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Schizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change. The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery. Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change. An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia.
Contents
	Part I Overview
	1 Introduction ............................................................................................. 3
	Philip G. Janicak, Stephen R. Marder, Rajiv Tandon,
	and Morris Goldman
	2 The Evolving Nosology of Schizophrenia:
	Relevance for Treatment ........................................................................ 13
	Rajiv Tandon and Dawn Bruijnzeel
	Part II Recent Research into the Pathophysiology of Schizophrenia
	3 Overview of Neurobiology ...................................................................... 27
	Rajiv Tandon and Morris Goldman
	4 Pathophysiology of Schizophrenia ......................................................... 35
	Jaya Padmanabhan and Matcheri S. Keshavan
	5 Genetics of Schizophrenia ...................................................................... 59
	Alan R. Sanders
	6 Recent Advances in Neuroimaging Biomarkers
	of Schizophrenia ...................................................................................... 71
	Lei Wang and John G. Csernansky
	Part III Medical Management of Schizophrenia
	7 Acute Management of Schizophrenia ................................................... 107
	Philip G. Janicak
	8 Therapeutic Neuromodulation for Treatment
	of Schizophrenia ...................................................................................... 139
	Jeffrey T. Rado and Edgar I. Hernandez
	9 Pharmacogenetics in the Treatment of Schizophrenia ........................ 161
	Bill W. Massey, Jiang Li, and Herbert Y. Meltzer
	10 Management of Comorbid Medical Conditions
	in Schizophrenia ...................................................................................... 175
	Jeffrey T. Rado
	11 Management of Water Imbalance in Schizophrenia ............................ 205
	Morris Goldman and Pichai Ittasakul
	12 Management of Medication-Related Adverse Effects ......................... 225
	Wanlop Atsariyasing and Morris Goldman
	Part IV Management of Schizophrenia and Its Long-Term
	Complications
	13 Long-Term Pharmacological Management of Schizophrenia ............ 265
	Stephen R. Marder
	14 Psychosocial Rehabilitation and Psychotherapy Approaches ............. 275
	Robert S. Kern, William P. Horan, Shirley M. Glynn,
	L. Felice Reddy, Jason Holden, Eric Granholm,
	Luana R. Turner, Mary E. Sullivan, and William D. Spaulding
	Part V Future Directions and Implications
	15 Conclusion ............................................................................................... 315
	Philip G. Janicak, Stephen R. Marder, Rajiv Tandon,
	and Morris Goldman
	Index ................................................................................................................. 321
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