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This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care.
Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
Chapter 1
Criteria for Diagnosis & Response
Robert A. Kyle, M. D. and S. Vincent Rajkumar, M. D.
Chapter 2
Detection of M proteins
Jerry A. Katzmann, Ph.D.
Chapter 3
Pathology Of Multiple Myeloma
Dragan Jevremovic, M.D., Ph.D., and William Morice, M.D., Ph.D.
Chapter 4
Pathogenesis of Multiple Myeloma
Marta Chesi, PhD and P. Leif Bergsagel, MD
Chapter 5
Staging of Multiple Myeloma
Vivek Roy, M.D. and Philip R. Greipp, M.D
Chapter 6
Molecular Classification and Risk Stratification
Shaji Kumar, M.D, Rafael Fonseca, M.D., Keith Stewart, MB. ChB.
Chapter 7
Monoclonal Gammopathies of Undetermined Significance and Smoldering Multiple Myeloma
John A. Lust, MD, PhD, Diane F. Jelinek, PhD, Kathleen A. Donovan, PhD
Chapter 8
Treatment of Newly Diagnosed Multiple Myeloma
Shaji K. Kumar, M.D., Steven J Russell, M.D., Ph.D
Chapter 9
Approach to Relapsed Refractory Myeloma
Joseph Mikhael, MD, Shaji Kumar, MD, S. Vincent Rajkumar, MD
Chapter 10
Autologous Stem Cell Transplantation in the Management of Multiple Myeloma
Morie A. Gertz, M.D., M.A.C.P., Craig B. Reeder, M.D
Chapter 11
Allogeneic Stem Cell Transplantation
Martha Q. Lacy M. D.
Chapter 12
New Agents For Multiple Myeloma
Shaji Kumar, M.D., Arleigh McCurdy, M.D.
Chapter 13
Biological Therapy for Multiple Myeloma
Camilo Ayala-Breton, Stephen J Russell, Kah-Whye Peng
Chapter 14
Management of Treatment Complications and Supportive Care
Francis Buadi, MB. ChB and Asher Chanan Khan, MD
Chapter 15
POEMS Syndrome (Takatsuki Syndrome)
Angela Dispenzieri
Chapter 16
SOLITARY PLASMACYTOMA
David Dingli, MD, PhD and Prashant Kapoor, MD
Chapter 17
Myeloma Bone Disease
Matthew T. Drake, MD, Ph.D
Chapter 18
Vertebral Augmentation
Omar Khan, M.D. and David Kallmes, M.D.
Chapter 19
The Role of Radiation Therapy in the Treatment of Multiple Myeloma, Plasmacytoma and Other Plasma Cell Disorders
Prashant Kapoor, M.D., James A. Martenson, M.D
Chapter 20
Neurologic Complications of Myeloma
Chafic Y. Karam M.D., Michelle L. Mauermann M.D
Chapter 21
Myeloma Cast Nephropathy
Nelson Leung, MD
Chapter 22
Amyloidosis
Morie A. Gertz, M.D., Steven R. Zeldenrust, M.D., Ph.D.
Chapter 23
IgM Multiple Myeloma
Steven R. Schuster MD, Joseph Mikhael MD
Chapter 24
Waldenström’s macroglobulinemia
Stephen M. Ansell, Lucy S. Hodge, Suzanne R. Hayman
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