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Clinical Research in France, Europe, and in the World Dedicated to Ovarian Cancers
Pages 3-12
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Ovarian Cancers
Advances through International Research Cooperation (GINECO, ENGOT, GCIG)
Pujade-Lauraine, Ray-Coquard, Lécuru
Editore
Springer
Anno
2017
Pagine
286
ISBN
9783319321080
110,00 €
DA SCONTARE
This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment, but its ultimate goal and the standard surgical procedure have evolved, giving rise to the question of how to label expert centers for debulking surgery. Neo-adjuvant chemotherapy is becoming more popular and is also a new field for testing novel drug combinations.
Over recent years, ovarian cancer management has embraced molecular biology. It is now more correct to talk about cancers of the ovary rather than ovarian cancer, since it is not a unique disease but several entities with different molecular drivers. The significant advances in drugs targeting the microenvironment or the tumor cell DNA repair mechanisms are presented in detail together with exciting future perspectives.
All these advances would not have been possible without collaborative groups such as the GINECO group in France and their integration in wider clinical research networks at the European (ENGOT) and international (GCIG) level.
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Genetics of Ovarian Carcinomas
Pages 13-31
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Debulking Surgery: Interval Debulking Surgery Versus Primary: Pros and Cons on How to Evaluate Quality
Pages 33-42
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How to Evaluate Tumor Burden Before Therapeutic Decision
Pages 43-58
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Value of Lymphadenectomy
Pages 59-65
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Ovarian Cancer and HIPEC: In the Era of Evidence Based Medicine
Pages 67-78
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Oncofertility Applied to Epithelial Ovarian Cancer
Pages 79-94
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First-Line Systemic Therapy (Chemo/Antiangiogenics)
Pages 95-112
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Ovarian Cancer in the Elderly
Pages 113-132
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Treatment at Relapse (Surgery and Systemic Treatments)
Pages 133-142
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The Future in Ovarian Cancer: Advances in Immunotherapies
Pages 143-168
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High-Grade Carcinomas, BRCA Mutations and the Role of PARP Inhibitors
Pages 171-182
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Serous Tumors of Low Malignant Potential and Low-Grade Serous Carcinomas of the Ovary or Peritoneum
Pages 183-200
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Clear Cell Carcinoma
Pages 201-209
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Endometrioid Carcinoma of the Ovary
Pages 211-220
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Mucinous Carcinoma of the Ovary
Pages 221-232
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Gynecological Carcinosarcomas
Pages 233-246
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Malignant Ovarian Germ Cell Tumours: An Overview of Management and Controversies
Pages 247-259
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Ovarian Sex Cord Tumors
Pages 261-279
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Small Cell Carcinoma of the Ovary
Pages 281-286
