Section I:  PHYSIOLOGY AND PHARMACOLOGY 1. Physiologic Changes of Pregnancy Brenda A. Bucklin and Andrea J. Fuller 2. Uteroplacental Circulation and Respiratory Gas Exchange Mark I. Zakowski and Sivam Ramanathan 3. Placental Transfer of Drugs and Perinatal Pharmacology David Campbell and Monica San Vicente Section II:  ASSESSMENT OF THE FETUS 4. Antenatal Fetal Assessment, Therapy, and Outcomes Christina Davidson 5. Intrapartum Fetal Monitoring: Old and New Concepts Michelle Simon, Rakesh B. Vadhera, George R. Saade Section III: ANALGESIA AND ANESTHESIA FOR LABOR AND VAGINAL DELIVERY 6.  Alternative (Non-pharmacologic) Methods of Labor Analgesia Katherine W. Arendt and William Camann   7. Systemic and Inhalational Agents for Labor Analgesia Samantha Wilson and Roshan Fernando 8. Local Anesthetics in Obstetrics: Evidence-based Applications, Controversies, Toxicity, and Current Therapies Barbara M. Scavone 9. Regional Analgesia/Anesthesia Techniques in Obstetrics Manuel C. Vallejo 10. Anesthesia for Vaginal Birth After Cesarean Delivery Chawla LaToya Mason and Nikolaos Marios Zacharias 11. Effects of Anesthesia on Uterine Activity, Progress in Labor and Outcomes Elena Reitman, Pamela Flood, Mrinalini Balki Section IV: ANESTHESIA FOR CESAREAN DELIVERY: MANAGEMENT OF POSTOPERATIVE AND POSTPARTUM ISSUES 12.  Anesthesia for Cesarean Delivery McCallum R. Hoyt 13. Postoperative Multimodal Acute Pain Management: Cesarean and Vaginal Delivery Rodolfo Gebhardt, Sarah L. Armstrong, Oscar A. de Leon-Casasola, Thomas Chai, Julie A. Sparlin, Jose M. Rivers,  Roshan Fernando 14. Chronic Pain Issues After Cesarean Delivery Ruth Landau 15. Anesthesia for Nondelivery Obstetric Procedures Christopher R. Cambic and Feyce M. Peralta Section V: NEONATAL WELL-BEING: OLD AND NEW CONCEPTS 16. Neonatal Resuscitation Emily J. Baird, Richard C. Month, Valerie A. Arkoosh 17. Management of Neonatal Neurologic Injury: Evidence-based Outcomes Mihaela Podovei and Bhavani Shankar Kodali Section VI: ANESTHETIC CONSIDERATIONS AND MANAGEMENT OF OBSTETRIC COMPLICATIONS 18.  Abnormal Fetal Positions, Breech Presentations, Shoulder Dystocia, and Multiple Gestation Thomas Gough and Paul Howell 19. Preterm Labor and Delivery Carlo Pancaro 20. Intrapartum Fever, Infection, and Sepsis Laura Goetzl 21. Obstetric Hemorrhage, Novel Pharmacologic Interventions, Blood Conservation Techniques, and Hemorrhage Protocols Ashutosh Wali and Jonathan H. Waters Section VII: RISKS, STRATEGIES AND MANAGEMENT OF ANESTHETIC COMPLICATIONS 22. Amniotic Fluid Embolism Quisqueya T. Palacios 23. Venous Thromboembolism in Pregnancy and Guidelines for Neuraxial Anesthesia Following Anticoagulant and Antithrombotic Drugs Quisqueya T. Palacios 24. Difficult and Failed Intubation: Strategies, Prevention and Management of Airway-related Catastrophes in Obstetrical Patients Maya S. Suresh, Ashutosh Wali, Edward T. Crosby 25. NPO Controversies—Pulmonary Aspiration: Risks and Management Geraldine O’Sullivan and Scott Segal 26. Neurologic Complications of Regional Anesthesia in Obstetrics David Wlody 27. Postdural Puncture Headache Alice Lam Oswald Section VIII: ANESTHETIC MANAGEMENT OF THE PARTURIENT WITH COEXISTING DISORDERS 28. Hypertensive Disorders of Pregnancy Jaya Ramanathan, Ravpreet Singh Gill, Baha Sibai 29. Anesthesia for Pregnant Patients with Endocrine Disorders Peter H. Pan and Ashley M. Tonidandel 30. Anesthetic Management of the Pregnant Cardiac Patient Shobana Chandrasekhar, Daniel A. Tolpin, Dennis T. Mangano 31. Asthma in Pregnancy Uma Munnur and Venkata Bandi 32. Neurologic and Neuromuscular Disorders Stephanie R. Goodman and Suzanne Wattenmaker Mankowitz 33. The Parturient with Intracranial and Spinal Pathology Ellen Lockhart and Curtis Baysinger 34. New Thoughts on Bleeding and Coagulation Disorders Moeen K. Panni 35. Morbid Obesity J. Sudharma Ranasinghe and Donald H. Penning 36. Human Immunodeficiency Virus: Maternal and Fetal Considerations and Management Roulhac D. Toledano and May C. M. Pian-Smith 37. Renal and Hepatic Disorders in Pregnancy Michael Paech 38. Anesthesia for the Pregnant Patient with Immunologic Disorders Stephen H. Halpern and Margaret Srebrnjak 39. Psychiatric Disorders Julio Delgado and Michael Fru00f6lich 40. Parturient with Pre-existing Congenital Anomalies David G. Mann Section IX: ETHICAL, MEDICAL, AND SOCIAL CHALLENGES AND ISSUES 41. Informed Consent and Other Ethical and Legal Issues in Obstetric Anesthesia William J. Sullivan and M. Joanne Douglas 42. Substance Abuse and the Drug-addicted Mother John T. Sullivan 43. Jehovah’s Witness: Ethical and Anesthetic-related Issues Connie Tran 44. Trauma During Pregnancy: Maternal Resuscitation, Rapid Response Team, and Protocols Sally Radelat Raty, Kenneth L. Mattox, Uma Munnur, Andrew Miller, Mihaela Podovei Section X: MATERNAL SAFETY, MORBIDITY, AND MORTALITY 45. Utilization of Crisis Resource Management and Simulation in Maternal and Neonatal Safety Stephen D. Pratt 46. Near Misses and Maternal Mortality Joy L. Hawkins 47. Global Perspective on Obstetric Anesthesia Holly Muir and Medge Owen Section XI: ANESTHETIC CONSIDERATIONS FOR REPRODUCTIVE, IN-UTERO AND NON-OBSTETRIC PROCEDURES 48. In vitro Fertilization and Reproductive Technologies Roanne Preston and Katherine Cheesman 49. In Utero Fetal Surgery and Ex Utero Intrapartum Therapy (EXIT) David G. Mann and Olutoyin A. Olutoye 50. Non-obstetric Surgery during Pregnancy Yaakov Beilin APPENDICES A Guidelines for Neuraxial Anesthesia in Obstetrics B Practice Guidelines for Obstetric Anesthesia: An Updated Report by the American Society of Anesthesiologists Task Force on Obstetric Anesthesia C Optimal Goals for Anesthesia Care in Obstetrics D Intrapartum Fetal Heart Rate Monitoring: Nomenclature, Interpretation, and General Management Principles