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This book brings together information on all aspects of ossification of the posterior longitudinal ligament (OPLL), a hyperostotic condition of the spine that can cause severe neurological deficits. Since the second edition of this book was published in 2006, there have been tremendous advances in the field, and this third edition provides updated information on the disease’s epidemiology, diagnosis and treatment, while also addressing ossification of the ligamentum flavum (OLF) and diffuse idiopathic spinal hyperostosis. As such, it offers a valuable resource for all those who want to gain a deeper understanding of OPLL/OLF and those involved in making decisions about its treatment.
History of Research
Pages 3-6
Okawa, Atsushi
An Overview of Epidemiology and Genetics
Pages 9-12
Inose, Hiroyuki (et al.)
OPLL: Disease Entity, Prevalence, Literature Research, and Growth
Pages 13-21
Fujimori, Takahito
Natural History of Ossification of the Posterior Longitudinal Ligament (OPLL)
Pages 23-32
Matsunaga, Shunji
Overview of Recent Basic Researches on OPLL and OLF
Pages 35-37
Matsumoto, Morio
Histopathological Features of Ossification of the Posterior Longitudinal Ligament
Pages 39-46
Maeda, Shingo (et al.)
Ectopic Ossification of Human Spinal Ligaments Caused by Mesenchymal Stem Cell Abnormalities
Pages 47-54
Furukawa, Ken-Ichi (et al.)
A Short History of the Genetic Study of OPLL
Pages 55-60
Ikegawa, Shiro
Overview of Possible Roles of OPLL-Associated Genes in OPLL Development
Pages 61-64
Saito, Taku
Application of iPS Cell Technology for OPLL
Pages 65-73
Toguchida, Junya
Mechanisms Underlying OPLL Development in Tiptoe Walking (ttw) Mice
Pages 75-79
Miyamoto, Takeshi
In Vivo Tracing of Neural Tracts in Tip-Toe Walking Yoshimura Mice by Diffusion Tensor Tractography
Pages 81-88
Konomi, Tsunehiko (et al.)
Metabolomics Analysis of OPLL Patients
Pages 89-97
Tsuji, Takashi (et al.)
Diagnosis of OPLL and OLF: Overview
Pages 101-112
Yamazaki, Masashi (et al.)
Clinical Manifestation of Cervical OPLL
Pages 113-118
Ozawa, Hiroshi
Three-Dimensional Imaging of Cervical Ossification of the Posterior Longitudinal Ligament
Pages 119-128
Katsumi, Keiichi (et al.)
Clinical Manifestations of Thoracic Ossification of the Posterior Longitudinal Ligament (OPLL) and Ossification of the Ligament Flavum (OLF)
Pages 129-134
Matsuyama, Yukihiro (et al.)
Evaluation of Distribution Patterns of Spinal Ligament Ossification Using Whole-Spine Computed Tomography in Patients with Cervical Ossification of the Posterior Longitudinal Ligament
Pages 135-143
Hirai, Takashi (et al.)
Diagnostic Imaging of Thoracic OPLL and OLF
Pages 145-151
Mori, Kanji
Biomechanics of the Spinal Cord Compression Due to Cervical Ossification of the Posterior Longitudinal Ligament
Pages 153-163
Nishida, Norihiro (et al.)
Surgical Indications and Choice of Surgical Procedure for Cervical Ossification of the Longitudinal Ligament
Pages 167-174
Nagamoto, Yukitaka (et al.)
Overview of Laminoplasty
Pages 175-180
Chiba, Kazuhiro
Open-Door Laminoplasty for Cervical OPLL: Technique, Long-Term Results, and Complications
Pages 181-185
Kawaguchi, Yoshiharu
Double-Door Laminoplasty for Cervical OPLL: Technique, Complications, and Long-Term Results
Pages 187-192
Takeshita, Katsushi
Posterior Decompression and Fusion for Cervical OPLL: Indication and Technique
Pages 193-199
Koda, Masao (et al.)
Anterior Cervical Decompression for Cervical OPLL: Technique, Complications, and Long-Term Results
Pages 201-206
Yoshii, Toshitaka
Surgical Indications and Choice of Surgical Procedure for Thoracic OPLL
Pages 207-212
Ando, Kei (et al.)
Posterior Decompression and Fusion for Thoracic OPLL: Surgical Techniques, Outcomes, Timing, and Complications
Pages 213-224
Imagama, Shiro (et al.)
Anterior Decompression and Fusion for Thoracic OPLL: Transthoracic and Transsternal Approaches
Pages 225-234
Shindo, Shigeo (et al.)
Circumferential Decompression Through Posterior Approach for Thoracic OPLL: Technique and Complications
Pages 235-242
Kato, Satoshi
Surgery for Ossification of the Ligamentum Flavum: Posterior Decompression with or Without Fusion
Pages 243-248
Kaito, Takashi
Computer-Aided Surgery for Ossification of the Spinal Ligaments
Pages 249-256
Sakai, Kenichiro
Surgical Treatment of Thoracic Ossification of the Posterior Longitudinal Ligament: Intraoperative Spinal Cord Monitoring
Pages 257-263
Yoshida, Go (et al.)
Intraoperative Ultrasonography for Patients with Ossification of the Posterior Longitudinal Ligament
Pages 265-278
Banno, Tomohiro (et al.)
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