the duration and safety of anabolic and antiresorptive drug therapies for osteoporosis
  • Examines common and serious side effects of extended drug treatment, especially bisphosphonates 
  • Discusses diagnosis and management of osteonecrosis of the jaw and atypical femur fractures

Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.

Table of contents (23 chapters)

 
  • Osteoporosis: Pathophysiology and Epidemiology

    Moon, Rebecca J. (et al.)

    Pages 1-16

  • Antiresorptives

    Russell, R. Graham G. (et al.)

    Pages 17-36

  • Anabolics

    Eriksen, Erik Fink

    Pages 37-59

  • Tools for Assessing Fracture Risk and for Treatment Monitoring

    Leslie, William D. (et al.)

    Pages 61-83

  • Treatment Failure

    Pliego, Elisa Torres (et al.)

    Pages 85-94

  • Epidemiology of Atypical Subtrochanteric and Femoral Shaft Fractures

    Nieves, Jeri W.

    Pages 95-106

  • Bisphosphonate-Related Atypical Femur Fractures and Their Radiographic Features

    Giaconi, Joseph C. (et al.)

    Pages 107-124

  • Factors Contributing to Atypical Femoral Fractures

    Boskey, Adele L. (et al.)

    Pages 125-136

  • Clinical Presentation of Atypical Femur Fractures

    Bogdan, Yelena (et al.)

    Pages 137-140

  • Effects of Antiresorptive Therapy on Bone Microarchitecture

    Tsai, Joy N. (et al.)

    Pages 141-152

  • Management of Atypical Femoral Fractures

    Lane, Joseph M. (et al.)

    Pages 153-162

  • Osteonecrosis of the Jaw: Clinicopathologic and Radiologic Features

    Sedghizadeh, Parish P. (et al.)

    Pages 163-184

  • Epidemiology of Osteonecrosis of the Jaws from Antiresorptive Treatment

    Schiødt, Morten

    Pages 185-192

  • Management of Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Treatment

    Schiødt, Morten

    Pages 193-202

  • Long-Term Efficacy and Safety of Treatments for Osteoporosis

    Papapoulos, Socrates E.

    Pages 203-232

  • Management of Drug Holidays

    Roux, Christian (et al.)

    Pages 233-237

  • Patients Who Do Not Take Their Osteoporosis Medications: Can We Help Them Become Compliant?

    Gold, Deborah T.

    Pages 239-253

  • Fractures and Healing on Antiresorptive Therapy

    Kupperman, Eli (et al.)

    Pages 255-264

  • Antiresorptive Therapy, Mortality and Cancer Incidence

    Vestergaard, Peter

    Pages 265-278

  • Other Safety Concerns

    McClung, Michael R.

    Pages 279-293

  • The Impact of Regulatory and Scientific Organizations’ Recommendations on Clinical Decision-Making

    Papaioannou, Alexandra (et al.)

    Pages 295-308

  • Integrated Clinical View on Long-Term Management of Patients with Osteoporosis

    Lewiecki, E. Michael

    Pages 309-320

  • Conclusions

    Silverman, Stuart L. (et al.)

    Pages 321-325

 

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