Historical Perspective of Scleroderma

Denton, Christopher P. (et al.)

Pages 3-7

Epidemiology, Environmental, and Infectious Risk Factors

Barnes, Jammie K. (et al.)

Pages 11-24

Genetic Factors

Assassi, Shervin (et al.)

Pages 25-38

Disease Subsets in Clinical Practice

Domsic, Robyn T. (et al.)

Pages 39-48

Evolving Concepts of Diagnosis and Classification

Johnson, Sindhu R. (et al.)

Pages 49-64

Overlap Syndromes

Moinzadeh, Pia (et al.)

Pages 65-74

Juvenile Localized and Systemic Scleroderma

Graham, Lauren V. (et al.)

Pages 75-89

Morphea (Localized Scleroderma)

Teske, Noelle M. (et al.)

Pages 91-113

Scleroderma Mimics

Hummers, Laura K. (et al.)

Pages 115-123

Systems Biology Approaches to Understanding the Pathogenesis of Systemic Sclerosis

Mahoney, J. Matthew (et al.)

Pages 125-129

Introduction: The Etiopathogenesis of Systemic Sclerosis – An Integrated Overview

Feghali-Bostwick, Carol (et al.)

Pages 133-139

Pathology of Systemic Sclerosis

Rooper, Lisa M. (et al.)

Pages 141-159

Inflammation and Immunity

Boin, Francesco (et al.)

Pages 161-195

Autoantibodies as Markers and Possible Mediators of Scleroderma Pathogenesis

Maurer, Kimberly Doering (et al.)

Pages 197-205

The Clinical Aspects of Autoantibodies

Kuwana, Masataka (et al.)

Pages 207-220

Mechanisms of Vascular Disease

Manetti, Mirko (et al.)

Pages 221-244

Biomarkers in Systemic Sclerosis

Lafyatis, Robert (et al.)

Pages 245-260

Pathophysiology of Fibrosis in Systemic Sclerosis

Trojanowska, Maria (et al.)

Pages 261-280

Overview of Animal Models

Asano, Yoshihide (et al.)

Pages 281-293

Raynaud’s Phenomenon, Digital Ulcers and Nailfold Capillaroscopy

Herrick, Ariane L. (et al.)

Pages 297-316

Renal Crisis and Other Renal Manifestations of Scleroderma

Denton, Christopher P. (et al.)

Pages 317-330

Cardiac Involvement: Evaluation and Management

Shah, Sanjiv J. (et al.)

Pages 331-356

Overview of Lung Involvement: Diagnosis, Differential Diagnosis and Monitoring

Denton, Christopher P.

Pages 359-362

Clinical Assessment of Lung Disease

Keir, Gregory J. (et al.)

Pages 363-373

Treatment of Interstitial Lung Disease

Brown, Kevin K. (et al.)

Pages 375-383

Pathogenesis of Pulmonary Arterial Hypertension

Tuder, Rubin M. (et al.)

Pages 385-401

Clinical Assessment of Pulmonary Hypertension

Farber, Harrison W. (et al.)

Pages 403-409

The Management of Pulmonary Arterial Hypertension in the Setting of Systemic Sclerosis

Mathai, Stephen C. (et al.)

Pages 411-419

Overview of Gastrointestinal Tract Involvement

Denton, Christopher P.

Pages 423-426

Upper Gastrointestinal Tract: Manifestations of Systemic Sclerosis

Clarke, John O. (et al.)

Pages 427-441

Small and Large Intestinal Involvement and Nutritional Issues

Harrison, Elizabeth (et al.)

Pages 443-458

Calcinosis

Valenzuela, Antonia (et al.)

Pages 461-471

Evaluation and Management of Skin Disease

Sherber, Noëlle S. (et al.)

Pages 473-488

Assessment and Management of Progressive Skin Involvement in Diffuse Scleroderma

Simms, Robert W.

Pages 489-498

Skeletal Muscle Involvement

Mammen, Andrew L.

Pages 499-505

Tendons, Joints, and Bone

Avouac, Jérôme (et al.)

Pages 507-523

Cancer in Systemic Sclerosis

Shah, Ami A. (et al.)

Pages 525-532

Overlooked Manifestations

Lally, Edward V. (et al.)

Pages 533-550

Pregnancy

Chakravarty, Eliza F. (et al.)

Pages 551-561

Introduction to Section VIII: Management and Outcome Assessment

Varga, John (et al.)

Pages 565-566

Immunomodulatory, Immunoablative, and Biologic Therapies

Laar, Jacob M. (et al.)

Pages 567-582

Investigative Approaches to Drug Therapy

Ong, Voon H. (et al.)

Pages 583-594

Drug Development and Regulatory Considerations for SSc Therapies

Wright, Timothy M.

Pages 595-601

Physical and Occupational Therapy

Mouthon, Luc (et al.)

Pages 603-613

Psychosocial Issues and Care for Patients with Systemic Sclerosis

Jewett, Lisa R. (et al.)

Pages 615-621

Clinical Trial Design in Systemic Sclerosis

Suliman, Yossra A. (et al.)

Pages 623-635

Measuring Disease Activity and Outcomes in Clinical Trials

Khanna, Dinesh (et al.)

Pages 637-648

Innovative Approaches to Clinical Trials in Systemic Sclerosis

Dobrota, Rucsandra (et al.)

Pages 649-656

Molecular Stratification by Gene Expression as a Paradigm for Precision Medicine in Systemic Sclerosis

Hinchcliff, Monique (et al.)

Pages 657-670

Managing the Ischemic Finger in Scleroderma

Wigley, Fredrick M.

Pages 673-678

Scleroderma Renal Crisis

Stern, Edward P. (et al.)

Pages 679-682

Rapid Diffuse Skin Disease with Progressive Joint Contractures

Hant, Faye N. (et al.)

Pages 683-690

Management of the Scleroderma Patient with Pulmonary Arterial Hypertension Failing Initial Therapy

Mullin, Christopher J. (et al.)

Pages 691-700

Pseudo-obstruction with Malabsorption and Malnutrition

Clarke, John O.

Pages 701-705

Progressive Interstitial Lung Disease Nonresponse to Cyclophosphamide

Silver, Katherine C. (et al.)

Pages 707-712

Coping with the Disfigurement of Scleroderma: Facial, Skin, and Hand Changes

Gholizadeh, Shadi (et al.)

Pages 713-721

Managing Complicated Digital Ulcers

Spence, Robert J.

Pages 723-730