1 Transfusion in the New Millennium

Ennio C. Rossi, Toby L. Simon

Section I. Contemporary Issues in Donation and Transfusion

2 Patient Blood Management

Darrell J. Triulzi, Mark H. Yazer, J.H. Waters

3 Clinical and Technical Aspects of Blood Administration

Eric Gehrie, Jocelyn Chandler, Edward Snyder

4 Recruitment and Screening of Donors and the Collection, Processing, and Testing of Blood

Kendall P. Crookston, Aaron E. Pritchard, Toby L. Simon

5 Adverse Reactions and Iron Deficiency after Blood Donation

Anne F. Eder, Joseph E. Kiss

6 Donor Vigilance and Hemovigilance

Øystein Flesland, Johannna C. Wiersum-Osselton

7 Global Perspective on Ensuring Blood and Blood Product Safety and Availability

Paul D. Mintz, Mark J. Weinstein

Section II. Blood Components and Derivatives

Part I. Red Blood cells

8 Red Blood Cell Production and Kinetics

Mark J. Koury

9 Red Blood Cell Metabolism, Preservation and Oxygen Delivery

John R. Hess, Bjarte G. Solheim

10 Anemia and Red Blood Cell Transfusion

Jeffrey L. Carson, Paul Hébert

11 Sickle Cell Anemia, Thalassemia and Congenital Hemolytic Anemias

Keith Quirolo, Elliott Vichinsky

12 Autoimmune Hemolytic Anemias and Paroxysmal Nocturnal Hemoglobinuria

Andrea M. McGonigle, Paul M. Ness, Karen E. King

13 Carbohydrate Blood Groups

Laura Cooling

14 Rh and LW Blood Groups

Connie M. Westhoff, Don L. Siegel

15 Other Protein Blood Groups

Jill R. Storry

16 Red Cell Immunology and Compatibility Testing

Connie M. Westhoff

Part II: Platelets

17 Platelet Production and Kinetics

Christopher A. Tormey, Henry M. Rinder

18 Platelet Immunology and Alloimmunization

Janice G. McFarland

19 Preparation, Preservation, and Storage of Platelet Concentrates

Ralph R. Vassallo, Jr.

20 Thrombocytopenia and Platelet Transfusion

Mike F. Murphy, Simon Stanworth, Lise Estcourt

21 Management of Immune-Mediated Thrombocytopenia

Donald M. Arnold, Ishac Nazi, James W. Smith, Theodore E. Warkentin

Part III: White Blood Cells

22  Neutrophil Production and Kinetics: Neutropenia and Neutrophilia

Lawrence Rice and Miho Teruya

23 Neutrophil Collection and Transfusion

Ronald G. Strauss

24 Leukocyte-Reduced Blood Components: Laboratory and Clinical Aspects

Tor Hervig, Jerard Segatchian

Part IV Plasma

25 Composition of Plasma

Peter Hellstern

26 Plasma and Cryoprecipitate for Transfusion

Simon J. Stanworth, Alan T. Tinmouth

27 The Purification of Plasma Proteins for Therapeutic Use

Joseph Bertolini

28 Recombinant Products for the Treatment of Hemophilia: Recent Advances

Michael Wilson, Andrew Nash, Iris Jacobs, Arna Andrews

29 Coagulation Factor Concentrates for Inherited Bleeding Disorders

Gary M. Woods, Amy L. Dunn

30 Coagulation Factor Concentrates and Pharmacologic Therapies for Acquired Bleeding Disorders

Neil Shah, Lawrence Tim Goodnough

31  Immunoglobulin Products

Melvin Berger

Section III: Apheresis, Transplantation, and New Therapies

32 Apheresis: Principles and Technology of Hemapheresis

Edwin A. Burgstaler, Jeffrey L. Winters

33 Therapeutic Apheresis

Bruce McLeod, Shanna Morgan, Jeffrey McCullough

34 Therapeutic Phlebotomy and Specialized Hemapheresis

Jeffrey A. Bailey, Robert Weinstein

35 Hematopoietic Growth Factors

David J. Kuter

36 Hematopoietic Stem Cells and Cord Blood

Jeffrey McCullough

37 Hematopoietic Stem Cell Transplantation

Sameh Gaballa, Amin Alousi, Sergio Giralt, Richard Champlin

38 Gene Therapy Applications to Transfusion Medicine

Eric A. Gehrie, Alexey Bersenev, Emanuela Bruscia, Diane Krause, Wade Schulz

39 HLA Antigens and Alleles

Christian Naper, Bjarte G. Solheim

40 Tissue Banking

Ralph M. Powers, Jeanne V. Linden

41 Adoptive Immunotherapy

Sarah M. Drawz, Jeffrey S. Miller, David H. McKenna

42 Tissue Engineering and Regenerative Medicine

Sumati Sundaram, Joshua Siewert, Jenna Balestrini, Ashley Gard, Kevin Boehm, Elise Wilcox, Laura Niklason

Section IV. Specialized Clinical Practice

Part I: Obstetrics and Pediatrics

43 Obstetric Transfusion Practice

Marieke B.Veenhof, Jos J.M. van Roosmalen, Anneke Brand

44 Fetal and Neonatal Hematopoiesis

Robert D. Christensen, Martha C. Sola-Visner

45 Hemolytic Disease of the Fetus and Newborn

Bjarte G. Solheim, Morten Grönn, Thor Willy Ruud Hansen

46 Red Blood Cell Transfusions for Neonates and Infants

Ronald G. Strauss

47 Platelet and Plasma Transfusions for Infants and Children

Jeanne E. Hendrickson, Cassandra D. Josephson

Part II: Surgery and Trauma

48 Perioperative Transfusion Needs

Leanne Clifford, Daryl J. Kor, James R. Stubbs

49 Transfusion Therapy in the Care of Trauma and Burn Patients

John R. Hess, John B. Holcomb, Steven E. Wolf, Michael W. Cripps

Part III: Oncology

50 Transfusion Support for the Oncology Patient

Wade L. Schulz, Edward L. Snyder

Section V. Hazards of Transfusion

Part I: Infectious Hazards

51 Transfusion Transmitted Virus Infections (TTVI)

Erhard Seifried, Michael Schmidt

52 Transfusion Transmission of Parasites

Bryan R. Spencer

53 Bacterial Contamination of Blood Components

Richard J. Benjamin

54 Prion Diseases

Marc L. Turner

55 Testing for Pathogens in Donors

Tho D. Pham, Susan A. Galel

56 Pathogen Reduction of Blood Components and Plasma Derivatives

Nathan J. Roth

Part II: Other Hazards

57 Hemolytic Transfusion Reactions

Robertson D. Davenport, Martin H. Bluth

58 Febrile, Allergic, and Non-immune Transfusion Reactions

Emmanuel Fadeyi, Gregory J. Pomper

59 Transfusion-Related Lung Injury

Ulrich J. Sachs, Jonathan P. Wallis

60 Transfusion-Associated Graft Versus Host Disease

Eric Gehrie, Edward Snyder, Alex Ryder

61 Transfusional Iron Overload

Sujit Sheth

62  Immunomodulatory and Pro-Inlammatory Effects of Allogeneic Blood Transfusion

Eleftherios C. Vamvakas, José O. Bordin, Morris A. Blajchman