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LIBRERIA STUDIUM
Manual of Molecular and Clinical Laboratory Immunology, 7th Edition
Detrick, Hamilton, Folds
Editore
American Academy of Microbiology
Anno
2006
Pagine
1340
ISBN
9781555813642
Description
Renamed Manual of Molecular and Clinical Laboratory Immunology, the 7th edition of the Manual of Clinical Laboratory Immunology continues the tradition of serving as the guide for laboratory directors. The new edition places substantial emphasis on molecular techniques and introduces new material that reflects the significant advances and developments in the field of clinical immunology. This valuable reference will be of practical use to immunologists and will serve the needs of students, instructors, and practitioners of clinical immunology.
The book provides a concise, up-to-date review of the basic principles underlying clinical procedures, features detailed descriptions of the methodology used, and places special focus on the interpretation of laboratory findings. All existing chapters have been significantly revised and updated in the 7th edition.
The molecular theme is woven throughout the sections, with the first section of the book specifically outlining cutting-edge molecular applications soon to be introduced into the standard immunology laboratory. Timely material is introduced in chapters and sections covering transplantation, monitoring of cytokines and chemokines, multiple applications of flow cytometry, allergic diseases, and cancer.
Table of Contents
- Editorial Board
- Contributors
- Preface
- SECTION A GENERAL METHODS
- VOLUME EDITOR: ROBERT G. HAMILTON
-
SECTION EDITOR: THOMAS A. FLEISHER
- 1 Proteomics and Genomics Methodology in the Clinical Immunology Laboratory
- THOMAS A. FLEISHER
- 2 Introduction to Protein Analysis
- GLEN L. HORTIN AND ALAN T. REMALEY
- 3 Protein Analysis for Diagnostic Applications
- ALAN T. REMALEY AND GLEN L. HORTIN
- 4 Genomics and Chip Technology
- STEPHEN J. CHANOCK
- 5 Introduction to Molecular Methodology
- RAYMOND P. PODZORSKI
- SECTION B IMMUNOGLOBULIN METHODS
- VOLUME EDITOR: ROBERT G. HAMILTON
-
SECTION EDITOR: DAVID F. KEREN
- 6 Introduction
- DAVID F. KEREN
- 7 Immunoglobulin Genes
- THOMAS J. KIPPS
- 8 Immunoglobulin Quantification and Viscosity Measurement
- JEFFREY S. WARREN
- 9 Clinical Indications and Applications of Serum and Urine Protein Electrophoresis
- DAVID F. KEREN AND RICHARD L. HUMPHREY
- 10 Immunochemical Characterization of Immunoglobulins in Serum, Urine, and Cerebrospinal Fluid
- JERRY A. KATZMANN AND ROBERT A. KYLE
- 11 Cryoglobulins, Cryofibrinogenemia, and Pyroglobulins
- PETER D. GOREVIC AND DENNIS GALANAKIS
- SECTION C COMPLEMENT
- VOLUME EDITOR: ROBERT G. HAMILTON
-
SECTION EDITOR: PATRICIA C. GICLAS
- 12 Analysis of Complement in the Clinical Laboratory
- PATRICIA C. GICLAS
- 13 Molecular and Clinical Evaluation of Atypical Hemolytic Uremic Syndrome
- LISA STRAIN, JUDITH A. GOODSHIP, AND TIMOTHY H. J. GOODSHIP
- 14 An Enzyme-Linked Immunosorbent Assay-Based Method for Functional Analysis of the Three Pathways of the Complement System
- M. A. SEELEN, A. ROOS, J. WIESLANDER, AND M. R. DAHA
- 15 Evaluation of the Mannan-Binding Lectin Pathway of Complement Activation
- MIHAELA GADJEVA AND STEFFEN THIEL
- 16 Complement in Transplant Rejection
- WILLIAM M. BALDWIN III
- SECTION D FLOW CYTOMETRY
- VOLUME EDITOR BARBARA DETRICK
-
SECTION EDITOR MAURICE R. G. O’GORMAN
- 17 Introduction
- MAURICE R. G. O’GORMAN
- 18 Flow Cytometry-Based Immunophenotyping Method and Applications
- LANCE HULTIN AND PATRICIA HULTIN
- 19 Nontraditional Clinical Applications: Paroxysmal Nocturnal Hemoglobinuria Testing, Fetal Red Cell Testing, T-Cell Receptor Vβ Analysis, and Platelet Analysis by Flow Cytometry
- JIACHUN X. KUNG AND ERIC D. HSI
- 20 Immunophenotyping of Leukemia and Lymphoma by Flow Cytometry
- BRENT LEE WOOD
- 21 Standardized Flow Cytometry Assays for Enumerating Hematopoietic Stem Cells
- D. ROBERT SUTHERLAND, IAN CHIN-YEE, MICHAEL KEENEY, AND JAN GRATAMA
- 22 Phenotypic Correlates of Genetic Abnormalities in Acute and Chronic Leukemias
- ELISABETH PAIETTA
- 23 Multimeric Major Histocompatibility Complex Reagents for the Detection and Quantitation of Specific T-Cell Populations
- JOHN D. ALTMAN
- 24 In Situ Gene Amplification and Hybridization Assays: Disease Monitoring Applications Using Flow Cytometry
- BRUCE K. PATTERSON
- SECTION E FUNCTIONAL CELLULAR ASSAYS
- VOLUME EDITOR BARBARA DETRICK
-
SECTION EDITOR STEVEN D. DOUGLAS
- 25 Introduction
- STEVEN D. DOUGLAS
- 26 Delayed-Type Hypersensitivity Skin Testing
- THERON MCCORMICK AND WILLIAM T. SHEARER
- 27 Cryopreservation of Peripheral Blood Mononuclear Cells
- ADRIANA WEINBERG
- 28 Methods for Detection of Antigen- Specific T Cells by Enzyme-Linked Immunospot Assay (ELISPOT)
- BARBARA L. SHACKLETT AND DOUGLAS F. NIXON
- 29 Evaluation of the T-Cell Receptor Repertoire
- SAVITA PAHWA
- 30 Molecular Diagnosis of Chronic Granulomatous Disease
- PAUL G. HEYWORTH AND JOHN T. CURNUTTE
- 31 Clinical Evaluation of Myeloid and Monocytic Cell Functions
- MAURICE R. G. O’GORMAN
- 32 Flow Cytometric Detection and Quantification of Apoptotic Cells
- THOMAS W. MCCLOSKEY, BARBARA N. PHENIX, AND SAVITA PAHWA
- 33 Quantification of Recent Thymic Emigrants: T-Cell-Receptor Excision Circles
- PAUL KROGSTAD
- 34 Measurement of NK-Cell Activity in Humans
- THERESA L. WHITESIDE
- 35 Cellular Immune Assays for Evaluation of Vaccine Efficacy
- JOSEPHINE H. COX, MARK DESOUZA, SILVIA RATTO-KIM, GUIDO FERRARI, KENT J. WEINHOLD, AND DEBORAH L. BIRX
- 36 T-Lymphocyte Activation and Cell Signaling
- JEFFREY R. CURRIER
- 37 Functional Assays for B Cells and Antibodies
- MOON H. NAHM AND ROBIN G. LORENZ
- SECTION F CYTOKINES AND CHEMOKINES
- VOLUME EDITOR BARBARA DETRICK
-
SECTION EDITOR JOHN J. HOOKS
- 38 Introduction
- JOHN J. HOOKS
- 39 Multiplex Cytokine Assays
- DANIEL G. REMICK
- 40 Monitoring of Immune Response Using Cytokine Flow Cytometry
- SMITA A. GHANEKAR, HOLDEN T. MAECKER, AND VERNON C. MAINO
- 41 Molecular Analysis of Cytokines and Cytokine Receptors
- NIELS KRUSE AND PETER RIECKMANN
- 42 Chemokine and Chemokine Receptor Analysis
- BENJAMIN D. MEDOFF AND ANDREW D. LUSTER
- 43 Laboratory Monitoring of Cytokine Therapy
- ANDREW R. PACHNER
- SECTION G IMMUNOHISTOLOGY AND IMMUNOPATHOLOGY
- VOLUME EDITOR ROBERT G. HAMILTON
-
SECTION EDITOR RUSSELL H. TOMAR
- 44 Introduction
- RUSSELL H. TOMAR
- 45 Immunohistochemistry: Principles and Advances
- PATRICK C. ROCHE, ERIC D. HSI, AND BOURKE L. FIRFER
- 46 Use of Molecular Biology Methods on Tissues
- SUMAN SETTY, CHUNG-CHE (JEFF) CHANG, AND ANDRÉ A. KAJDACSY-BALLA
- 47 Immunohistochemistry: Diagnostic and Prognostic Applications
- VINOD B. SHIDHAM AND ANDRÉ A. KAJDACSY-BALLA
- 48 Immunofluorescence Methods in the Diagnosis of Renal and Skin Diseases
- A. BERNARD COLLINS, ROBERT B. COLVIN, CARLOS H. NOUSARI, AND GRANT J. ANHALT
- SECTION H INFECTIOUS DISEASES CAUSED BY BACTERIA, MYCOPLASMAS, CHLAMYDIAE, AND RICKETTSIAE
- VOLUME EDITOR JAMES D. FOLDS
-
SECTION EDITOR HARRY E. PRINCE
- 49 Introduction
- HARRY E. PRINCE
- 50 Diagnostic Methods for Group A Streptococcal Infections
- ANITA SHET AND EDWARD KAPLAN
- 51 Immune Responses to Polysaccharide and Conjugate Vaccines
- CARL E. FRASCH
- 52 Corynebacterium diphtheriae and Clostridium tetani: Immune Response and Diagnostic Methods
- MARTHA L. LEPOW AND PATRICIA A. HUGHES
- 53 Immunologic Methods for Diagnosis of Infections Caused by Diarrheagenic Enterobacteriaceae and Vibrionaceae
- MARCELA F. PASETTI, JAMES P. NATARO, AND MYRON M. LEVINE
- 54 Serologic and Molecular Diagnosis of Helicobacter pylori Infection and Eradication
- BRUCE E. DUNN AND SUHAS H. PHADNIS
- 55 Detection of Antibodies to Legionella
- PAUL H. EDELSTEIN
- 56 Immunologic Methods for Diagnosis of Spirochetal Diseases
- VICTORIA POPE, MARY D. ARI, MARTIN E. SCHRIEFER, AND PAUL N. LEVETT
- 57 Lyme Disease: Serologic Assays for Antibodies to Borrelia burgdorferi
- BARBARA J. B. JOHNSON
- 58 Immunological Tests in Tuberculosis and Leprosy
- GRAHAM H. BOTHAMLEY
- 59 Mycoplasma: Immunologic and Molecular Diagnostic Methods
- KEN B. WAITES, MARY B. BROWN, AND JERRY W. SIMECKA
- 60 Chlamydial Infections
- LEE ANN CAMPBELL, CHO-CHOU KUO, AND CHARLOTTE A. GAYDOS
- 61 The Rickettsiaceae, Anaplasmataceae, Bartonellaceae, and Coxiellaceae
- KARIM E. HECHEMY, YASUKO RIKIHISA, KEVIN MACALUSO, ANDREW W. O. BURGESS, BURT E. ANDERSON, AND HERBERT A. THOMPSON
- 62 Serologic and Molecular Tools for Diagnosing Bordetella pertussis Infection
- SCOTT A. HALPERIN
- 63 Bacillus anthracis Detection and Anthrax Diagnosis
- ALEX R. HOFFMASTER AND TANJA POPOVIC
- SECTION I MYCOTIC AND PARASITIC DISEASES
- VOLUME EDITOR ROBERT G. HAMILTON
-
SECTION EDITOR THOMAS B. NUTMAN
- 64 Introduction
- THOMAS B. NUTMAN
- 65 Molecular and Immunological Approaches to the Diagnosis of Parasitic Infections
- MARIANNA WILSON, PETER M. SCHANTZ, AND THOMAS NUTMAN
- 66 Serological and Molecular Diagnosis of Fungal Infections
- MARK D. LINDSLEY, DAVID W. WARNOCK, AND CHRISTINE J. MORRISON
- SECTION J VIRAL DISEASES
- VOLUME EDITOR JAMES D. FOLDS
-
SECTION EDITOR STEVEN C. SPECTER
- 67 Introduction
- STEVEN C. SPECTER
- 68 Rapid Viral Diagnosis
- MARIE LOUISE LANDRY
- 69 Enhanced Detection of Viruses in Cell Cultures
- THOMAS F. SMITH
- 70 Herpes Simplex Virus
- D. SCOTT SCHMID
- 71 Varicella-Zoster Virus
- D. SCOTT SCHMID AND VLADIMIR LOPAREV
- 72 Epstein-Barr Virus
- HAL B. JENSON
- 73 Cytomegalovirus
- KIRSTEN ST. GEORGE, AKI HOJI, AND CHARLES R. RINALDO, JR.
- 74 Human Herpesviruses 6, 7, and 8
- RICHARD L. HODINKA
- 75 Papillomaviruses and Polyomaviruses
- KEERTI V. SHAH AND EUGENE O. MAJOR
- 76 Adenoviruses
- LETA K. CRAWFORD-MIKSZA
- 77 Parvovirus B19
- STANLEY J. NAIDES
- 78 Influenza Viruses
- JACQUELINE M. KATZ, ALEXANDER I. KLIMOV, STEPHEN E. LINDSTROM, AND NANCY J. COX
- 79 Respiratory Syncytial Virus, Human Metapneumovirus, and the Parainfluenza Viruses
- PEDRO A. PIEDRA AND GUY BOIVIN
- 80 Measles and Mumps
- DIANE S. LELAND
- 81 Rubella Virus
- JAMES B. MAHONY
- 82 Enteroviruses
- DAVID SCHNURR
- 83 Viral Hepatitis
- MAURO BENDINELLI, MAURO PISTELLO, GIULIA FREER, MARIALINDA VATTERONI, AND FABRIZIO MAGGI
- 84 Rotaviruses and Noroviruses
- NINGGUO FENG AND SUZANNE M. MATSUI
- 85 Arboviruses
- ROBERT S. LANCIOTTI AND JOHN T. ROEHRIG
- 86 Hantavirus Infections
- BRIAN HJELLE AND STEPHEN A. YOUNG
- 87 Filoviruses and Arenaviruses
- JAMES E. STRONG, ALLEN GROLLA, PETER B. JAHRLING, AND HEINZ FELDMANN
- 88 Rabies Virus
- D. CRAIG HOOPER
- 89 Human T-Cell Lymphotropic Virus Types 1 and 2
- SUSAN B. NYLAND, THOMAS P. LOUGHRAN, AND KENNETH E. UGEN
- 90 Coronavirus Including Severe Acute Respiratory Syndrome (SARS)
- JAMES B. MAHONY AND CHENGSHENG ZHANG
- 91 Poxviruses
- KEVIN L. KAREM AND INGER K. DAMON
- 92 Prion Diagnostics
- STEPHEN DEALLER
- SECTION K HUMAN IMMUNODEFICIENCY VIRUS
- VOLUME EDITOR BARBARA DETRICK
-
SECTION EDITOR MICHAEL W. BASELER
- 93 Introduction
- MICHAEL W. BASELER
- 94 Principles and Procedures of Human Immunodeficiency Virus Serodiagnosis
- ROBIN DEWAR, HELENE HIGHBARGER, RICHARD DAVEY, AND JULIA METCALF
- 95 General Immunologic Evaluation of Patients with Human Immunodeficiency Virus Infection
- RANDY A. STEVENS, RICHARD A. LEMPICKI, VEN NATARAJAN, JEANETTE HIGGINS, JOSEPH W. ADELSBERGER, AND JULIA A. METCALF
- 96 Quantitation of Viremia and Determination of Drug Resistance in Patients with Human Immunodeficiency Virus Infection
- TAREK ELBEIK, HELENE HIGHBARGER, ROBIN DEWAR, VEN NATARAJAN, HIROMI IMAMICHI, AND TOMOZUMI IMAMICHI
- 97 Measurement of T-Cell-Specific Immunity in Patients with Human Immunodeficiency Virus Infection
- RICHARD L. HENGEL, TOMOZUMI IMAMICHI, AND STEPHEN A. MIGUELES
- SECTION L IMMUNODEFICIENCY DISEASES
- VOLUME EDITOR BARBARA DETRICK
-
SECTION EDITOR HOWARD M. LEDERMAN
- 98 The Primary Immunodeficiency Diseases
- HOWARD M. LEDERMAN
- 99 Approach to the Diagnosis of Severe Combined Immunodeficiency
- CHAIM M. ROIFMAN
- 100 Investigation of Signal Transduction Defects
- MELISSA E. ELDER
- 101 Primary Antibody Deficiency Diseases
- MARY ELLEN CONLEY
- 102 Hereditary and Acquired Complement Deficiencies
- PATRICIA C. GICLAS
- 103 Neutropenia and Neutrophil Defects
- STEVEN M. HOLLAND
- SECTION M ALLERGIC DISEASES
- VOLUME EDITOR ROBERT G. HAMILTON
-
SECTION EDITOR SARBJIT SAINI
- 104 Introduction
- SARBJIT SAINI
- 105 Quantification and Standardization of Allergens
- NICOLETTE C. DEVORE AND JAY E. SLATER
- 106 In Vivo Diagnostic Allergy Testing
- DEREK A. DAMIN AND R. STOKES PEEBLES, JR.
- 107 Immunological Methods in the Diagnostic Allergy Clinical and Research Laboratory
- ROBERT G. HAMILTON
- 108 Assay Methods for Measurement of Mediators and Markers of Allergic Inflammation
- JOHN T. SCHROEDER AND SARBJIT SAINI
- 109 Tests for Immunological Reactions to Foods
- DAVID M. FLEISCHER AND ROBERT A. WOOD
- 110 Diagnosis of Hypereosinophilic Syndromes
- AMY D. KLION
- SECTION N SYSTEMIC AUTOIMMUNE DISEASES
- VOLUME EDITOR JAMES D. FOLDS
-
SECTION EDITOR WESTLEY H. REEVES
- 111 Introduction
- WESTLEY H. REEVES
- 112 Immunofluorescent Antinuclear Antibody Tests
- ARTHUR R. BRADWELL, RICHARD G. HUGHES, AND ABID R. KARIM
- 113 Detection of Autoantibodies against Proteins and Ribonucleoproteins by Double Immunodiffusion and Immunoprecipitation
- WESTLEY H. REEVES, MINORU SATOH, ROBERT LYONS, CODY NICHOLS, AND SONALI NARAIN
- 114 Detection of Autoantibodies by Using Immobilized Natural and Recombinant Autoantigens
- EDWARD K. L. CHAN, RUFUS W. BURLINGAME, AND MARVIN J. FRITZLER
- 115 Detection of Anti-DNA Autoantibodies
- TRINH T TRAN AND DAVID S. PISETSKY
- 116 Autoantibody Testing in Rheumatoid Arthritis
- SONALI NARAIN, MEGHAVI KOSBOTH, AND PAULETTE HAHN
- 117 Laboratory Testing for Antibodies Associated with Antiphospholipid Antibody Syndrome
- JOHN L. SCHMITZ
- 118 Antineutrophil Cytoplasm Antibodies (ANCAs) and Strategy for Diagnosing ANCA-Associated Vasculitides
- ALLAN WIIK
- SECTION O ORGAN-LOCALIZED AUTOIMMUNE DISEASES
- VOLUME EDITOR JAMES D. FOLDS
-
SECTION EDITOR C. LYNNE BUREK
- 119 Introduction
- C. LYNNE BUREK
- 120 Endocrinopathies
- C. L. BUREK, P. E. BIGAZZI, N. R. ROSE, M. ZAKARIJA, J. M. MCKENZIE, L. YU, J. WANG, AND G. S. EISENBARTH
- 121 Autoantibodies to Glycolipids in Peripheral Neuropathy
- HUGH J. WILLISON
- 122 Detection of Antimitochondrial Autoantibodies in Primary Biliary Cirrhosis and Liver Kidney Microsomal Antibodies in Autoimmune Hepatitis
- PATRICK S. C. LEUNG, MICHAEL P. MANNS, ROSS L. COPPEL, AND M. ERIC GERSHWIN
- 123 Skin Diseases
- CARLOS H. NOUSARI AND GRANT J. ANHALT
- 124 Cardiovascular Diseases
- J. BRUCE SUNDSTROM, C. LYNNE BUREK, NOEL R. ROSE, AND AFTAB A. ANSARI
- 125 Kidney and Lung Disease Mediated by Anti-Glomerular Basement Membrane Antibodies: Detection by Western Blot Analysis
- A. BERNARD COLLINS AND ROBERT B. COLVIN
- 126 Autoimmunity of Testis, Ovary, and Spermatozoa
- RICHARD A. BRONSON, JULIA LUBORSKY, AND KENNETH S. K. TUNG
- 127 Immunologic Testing for Celiac Disease and Inflammatory Bowel Disease
- JAMES A. GOEKEN
- 128 Autoimmune Thrombocytopenia
- THOMAS S. KICKLER
- 129 Monitoring Autoimmune Reactivity within the Retina
- JOHN J. HOOKS, MARIAN S. CHIN, CHI-CHAO CHAN, AND BARBARA DETRICK
- SECTION P CANCER
- VOLUME EDITOR ROBERT G. HAMILTON
-
SECTION EDITOR MARK RAFFELD
- 130 Introduction
- 131 Immunologic Approaches to Tumor Markers: Assays, Applications, and Discovery
- ALEX J. RAI AND DANIEL W. CHAN
- 132 Malignancies of the Immune System: Use of Immunologic and Molecular Tumor Markers in Classification and Diagnostics
- MARK RAFFELD AND ELAINE S. JAFFE
- 133 Monitoring of Immunologic Therapies
- THERESA L. WHITESIDE
- 134 The Future of Cancer Diagnostics: Proteomics, Immunoproteomics, and Beyond
- MARY E. WINTERS, MARK LOWENTHAL, ANDREW L. FELDMAN, AND LANCE A. LIOTTA
- SECTION Q TRANSPLANTATION IMMUNOLOGY
- VOLUME EDITOR BARBARA DETRICK
-
SECTION EDITOR MARY S. LEFFELL
- 135 Histocompatibility Testing after Fifty Years of Transplantation
- MARY S. LEFFELL
- 136 Molecular Methods: HLA Alleles
- CAROLYN KATOVICH HURLEY, KAI CAO, TING TANG, NORIKO STEINER, ANA M. LAZARO, C. ALAN HOWARD, AND JENNIFER NG
- 137 Evaluation of the Humoral Response in Transplantation
- ANDREA A. ZACHARY, JULIE A. HOUP, RENATO VEGA, KEVIN CHESTERTON, AND DONNA P. LUCAS
- 138 Evaluation of the Cellular Immune Response in Transplantation
- NANCY L. REINSMOEN AND ADRIANA ZEEVI
- 139 Molecular Characterization of Rejection in Solid Organ Transplantation
- CHOLI HARTONO, DARSHANA DADHANIA, AND MANIKKAM SUTHANTHIRAN
- 140 Human Natural Killer Cell Receptors
- DOLLY B. TYAN AND MARY CARRINGTON
- 141 Detecting Chimerism after Blood and Marrow Transplantation
- LEE ANN BAXTER-LOWE
- SECTION R LABORATORY MANAGEMENT
- VOLUME EDITOR JAMES D. FOLDS
-
SECTION EDITOR RONALD J. HARBECK
- 142 Clinical Immunology Laboratory Accreditation, Licensure, and Credentials
- LINDA COOK AND RONALD J. HARBECK
- Author Index
- Subject Index
- Color Plates
