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The Sebaceous Gland Through the Centuries: A Difficult Path to Independence
Pages 3-8
This book, written by experts from across the world, provides comprehensive coverage of acne and rosacea, focusing in particular on pathogenesis and treatment but also considering clinical aspects, prognostic factors, and impacts on quality of life. Both standard knowledge and important, clinically relevant insights that have emerged over the past decade are presented with the goal of assisting the reader in understanding these diseases and improving treatment outcome. It is explained how high-level research has recently given rise to a variety of new concepts in etiology and treatment, and emerging trends are also discussed. The book is in a reader-friendly format that highlights core messages with a very practical and clinical focus. Pathogenesis and Treatment of Acne and Rosacea will be an indispensable reference for all physicians who care for patients with acne or rosacea and for scientists working in the field.
The Sebaceous Gland Through the Centuries: A Difficult Path to Independence
Pages 3-8
Embryology of the Pilosebaceous Unit
Pages 9-17
Molecular Aspects of Sebaceous Differentiation
Pages 19-26
Anatomy of the Sebaceous Gland
Pages 27-31
Sebum and Sebaceous Lipids
Pages 33-41
Experimental Models of the Sebaceous Gland
Pages 43-49
Acne Epidemiology and Socioeconomic Aspects
Pages 53-57
Acne Pathogenesis: What We Have Learned Over the Years
Pages 61-70
The Role of Hyperkeratinization
Pages 71-76
The Role of the Sebaceous Gland
Pages 77-90
The Role of Bacteria
Pages 91-96
Inflammation in Acne
Pages 97-101
A New Concept of Acne Pathogenesis
Pages 105-107
Acne and Genetics
Pages 109-130
Acne and Androgens
Pages 131-134
Acne and Inflammation
Pages 135-141
Acne and Neuropeptides
Pages 143-150
Acne and Bacteria
Pages 151-153
The Acne Biofilm
Pages 155-159
The Evidence Supporting a Link Between Acne and Nutrition
Pages 161-166
Acne and Smoking
Pages 167-169
Antimicrobial Peptides in Acne
Pages 171-178
Acne and Antimicrobial Lipids
Pages 179-183
Natural and Artificial Suntanning
Pages 185-188
Acne and Environmental Pollution (Chloracne)
Pages 189-194
Myths and Beliefs of Acne Pathogenesis: Diet, Smoking, Hygiene
Pages 195-205
Understanding Acne as a Chronic Disease
Pages 209-211
Clinical Aspects of Acne Vulgaris
Pages 213-221
Clinical Aspects of Acne Fulminans
Pages 223-226
Childhood Acne
Pages 227-234
Congenital Adrenal Hyperplasia and Acne in the Male Patients
Pages 235-241
Adult Acne
Pages 243-249
Drug-Induced Acne
Pages 251-257
Body-Builder Acne
Pages 259-263
Acne Cosmetica
Pages 265-270
Acne in Persons with Dark Skin
Pages 271-275
Acne and Heredity
Pages 279-282
Acne Neonatorum
Pages 283-289
Serum Androgens
Pages 291-294
Body Mass Index
Pages 295-297
Sebum Secretion, Skin Type, and pH
Pages 299-303
Lipids in Serum and Sebum
Pages 305-313
The Leeds Acne Grading Technique
Pages 317-324
Evaluation of Clinical Severity by Acne Grading and Lesion Counting
Pages 325-330
Modern Technology for Imaging and Evaluation of Acne Lesions
Pages 331-340
Acne and Congenital Adrenal Hyperplasia
Pages 343-348
The Acne Genes
Pages 349-354
Vitamins and the Skin
Pages 355-361
Urinary Hormone Analysis in Acne
Pages 363-368
Laboratory Evaluations in Acne
Pages 369-375
Evidenced-Based Treatment of Acne
Pages 379-382
The Difficult Acne Patient
Pages 383-388
Improving Compliance with Acne Therapy
Pages 389-395
Keratolytic Treatment
Pages 397-414
Topical Antibiotics
Pages 415-418
Benzoyl Peroxide
Pages 419-423
Topical Retinoids
Pages 425-433
Azelaic Acid
Pages 435-440
Emerging Acne Treatments
Pages 441-447
Oral Antibiotics
Pages 449-458
The Antibiotic Resistance in Acne
Pages 459-464
Prescribing Oral Isotretinoin: The European Approach
Pages 465-469
Oral Isotretinoin: The US Approach
Pages 471-475
Hormonal Therapy for Acne
Pages 477-482
Less Common Treatments
Pages 483-489
Risk Factors of Acne Relapse
Pages 491-495
Acne Maintenance Therapy
Pages 497-502
Cosmetics and Cleansers in Acne
Pages 503-509
Chemical Peeling in Acne
Pages 511-517
Lasers and Phototherapy in Acne
Pages 519-526
Treatment of Acne Scarring
Pages 527-536
Concepts of Future Acne Treatment
Pages 537-542
Acne and Quality of Life
Pages 545-549
Instruments of Measurement of Quality of Life in Acne
Pages 551-560
The SAHA Syndrome
Pages 563-567
The Polycystic Ovary Syndrome and Acne
Pages 569-577
The SAPHO Syndrome
Pages 579-584
The PAPA Syndrome
Pages 585-590
Acne in Transplantation Patients
Pages 591-602
Rosacea: The State of the Art
Pages 605-609
The Vascular Concept
Pages 611-619
Rosacea and Neuropeptides
Pages 621-626
Rosacea and
Pages 627-639
The Role of Adenosine Triphosphate in the Pathogenesis of Rosacea: An Explanation for the Mode of Action of Tetracyclines for the Treatment of Rosacea
Pages 641-643
Standard Grading System for Rosacea
Pages 647-651
Classical Clinical Presentations of Rosacea
Pages 653-659
Rhinophyma: A Variation of Rosacea?
Pages 661-664
Ocular Rosacea
Pages 665-667
Childhood Rosacea
Pages 669-672
Differential Diagnosis of Rosacea
Pages 673-679
A Treatment Strategy for Rosacea
Pages 683-692
Topical Treatment of Rosacea
Pages 693-698
Systemic Treatment of Rosacea
Pages 699-705
Laser and Light Therapy of Rosacea
Pages 707-711
Nonclassical Treatments
Pages 713-717
Cosmetics in Rosacea
Pages 719-727
Treatment of Rhinophyma
Pages 729-731
The Future of Rosacea Treatment
Pages 733-739
Impact of Rosacea on Quality of Life
Pages 743-747
Erratum
Pages E1-E1
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