Titolo: Polycystic Kidney Disease

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Polycystic Kidney Disease

Translating Mechanisms into Therapy

Editore

Springer

Anno

2018

Pagine

273

ISBN

9781493977826

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD’s clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Authored by experts in the field, this book provides the clinician and researcher with critical information on basic and translational science and clinical approaches in one concise resource.

Classical Polycystic Kidney Disease: Gene Structures and Mutations and Protein Structures and Functions

Cornec-Le Gall, Emilie, MD, PhD (et al.)

Pages 3-26
Bardet-Biedl Syndrome

Liu, Yangfan P., PhD (et al.)

Pages 27-50
Cystic Kidney Diseases Associated with Increased Cancer Risk: Tuberous Sclerosis Complex, Von Hippel-Lindau, and Birt-Hogg-Dubé

Bissler, John J., MD, FAAP, FASN

Pages 51-66
Aberrant Cellular Pathways in PKD

Grazioli, Alison, MD (et al.)

Pages 69-86
Cilia and Polycystic Kidney Disease

Landis, Dawn E., PhD (et al.)

Pages 87-110

The Role of Inflammation and Fibrosis in Cystic Kidney Disease

Harms, James C., MD (et al.)

Pages 111-129
Imaging-Based Diagnosis of Autosomal Dominant Polycystic Kidney Disease

Hwang, Young-Hwan, MD, PhD (et al.)

Pages 133-142
Renal Structural Involvement in Autosomal Dominant Polycystic Kidney Disease: Cyst Growth and Total Kidney Volume – Lessons from the Consortium for Radiologic Imaging of Polycystic Kidney Disease (CRISP)

Rahbari-Oskoui, Frederic, MD, MS (et al.)

Pages 143-153
Renal Complications: Pain, Infection, and Nephrolithiasis

Riella, Cristian, MD (et al.)

Pages 155-169
Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease: Polycystic Liver Disease

Chebib, Fouad T., MD (et al.)

Pages 171-195
Other Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease

Edelstein, Charles L., MD, PhD, FAHA

Pages 197-206
Role of Renin-Angiotensin-Aldosterone System Inhibition in Autosomal Dominant Polycystic Kidney Disease

Garimella, Pranav S., MD, MPH (et al.)

Pages 209-218
Vasopressin Receptor Antagonism in PKD

Irazabal, Maria V., MD (et al.)

Pages 219-227
End-Stage Renal Disease in Patients with Autosomal Dominant Polycystic Kidney Disease

Khunaizi, Ahd (et al.)

Pages 229-241
Management of ADPKD Today

Perrone, Ronald D., MD (et al.)

Pages 243-262