Up- to- date evidence from the most recent experimental and clinical trials on resuscitation science
Hot and controversial topics on resuscitation discussed by top experts in the field
Gold standard resuscitation and post- resuscitation treatments and interventions
Resuscitation is a two-stage process comprising the achievement/maintenance of spontaneous circulation and post-resuscitation management. The approach is complex and multifaceted and entails the integration of new physiological insights, pharmacological options, and technological advances. The purpose of this volume, written by top experts in the field, is to promote, share, and disseminate new advances in resuscitation and post-resuscitation care. The issues addressed are wide ranging and of great topical interest or controversy. They include priorities of intervention, quality of resuscitation, use of mechanical supports, new defibrillation strategies, prevention of organ damage, strategies in cases of sudden cardiac death, new pharmacological treatments, and post-resuscitation care, including temperature management and prediction and improvement of outcome after cardiac arrest. Particular attention is devoted to up-to-date evidence from the most recent experimental and clinical trials on resuscitation science and to gold standard evidence-based resuscitation and post-resuscitation treatments and interventions. In addition, organizational models and integrated care systems for trauma are considered, and critical care education and the process of guideline development are reviewed.
Preface.- I State of the Art in Resuscitation.- 1 Resuscitation science: from the beginning to the present day.- 2 From Experimental and Clinical Evidence to Guidelines.- 3 Trauma Systems and Trauma Care.- II Advances on Cardiopulmonary Resuscitation (CPR) and Defibrillation.- 4 Compression only CPR versus CPR with ventilations.- 5 Defibrillation and Resuscitation.- 6 Amplitude Spectrum Area to predict the success of defibrillation and to guide resuscitation interventions.- 7 The importance of automated external defibrillation implementation programs.- III Optimization of Cardiopulmonary and Cerebral Resuscitation on Sudden Cardiac Death.- 8 Manual vs Mechanical Chest Compression.- 9 Optimized Approach in Cardiocerebral Resuscitation.- 10 Reperfusion Strategies in Sudden Cardiac Arrest.- 11 Extracorporeal Membrane Oxygenation (ECMO) Strategy in Cardiac Arrest.- IV Pharmacological Approach during CPR.- 12 Vasopressors during CPR.- 13 Targeting Mitochondria during CPR.- 14 The Potential Contribution of Corticosteroids to Positive Cardiac Arrest Outcomes.- 15 Pharmacological induction of hypothermia.- V Post Resuscitation Care.- 16 Effectiveness of Hypothermia in Human Cardiac Arrest and Update on the Target Temperature Management Trial.- 17 New Strategies to Improve Outcome After Cardiac Arrest.- 18 New methods to induce localized brain and general hypothermia.- 19 Predicting Outcome of Cardiac Arrest.- VI Combining Physiology, Clinical Outcome, and Ethics.- 20 Circulating Cardiac Biomarkers and Outcome.- 21 Circulatory Shock: Definition, Assessment and Management.- 22 Resuscitation and Ethics.