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This book provides a comprehensive overview of the management of brain and skull base tumors. It features detailed insight into the intrinsic molecular biology, anatomical foundation, radiological planning, surgical execution, and the novel therapeutics that guide today’s treatment regimens. The first section features concepts related to the epidemiology and pathological basis of disease processes, including relevant cellular and molecular biology. In the second section, integral anatomical foundations and principles are covered including microsurgical anatomy of the cerebrum, white matter tracts, ventricles, brainstem, skull base, advancements in radiological imaging, and cognitive examinations. Surgical approaches and how to execute these procedures are then subsequently discussed in the third part of the work.
Principles of Neuro-Oncology: Brain & Skull Base is a practically applicable guide to the latest treatment techniques available to treat these patients. Therefore, it is an indispensable resource for all physicians who utilize these methodologies in their day-to-day practice.
History of Neuro-Oncology: Towards a New Frontier
Pages 1-14
Garza-Salazar, Jaime G. (et al.)
Epidemiology of Brain Tumors
Pages 15-25
Reynoso-Noverón, Nancy (et al.)
Tumor Microenvironment: Comparison Between Primary Origin Tumors and Corresponding Brain Metastasis
Pages 27-41
Cacho-Díaz, Bernardo (et al.)
Diagnostic, Prognostic and Predictive Biomarkers in Gliomas
Pages 43-73
Carlos-Escalante, José Alberto (et al.)
Pathological Classification of Brain Tumors
Pages 75-105
Cano-Valdez, Ana María (et al.)
Gene Therapy in Gliomas
Pages 107-122
Medina-Enríquez, Miriam Marlene (et al.)
Microsurgical Anatomy of the Cranial Base
Pages 123-166
Monroy-Sosa, Alejandro (et al.)
Microsurgical Anatomy of the White Matter Tracts
Pages 167-198
Cortes-Contreras, A. Paula (et al.)
Microsurgical Anatomy of the White Matter Tracts of Brainstem and Cerebellum
Pages 199-223
Alvear-Quito, Nataly Mireya (et al.)
Advancements in fMRI and DTI for Planning Robotically Guided Parafascicular Neurosurgical Trajectories
Pages 225-244
Jennings, Jonathan E. (et al.)
Integration of White Matter Tractography in Subcortical and Skull Base Neurosurgical Planning
Pages 245-264
Fukui, Melanie B. (et al.)
Localization of Brain Tumors
Pages 265-282
Díaz, Bernardo Cacho (et al.)
Neuropsychological Assessment in Brain Tumor Patients
Pages 283-298
Rodríguez-Orozco, Josana
Palliative Care in Brain Tumor
Pages 299-306
Allende-Pérez, Silvia (et al.)
Embolization of Intracranial, Skull Base, Head and Neck Tumors
Pages 307-312
Melo-Guzmán, Gustavo (et al.)
Radiotherapy in Brain Tumors
Pages 313-334
Flores-Castro, Manuel (et al.)
Radiosurgery for Brain Tumors
Pages 335-355
Gutiérrez-Aceves, G. Axayacalt (et al.)
Chemotherapy for Brain Tumors
Pages 357-383
Martínez-Tlahuel, Jorge Luis (et al.)
Local Administration of Therapies and Drug Delivery Strategies for the Treatment of Gliomas
Pages 385-394
Arrieta, Víctor A. (et al.)
Trans-sulcal Parafascicular Surgical Corridor for Resection of Brain Tumors: The Last Frontier
Pages 395-412
Monroy-Sosa, Alejandro (et al.)
Mapping the Brain During Awake Surgery for Patients with Neurological Disorders Including Brain Tumors
Pages 413-436
Ruiz-Garcia, Henry (et al.)
Updates Treatment of Low-Grade Glioma
Pages 437-454
Hervey Jumper, Shawn L. (et al.)
Updated Treatment of Glioblastoma
Pages 455-464
Pérez-Negrete, Isaías (et al.)
Management of Brain Metastases
Pages 465-484
Navarro-Fernández, José Omar (et al.)
Management of Pineal Region Tumors
Pages 485-517
Choque-Velasquez, Joham (et al.)
Anatomy of the Sylvian Fissure: Surgical Applications
Pages 519-537
Longo-Calderón, Gabriel Mauricio (et al.)
Microsurgical Anatomy of the Interhemispheric Fissure Complex: An Anatomical-Functional Model in Brain Tumors
Pages 539-559
Monroy-Sosa, Alejandro (et al.)
Surgical Treatment of Intraventricular Tumors
Pages 561-582
Vigo, Vera (et al.)
Microsurgical Anatomy and Surgical Approaches of the Cranial Base: The Radial Corridors
Pages 583-615
Technological Advances in Neurosurgery
Pages 617-626
Epping, Austin (et al.)
360° Surgical Management of theOrbit and Its Exo-orbital Projections
Pages 627-654
Chakravarthi, Srikant S. (et al.)
A Surgical Corridor for the Craniocervical Junction: A 360-Degree View
Pages 655-663
Barges-Coll, Juan (et al.)
Transfacial Approaches of the Ventral Cranial Base, Paranasal Sinuses, and the Extra Cranial Fossae
Pages 665-683
García, Martín Granados (et al.)
Craniofacial Approach
Pages 685-703
Sanchez-Correa, Thalia (et al.)
Endoscopic Surgery of the Anterior Cranial Base
Pages 705-719
Perez de San Roman Mena, Laila (et al.)
Endonasal Endoscopic Approach of the Sellar and Parasellar Region
Pages 721-743
Salgado López, Laura (et al.)
Endonasal Endoscopic Approach of the Upper, Middle, and Lower Clivus
Pages 745-766
Sangrador Deitos, Marcos Vinicius (et al.)
Endonoasal Endoscopic Approach of the Pterygopalatine Fossa
Pages 767-781
Glicksman, Jeffrey (et al.)
Expanded Endonasal Approach to Meckel’s Diverticulum
Pages 783-796
Chakravarthi, Srikant S. (et al.)
Endoscopic Endonasal Far Medial Approach
Pages 797-815
Requena Requena, Luis C. (et al.)
Surgery of the Anterior Cranial Base: Open Approach
Pages 817-844
Serrato-Avila, Juan Leonardo (et al.)
Surgery for Tumors of the Middle Cranial Base
Pages 845-870
Enrique, Lopez Berumen (et al.)
Temporal Bone: Posterior Petrosectomy
Pages 871-886
Lemus-Rodríguez, Yazmín (et al.)
Surgical Treatment of the Tumors of the Cerebellopontine Angle
Pages 887-908
Landeiro, José Alberto (et al.)
Surgical Treatment of the Tumors of the Jugular Foramen
Pages 909-931
Cândido, Duarte Nuno Crispim (et al.)
Surgical Treatment of Foramen Magnum Tumors
Pages 933-948
Campero, Alvaro (et al.)
Surgery of the Infratemporal Fossa and Parapharyngeal Space
Pages 949-962
Guinto, Gerardo (et al.)
Safe Entry Zones for Brainstem Cavernomas
Pages 963-977
Nathal, Edgar
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