Informazioni
Non ci sono recensioni
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Sex, Gender, and Epigenetics
Legato J
Editore
Elsevier
Anno
2023
Pagine
313
ISBN
9780128239377
155,00 €
DA SCONTARE
Sex, Gender, and Epigenetics: From Molecule to Bedside explores our expanding knowledge of the science of epigenetics in which gene expression is modified as a consequence of small chemical additions to various components of the genome. The book provides an overview of the field, describing the epigenetic phenomena that unite biological sex and environmental experience to create the unique phenome of each individual. The book also analyzes the impact of ancestors’ environmental experience on subsequent generations through the sex-specific transmission of environmentally induced epigenetic modifications.
Here, international leaders in the field discuss both sex-specific normal physiology and the experience of disease, with chapters dedicated to fetal programming, the microbiome, cancer, bipolar disorder and schizophrenia, embryogenesis, and oocyte aging, among other topics.
| Table Of Contents: | ||
| 1. Exploring how we become what we are Marianne J. Legato 2. A critical view of the revolution of precision medicine. Genetics, epigenetics, sex, and gender Marek Glezerman, Aaron Ciechanover, and Marianne J. Legato 3. Genetic and epigenetic contributions to female-biased lupus disease: X-chromosome inactivation in immune cells Montserrat C. Anguera 4. Genetic, molecular, and cellular determinations of sex-specific cardiovascular traits Felix Vaura 5. Epigenetics and mental and physical health of children born after ART Dov. Feldberg 6. Epigenetic aspects of male infertility treatment Olena M. Kocur, Stephanie Cheung, Philip Xie, Zev Rosenwaks, and Gianpiero D. Palermo 7. Evidence for assisted reproductive technology associated epigenetic variation in humans Boris Novakovic, Jasmine Dennison, Stephanie Cheng, Mark Green, Sharon Lewis, Jane Halliday, and Richard Saffery 8. Deconvoluting the functional role of DNA methylation in trauma; Implications for epigenetic therapy and prospects of targeted “epigenetic therapy” Gal Warhaftig, Daniel Sapozhnikov, Gal Yadid, and Moshe Szyf 9. Antenatal Origins of Health and Disease—A clinician’s perspective Marek Glezerman 10. Maternal anxiety during pregnancy and the lack of fetal DNA methylation in cord blood Jari M. Lahti 11. DNA methylation and other epigenetic modifications mediating the transgenerational impacts of paternal exposures on offspring phenotypes Coralina Collar-Ferna´ndez, Lucas B. Hoffmann, Katie A. Fennell, Terence Y. Pang, and Anthony J. Hannan 12. Epigenetics and psychiatry Jacob Peedicayil 13. Integrative transcriptomics reveals sexually dimorphic control of the cholinergic/neurokine interface in schizophrenia and bipolar disorder Hermona Soreq 14. Gender specific neurobehavioral and gene expression changes in a valproic acid (VPA)–induced mouse model of autistic like behavior and correction by S-adenosylmethionine (SAMe) Asher Ornoy, Liza Weinstein-Fudim, Maria Becker, Denis Gorobetc, and Moshe Szyf 15. Genetics and epigenetics of the onecarbon metabolism pathway in autism spectrum disorder: Role of a sex-specific brain epigenome Donato Gemmati and Veronica Tisato 16. Novel mechanisms for gene regulation: Chemical tags on RNA molecules Zeenal H. Patel and Ina Anreiter 17. Genes, environments, and epigenetics Mila Gorchkova, Ina Anreiter, and Marla B. Sokolowski 18. Epigenetic mechanisms linking poor maternal nutrition during pregnancy to the cardio-metabolic health of offspring Luciana Pellegrini Pisani and Susan Ozanne 19. Epigenetic aspects of human reproduction and early pregnancy Dov. Feldberg 20. Sex-specific impact of maternal metabolic environment on the development of the offspring, from gametogenesis to infancy and beyond Anne Gabory and Claudine Junien 21. Mitochondria as epigenetic regulators of reproductive aging Keshav K. Singh 22. The fetal programming of telomere biology hypothesis Sonja Entringer 23. Brain organoids modeling of genetic and environmental impact on neurodevelopmental traits Nicolo` Caporale, Sarah Stucchi, Cristina Cheroni, and Giuseppe Testa |
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