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Precision Cancer Medicine
Role of the Pathologist
Jasani, Huss, Taylor
Editore
Springer
Anno
2022
Pagine
237
ISBN
9783030840860
140,00 €

DA SCONTARE

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

This book describes the changing role of pathology in aiding reproducible and accurate patient selection for predictive cancer therapy. Particular attention is given to the clinical application of cutting-edge cancer biomarkers to accurately select patients for targeted cancer therapy and how artificial intelligence can improve the precision of treatments. The advent and basis of predictive cancer care, the role of pathologists in translational cancer research, the analysis of cancer samples, the management of biopsy results, and the accuracy of biopsy results are also discussed.

 

Precision Cancer Medicine: Role of the Pathologist details how pathologists can use the latest biomarkers and apply artificial intelligence technology in cancer diagnosis and management. It is also relevant to oncologists and medical practitioners involved in cancer management seeking an up-to-date resource on the topic.

  1. Front Matter

    Pages i-xv

    PDF

  2. The Evolution of Pathology and Precision Medicine

    1. Front Matter

      Pages 1-1

      PDF

    2. Introduction: From ‘Tissue Diagnosis’ to Biomarkers

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 3-8

    3. The Advent of Biomarker Testing

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 9-18

    4. The Practical Challenges for Pathology: Multiple Rapidly Evolving Methods

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 19-31

  3. Precision Medicine Demands Precision Pathology

    1. Front Matter

      Pages 33-33

      PDF

    2. Evolution of the Total Test Approach to Tissue Based Pathological Analysis

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 35-42

    3. Pre-Analytic Phase: Test Selection; Specimen Acquisition and Handling

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 43-49

    4. Pre-Analytic Phase: Specimen Type and Acquisition

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 51-54

    5. Pre-Analytical Phase: Biopsy/Tissue Handling and Processing

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 55-67

    6. Analytical Phase: Protocol and Antigen Retrieval

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 69-76

    7. Analytical Phase: Principles for Immunohistochemistry (IHC)

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 77-88

    8. Analytical Phase: Current Controls; Fit for Purpose Selection and Validation

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 89-100

    9. Analytical Phase: Alternative and New Control Systems

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 101-114

    10. Post-Analytic Phase: Interpretation, Scoring and Reporting of Biopsy Results

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 115-124

    11. Description and Interpretation of Results; The Pathology Report

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 125-136

    12. Immunofluorescence, In Situ Hybridization and Alternative Forms of ‘Labeled’ Microscopy

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 137-152

  4. Role of the Pathologist in Predictive Biomarker Analysis

    1. Front Matter

      Pages 153-153

      PDF

    2. Implementation of Precision Cancer Diagnostic Test

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 155-167

    3. Role of Pathologist in Precision Cancer Diagnosis

      • Bharat Jasani, Ralf Huss, Clive R. Taylor

      Pages 169-181

    4. Role of the Pathologist in Predictive Biomarker Analysis

      1. Role of Pathologist in Precision Molecular and Digital Image Analyses

        • Bharat Jasani, Ralf Huss, Clive R. Taylor

        Pages 183-195

    5. Digital and Computational Pathology and Their Role in Precision Oncology

      1. Front Matter

        Pages 197-197

        PDF

      2. Introduction to Digital and Computational Pathology

        • Bharat Jasani, Ralf Huss, Clive R. Taylor

        Pages 199-203

      3. AI in the Pre-Analytical Phase

        • Bharat Jasani, Ralf Huss, Clive R. Taylor

        Pages 205-210

      4. AI in the Analytical Phase

        • Bharat Jasani, Ralf Huss, Clive R. Taylor

        Pages 211-215

      5. AI in the Post-Analytical Phase

        • Bharat Jasani, Ralf Huss, Clive R. Taylor

        Pages 217-223

      6. AI in the Decision Phase

        • Bharat Jasani, Ralf Huss, Clive R. Taylor

        Pages 225-232

    6. Back Matter

      Pages 233-237

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