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Nuclear Medicine is a diagnostic modality which aims to image and in some cases quantify physiological processes in the body to highlight disease or injury. Within nuclear medicine, over the past few decades, major technological changes have occurred and concomitantly changes in the knowledge and skills required have had to evolve. One of the most significant technological changes has been the fusion of imaging technologies, to create hybrid systems such as SPECT/CT, PET/CT and PET/MR. With these changes in mind, Practical SPECT/CT in Nuclear Medicine provides a handy and informative guide to the purchase, clinical implementation and routine use of a SPECT/CT scanner. Practical SPECT/CT in Nuclear Medicine will be a valuable resource for all personnel working in nuclear medicine and it will be of particular value to trainees.
Contents
Part I Scientific Principles
1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Peter Hogg
2 Basic Discussion on Electromagnetic Radiation:
Gamma Radiation in Relation to SPECT Imaging. . . . . . . . . . . . . . . 19
Richard S. Lawson
3 Basic Discussion on Electromagnetic Radiation:
X-Rays in Relation to SPECT/CT Systems . . . . . . . . . . . . . . . . . . . . . 35
Peter Hiles
4 Gamma Camera SPECT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
Richard S. Lawson
5 Computed Tomography: Physical Principles, Instrumentation,
and Quality Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77
Euclid Seeram and Joanne Sil
Part II Selection and Design
6 Selecting an Appropriate SPECT/CT Scanner . . . . . . . . . . . . . . . . . . 111
Julian MacDonald, Marc Griffiths, and David Wyn Jones
7 Design of a Suitable Facility to House a SPECT/CT Scanner . . . . . . 147
David Wyn Jones, Julian MacDonald, and Peter Hiles
Part III Clinical SPECT/CT
8 Clinical Utility (Applications) of SPECT/CT . . . . . . . . . . . . . . . . . . . 165
Tom Kane, Randeep Kulshrestha, Alp Notghi, and Mark Elias
xiv Contents
Part IV Radiation Protection
9 Practical Radiation Dose and Practical Radiation Protection
Considerations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 229
Joanne Sil and Euclid Seeram
10 Optimal Utilization of Imaging Parameters in CT Scanning:
Uses of CT in Radionuclide Imaging – Different Manufacturer
Approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 239
Lynn Bateman and Joanne Sil
Part V Imaging Principles
11 Cross-Sectional Anatomy in Multi-Planar Imaging . . . . . . . . . . . . . . 271
John M. Delieu and Joanne Sil
12 Radiological Contrast Media and Injector Systems . . . . . . . . . . . . . . 287
Jonathan Priestley and Joanne Sil
13 Practical Considerations for Performing Clinical SPECT/CT:
Nuclear Cardiology; Respiratory; Oncology; Neuroendocrine;
Infection; Trauma/Musculoskeletal; Neurological; Miscellaneous
Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299
David Wyn Jones, Marc Griffiths, and Diane Kenwrick
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337
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