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This timely and clinically oriented book uniquely addresses the entire spectrum of treatment for severe obesity and diabetes. It thoroughly examines all aspects from robotic surgery to cell therapy, from the latest antidiabetic drugs to endoscopic procedures and devices, from appetite-inhibiting signals and nutrients to gastric arterial embolization. It offers objective and authoritative information for practicing professionals; not only are successful interventions discussed and updated, but cutting-edge and experimental pathways are also anticipated.
Obesity is the foremost nutritional challenge worldwide. Its companion is type-2 diabetes, the most prevalent metabolic disease. Together they represent the diabesity epidemic, which is draining resources, overwhelming healthcare facilities, and impacting life expectancy and quality of life everywhere. No country has been spared, and most medical specialties have been affected. Many books focus on the surgical options for obesity and diabetes, namely bariatric and metabolic operations. Information on the clinical and pharmacological treatment is also available, conveyed by standard texts on internal medicine and endocrinology. Yet endoscopic maneuvers and prostheses, cell therapy for diabetes, and other innovative approaches are hard to come by, as conventional texts overlook such therapies. This timely publication bridges the gaps between all different therapeutic options, also covering advances in the conservative, surgical and parasurgical domains.
This book will appeal to seasoned specialists, students and healthcare professionals in training alike.
Table of Contents
1 The Dual Burden of Obesity and Diabetes: Old Problems
Die Hard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Joel Faintuch and Saloma˜o Faintuch
2 Cost of Obesity Recurrence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Caroline E. Sheppard, Erica L.W. Lester, Kevin A. Whitlock,
Shahzeer Karmali, Daniel W. Birch, and Christopher J. de Gara
3 Recent Trends in Bariatric and Metabolic Surgery . . . . . . . . . . . . 35
Rudolf A. Weiner, Islam A. El-Sayes, and Sylvia R. Weiner
4 Perspectives of Robotic Bariatric Surgery . . . . . . . . . . . . . . . . . . . 69
Almino Cardoso Ramos, Eduardo Lemos de Souza Bastos,
and Keith Chae Kim
5 Sleeve Gastrectomy and Transit Bipartition . . . . . . . . . . . . . . . . . . 89
Se´rgio Santoro, Sidney Klajner, and Renato Sampaio
6 Surgical Options in Type 2 Diabetes . . . . . . . . . . . . . . . . . . . . . . . . 111
Denis Pajecki, Daniel Riccioppo, Flavio Kawamoto,
and Marco Aurelio Santo
7 Endoscopic Therapeutic Options for Type 2 Diabetes . . . . . . . . . . . 131
Eduardo G.H. de Moura, Ivan R.B. Orso, Bruno C. Martins,
and Guilherme S. Lopes
8 Ileal Transposition Surgery: Mechanisms of Weight Loss
and Diabetes Improvements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 143
Prasanth K. Chelikani
9 Left Gastric Artery Embolization to Treat Obesity: Rationale,
Technique, Experimental, and Clinical Studies . . . . . . . . . . . . . . . . 153
Andrew J. Gunn and Rahmi Oklu
10 Pharmacologic Approach to Type 2 Diabetes in Obese Patients . . . 171
Leon E. Litwak, Carla Musso, and Susana Fuentes
11 Peripheral Signals and Food Intake Control . . . . . . . . . . . . . . . . . . 203
Hugo Mendieta Zeron and Julio Ce´sar Te´llez Lopez
12 Appetite: Inhibiting Properties of Proteins . . . . . . . . . . . . . . . . . . . 217
Ana San Gabriel and Daniel Tome
13 Cell Therapy for Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231
Bipasha Bose, Kishore Reddy Katikireddy, and Sudheer Shenoy P
14 Stem Cells Derived Insulin-Secreting Cells for Insulin-Dependent
Diabetes Mellitus: Exploiting Laboratory Discoveries . . . . . . . . . . 257
Shruti Dave
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