Titolo: Neurodegenerative Diseases

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Neurodegenerative Diseases

Clinical Aspects, Molecular Genetics and Biomarkers

Editore

Springer

Anno

2018

Pagine

407

ISBN

9783319729374

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson’s disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis.

Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.

Genetics and Epigenetics in the Neurodegenerative Disorders of the Central Nervous System

Fenoglio, Chiara

Pages 1-20
Diagnosis of Alzheimer’s Disease Typical and Atypical Forms

Ghezzi, Laura

Pages 21-28
Genetic Complexity of Early-Onset Alzheimer’s Disease

Ghani, Mahdi (et al.)

Pages 29-50
Genetic Risk Factors for Complex Forms of Alzheimer’s Disease

Bellenguez, Céline (et al.)

Pages 51-76
Role of Cerebrovascular Disease in Cognition

Verdelho, Ana

Pages 77-92

Risk Factors and Prevention in Alzheimer’s Disease and Dementia

Grande, Giulia (et al.)

Pages 93-112
Diagnosis of Frontotemporal Dementia

Fumagalli, Giorgio Giulio

Pages 113-121
Autosomal Dominant Frontotemporal Lobar Degeneration: From Genotype to Phenotype

Serpente, Maria (et al.)

Pages 123-145
Genetic Risk Factors for Sporadic Frontotemporal Dementia

Ferrari, Raffaele (et al.)

Pages 147-186
Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Mouse Models

Ittner, Lars M. (et al.)

Pages 187-219
Fluid Biomarkers in Alzheimer’s Disease and Frontotemporal Dementia

Mattsson, Niklas (et al.)

Pages 221-252
Biomarkers for Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Imaging

Bozzali, Marco (et al.)

Pages 253-277
Genotypic and Phenotypic Heterogeneity in Amyotrophic Lateral Sclerosis

Ticozzi, Nicola (et al.)

Pages 279-295
Lewy Body Dementia

Bonanni, L. (et al.)

Pages 297-312
Rare Dementias

Ferrari, Camilla (et al.)

Pages 313-336
Neurodevelopmental and Neurodegenerative Alterations in the Pathophysiology of Schizophrenia: Focus on Neuro-Immuno-Inflammation

Dell’Osso, Bernardo (et al.)

Pages 337-348
Parkinson’s Disease: Contemporary Concepts and Clinical Management

Carvalho, Vanessa (et al.)

Pages 349-378
Neurodegeneration and Multiple Sclerosis

Petzold, Axel

Pages 379-400