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Risk Factors for Preeclampsia
Pages 3-25
This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy, especially preeclampsia, in both the basic and clinical aspects.
Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality. The pathophysiology of pregnancy-specific disorders was long unknown, but recently many new findings have been reported from the point of view of pathophysiology. Furthermore, this complication of pregnancy, especially preeclampsia, is a potent risk factor for chronic conditions such as cardiovascular disease, diabetes mellitus, kidney disease, and hypertension.
The book is composed of seven parts including genetic background, pathology, pathophysiology, and the latest prediction and treatment of preeclampsia. Specific basic topics such as immunological maladaptation, placental adenosine signaling, and new prediction markers are also expounded by experts. Thus it benefits not only obstetricians, pediatricians, nephrologists, diabetologists, and cardiologists, but also immunologists, endocrinologists, geneticists, pathologists, biologists, and molecular biologists who are interested in the treatment of hypertension in pregnancy.
Risk Factors for Preeclampsia
Pages 3-25
Genetic Background of Preeclampsia
Pages 29-43
Trophoblast Invasion: Remodelling of Spiral Arteries and Beyond
Pages 47-62
Immunological Maladaptation
Pages 65-84
Glucose Intolerance and Insulin Resistance: Relevance in Preeclampsia
Pages 85-98
Placental Adenosine Signaling in the Pathophysiology of Preeclampsia
Pages 99-112
Obesity, Adipokines, and Lipokines
Pages 113-124
Autophagy in Preeclampsia
Pages 125-140
Animal Models in Preeclampsia
Pages 141-155
The Differences Between Early- and Late-Onset Pre-eclampsia
Pages 157-172
sFlt-1/PLGF
Pages 175-198
Ambulatory Blood Pressure Measurement and Home Blood Pressure Measurement
Pages 199-208
MicroRNA
Pages 209-224
Novel Therapies for Preeclampsia
Pages 227-237
Pravastatin for Preeclampsia Prevention and Treatment
Pages 239-251
Prevention and Treatment of Stroke and Eclampsia
Pages 253-270
Cardiovascular Disease Following Hypertensive Pregnancy
Pages 273-290
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