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The scope of Neuromuscular Pathology continuous to expand, as evidenced by the numerous multivolume and speciality texts published in recent years. This short textbook provides a complete overview of both clinical and histological aspects of common and rare neuromuscular diseases. The objective is twofold: to provide information about neuromuscular diseases in a simplified, integrated, and rapidly accessible format suited to those initially encountering the discipline, and also to provide a clear approach using simple pictures, tables and algorithms to illustrate histological features in muscle and nerve biopsy.
This volume is conveniently divided into three sections with a total of 30 chapters. The first section deals with basic principles of neuromuscular histology and physiology, processing technique, histochemistry, and laboratory management. The second and third sections deal with neuromuscular diseases that are summarized in a stepwise approach, complemented by algorithms and organized tables.
Neurologists, neuropathologists, trainees and medical students involved in clinical neuroscience and pathology will find this guide of practical benefit in both education and practice.
Contributor List
Preface
Acknowledgment
Abbreviations
Part I: General
1. Muscle and Nerve Histology
2. Muscle and Nerve Fibers Classification
3. Clinical Neurophysiology
4. Neuromuscular Laboratory
5. Chemical Materials Used in the Lab
6. Biopsy Processing Protocol
7. Histochemistry Protocol
8. Genetic Basis Of Neuromuscular Disorders
9. Neuromuscular Final Report
Part II: Muscle
10. Initial Approach in Muscle Biopsy
11. Differential Diagnosis
12. Electron Microscopy
13. Classification of Myopathy
14. Approach to Neuromyopathy
15. Approach to Vacuolar Myopathy
16. Muscular Dystrophy Diseases
17. Inherited Myopathic Diseases
18. Non-Congenital Acquired Myopathies
19. Metabolic Myopathy
20. Inflammatory Myopathy
21. Chronic Denervation Myopathy
22. Axial Myopathy
23. Fasciitis
Part III: Nerve
24. Classification of Neuropathy
25. Diagnostic Approach in Nerve Biopsy
26. Axonal Neuropathy
27. Demyelinating Neuropathy
28. Cellular and Extracellular Abnormalities
29. Inflammatory Demyelination
30. Other Common Peripheral Neuropathies
Index
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