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Oncolytic Viruses: T-VEC and Others
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n this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals.
Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.
Oncolytic Viruses: T-VEC and Others
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The Impact of the Intestinal Microbiota in Therapeutic Responses Against Cancer
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Peptide-Based Therapeutic Cancer Vaccines
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Cancer Immunosurveillance by Natural Killer Cells and Other Innate Lymphoid Cells
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Innate Immune Receptors in the Regulation of Tumor Immunity
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Side Effects of Cancer Immunotherapy with Checkpoint Inhibitors
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CD8+ T Cells in Immunotherapy, Radiotherapy, and Chemotherapy
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The Secrets of T Cell Polarization
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Tumor-Targeted Antibodies
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IDO/TDO Inhibition in Cancer
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Immunotherapy of Gliomas
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Strategies to Reduce Intratumoral Regulatory T Cells
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Toward Engineered Cells as Transformational and Broadly Available Medicines for the Treatment of Cancer
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Regulatory T Cells: Their Role, Mechanism of Action, and Impact on Cancer
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Current Status of Immuno-Oncology in Hematologic Cancers
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