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Induction of the Fetal Scarless Phenotype in Adult Wounds: Impossible?
Pages 3-17
This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addresses muscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties.
"With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction."
- Geoffrey C. Gurtner, MD, FACS
Johnson and Johnson Distinguished Professor of Surgery
Professor (by courtesy) of Bioengineering and Materials Science
Inaugural Vice Chairman of Surgery for Innovation
Stanford University School of Medicine
Induction of the Fetal Scarless Phenotype in Adult Wounds: Impossible?
Pages 3-17
Scar Treatment and Prevention: Know Thine Enemy
Pages 19-26
Challenges and Opportunities in Drug Delivery and Wound Healing
Pages 27-38
Harvesting, Processing, and Injection of Lipoaspirate for Soft-Tissue Reconstruction: Details Make the Difference
Pages 39-43
Adipose Tissue Complex (ATC): Cellular and Biocellular Uses of Stem/Stromal Cells and Matrix in Cosmetic Plastic, Reconstructive Surgery and Regenerative Medicine
Pages 45-69
Preparation, Characterization, and Clinical Implications of Human Decellularized Adipose Tissue Extracellular Matrix
Pages 71-89
Mesenchymal Cells that Support Human Skin Regeneration
Pages 91-107
Stem Cells and Burn
Pages 109-115
Skin Tissue Engineering in Severe Burns: A Review on Its Therapeutic Applications
Pages 117-136
Skin Substitutes for Burn Wounds
Pages 137-146
Wnt Signaling During Cutaneous Wound Healing
Pages 147-155
Drug Delivery Advances for the Regeneration of Aged Skin
Pages 157-164
Innovative Scaffold Solution for Bone Regeneration Made of Beta-Tricalcium Phosphate Granules, Autologous Fibrin Fold, and Peripheral Blood Stem Cells
Pages 167-179
Ordinary and Activated Bone Substitutes
Pages 181-209
Absorbable Bone Substitute Materials Based on Calcium Sulfate as Triggers for Osteoinduction and Osteoconduction
Pages 211-221
Perivascular Progenitor Cells for Bone Regeneration
Pages 223-229
Bone Repair and Regeneration Are Regulated by the Wnt Signaling Pathway
Pages 231-245
Cartilage Tissue Engineering: Role of Mesenchymal Stem Cells, Growth Factors, and Scaffolds
Pages 249-262
Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation
Pages 263-280
Stem Cells and Ear Regeneration
Pages 281-298
Muscle Fiber Regeneration in Long-Term Denervated Muscles: Basics and Clinical Perspectives
Pages 301-309
Rejuvenating Stem Cells to Restore Muscle Regeneration in Aging
Pages 311-324
Silk Fibroin-Decorin Engineered Biologics to Repair Musculofascial Defects
Pages 325-346
Skeletal Muscle Restoration Following Volumetric Muscle Loss: The Therapeutic Effects of a Biologic Surgical Mesh
Pages 347-353
Principles of Tendon Regeneration
Pages 355-367
Stem Cells and Tendon Regeneration
Pages 369-384
Cell Therapies for Tendon: Treatments and Regenerative Medicine
Pages 385-408
Current Trends and Future Perspectives for Peripheral Nerve Regeneration
Pages 411-423
The Regeneration of Peripheral Nerves Depends on Repair Schwann Cells
Pages 425-435
Adipose-Derived Stem Cells (ASCs) for Peripheral Nerve Regeneration
Pages 437-446
Direct Reprogramming Somatic Cells into Functional Neurons: A New Approach to Engineering Neural Tissue In Vitro and In Vivo
Pages 447-462
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