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Discovery of the Proton and Its Intrinsic Powers
Pages 3-8
This book offers a comprehensive, practical guide to understanding the physical and biological characteristics of proton beam radiotherapy. The application of proton beams to the treatment of solid cancers has expanded exponentially over the last decade due to their physical properties, which make it possible to administer higher doses of radiation to lesions with only a minimum dose to the surrounding healthy tissues. Accordingly, understanding the basic aspects of proton beam radiotherapy is a primary concern not only for medical physicists and radiation biologists, but also for all physicians involved in cancer treatment using proton beams.
The major aspects discussed include the technique’s development background, the generation and delivery system for proton beams, physical characteristics, biological consequences, dosimetry, and future prospects in both medical physics and radiation biology in terms of effective cancer treatment. Gathering contributions from experts who provide clear and detailed information on the basics of proton beams, the book will greatly benefit not only radiological technicians, medical physicists, and physicians, but also scientists in cancer radiotherapy.
Discovery of the Proton and Its Intrinsic Powers
Pages 3-8
Early History of Biology and Clinical Application of Proton Beam Therapy
Pages 9-21
The Current Status of Proton Beam Therapy
Pages 23-33
Physical Characteristics of Proton Beams
Pages 37-50
Dosimetry of Proton Beams
Pages 51-60
Track Structure and Microdosimetry of Proton Beams
Pages 61-72
Qualitative Comparison of Proton Beams and Other Radiotherapy Beams
Pages 73-82
Accelerator Systems for Proton Radiotherapy
Pages 85-96
Beam Delivery System for Proton Radiotherapy
Pages 97-112
Treatment Planning System for Proton Radiotherapy
Pages 113-125
Motion Management
Pages 127-138
Quality Assurance for Proton Beam Radiotherapy
Pages 139-158
Current Topics of Proton Radiobiology
Pages 161-169
Energy Deposition of Proton Beams in Cells
Pages 171-182
DNA Damage, Repair Mechanisms, and Chromosomal Aberrations
Pages 183-208
Relative Biological Effectiveness and Fractionation of Proton-Beam Therapy
Pages 209-222
Technological Developing Issues and the Future of Proton Beam Therapy
Pages 225-235
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