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Genetics of Fibroinflammatory Disorders
Pages 1-16
This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement. Among the conditions considered are IgG4-related disease, sclerosing cholangitis, Hashimoto’s and Riedel’s thyroiditis, retroperitoneal fibrosis/chronic periaortitis, mediastinal fibrosis, Erdheim-Chester disease, gadolinium-induced fibrosis, and sclerosing mesenteritis. This group of entities is still poorly defined and is characterized by the common denominator of chronic inflammatory infiltrate admixed with abundant fibrosis. IgG4-related disease is the prototypical example. Systemic Fibroinflammatory Disorders is the first book to draw together information on these conditions. As these diseases often require an interdisciplinary approach, the book is addressed to specialists of different disciplines, especially internists, rheumatologists, nephrologists, clinical immunologists, and hematologists.
Genetics of Fibroinflammatory Disorders
Pages 1-16
Basic Mechanisms Linking Inflammation and Fibrosis
Pages 17-31
The Pathology of Systemic Fibroinflammatory Disorders
Pages 33-51
IgG4-Related Disease: A Prototypical Fibroinflammatory Disease. Overview on Clinical and Therapeutic Aspects
Pages 53-70
Pathophysiology of IgG4-Related Disease
Pages 71-80
Autoimmune (IgG4-Related) Pancreatitis
Pages 81-90
Sclerosing Forms of Autoimmune Thyroiditis: Hashimoto’s, Riedel’s, and IgG4-Related Forms
Pages 91-100
Retroperitoneal Fibrosis and the Spectrum of Chronic Periaortitis
Pages 101-115
Diffuse (Thoraco-Abdominal) Periaortitis
Pages 117-126
Idiopathic Mediastinal Fibrosis
Pages 127-135
Sclerosing Mesenteritis
Pages 137-153
Erdheim-Chester Disease and Other Histiocytoses
Pages 155-172
Malignant Diseases Mimicking Retroperitoneal and Mediastinal Fibrosing Disorders
Pages 173-194
Drug-Induced Fibrosing Lesions
Pages 195-207
Gadolinium-Induced Fibrosis
Pages 209-237
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