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The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.
Contents
1 The Lung in Rheumatic Diseases................................................. 1
Paul F. Dellaripa and Kevin R. Flaherty
2 Evaluation of Lung Disease in Patients
with Connective Tissue Disease..................................................... 13
Aryeh Fischer and Kevin K. Brown
3 Rheumatoid Arthritis..................................................................... 25
Jay H. Ryu and Eric L. Matteson
4 Interstitial Lung Disease in Systemic Sclerosis........................... 37
Nargues Weir and Virginia Steen
5 Inflammatory Myopathy/Anti synthetase
Syndrome................. 49
Cheilonda Johnson, Chester V. Oddis, and Sonye K. Danoff
6 Pulmonary Manifestations of Systemic
Lupus Erythematosus (SLE)......................................................... 61
Shikha Mittoo and Jeffrey J. Swigris
7 Pulmonary Manifestations in Mixed Connective
Tissue Disease................................................................................. 73
Kristin B. Highland and Richard M. Silver
8 Pulmonary Manifestations of Primary
Sjögren’s Syndrome....................................................................... 83
Tracy R. Luckhardt and Barri J. Fessler
9 Pulmonary Manifestations of Sarcoidosis................................... 95
Kristin B. Highland and Daniel A. Culver
10 Pulmonary Manifestations of Vasculitis....................................... 123
Ulrich Specks
11 Pulmonary Hypertension Associated with Connective
Tissue Disease................................................................................. 139
Stephen C. Mathai and Laura K. Hummers
12 Respiratory Infections in the Rheumatic Disease Patient.......... 167
Jonathan B. Parr, Ritu R. Gill, and Joel T. Katz
13 Lung Transplantation for Connective Tissue
Disease-Associated
Lung Disease.................................................. 179
Ryan Hadley and Kevin M. Chan
14 Current and Emerging Treatment Options
in Interstitial Lung Disease........................................................... 193
Toby M. Maher
Index........................................................................................................ 217
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