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Epidemiology of Prostate Cancer in Europe: Patterns, Trends and Determinants
Pages 1-27
This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach. The editors are very excited about the outstanding new or updated contributions from the different expert authors.
The opening chapters address basic aspects including epidemiology, pathology, biology, genetics, and chemoprevention. The role of individual and mass screening is carefully appraised, and extensive attention is devoted to diagnosis and clinical work-up by means of recently implemented investigations such as multiparametric MRI and choline PET-CT.
The use of active surveillance is examined in detail. Subsequent chapters discuss the different therapies that may be employed: open and minimally invasive, including robot-assisted, radical prostatectomy, the various forms of radiation treatment, high-intensity focused ultrasound, cryotherapy, hormonal manipulations, chemotherapy, targeted therapies, and immunotherapy. Up-to-date results from practice-changing phase III randomized clinical trials are included and special insights are provided into the interpretation of results and the patient’s perspective.
Epidemiology of Prostate Cancer in Europe: Patterns, Trends and Determinants
Pages 1-27
Chemoprevention
Pages 29-41
Individual and Population-Based Screening
Pages 43-55
Anatomo-pathology
Pages 57-75
Biomarkers for Prostate Cancer
Pages 77-96
The Clinical Genomics of Prostate Cancer
Pages 97-110
Prostate Cancer Imaging: An Ongoing Change of Paradigm
Pages 111-126
Nuclear Medicine (Bone Scan, Choline and PSMA PET/CT)
Pages 127-141
Diagnosis, Clinical Workup, and TNM Classification
Pages 143-159
Active Surveillance for Low Risk Prostate Cancer
Pages 161-170
Open Radical Prostatectomy
Pages 171-180
The Robotic Laparoscopic Radical Prostatectomy
Pages 181-186
Permanent and High Dose Rate Brachytherapy (Technique, Indications, Results, Morbidity)
Pages 187-202
IMRT, Hypofractionated Radiotherapy and Stereotactic Radiotherapy: Technique, Indications, and Results
Pages 203-216
Combination of Androgen Deprivation Therapy and Radiation Therapy for Locally Advanced and Localized Prostate Cancer
Pages 217-230
Postoperative Irradiation: Immediate or Early Delayed?
Pages 231-250
High-Intensity Focused Ultrasound (HIFU) for Prostate Cancer
Pages 251-272
Prostate Cryotherapy
Pages 273-285
Salvage Prostate Brachytherapy for Postradiation Local Failure
Pages 287-302
Follow-Up After Radical Treatments and Relapse
Pages 303-311
First-Line Hormonal Manipulation: Surgical and Medical Castration with LHRH Agonists and Antagonists, Steroids, and Pure Antiandrogens
Pages 313-325
Chemotherapy and Androgen Receptor-Directed Treatment of Castration Resistant Metastatic Prostate Cancer
Pages 327-342
Bone-Targeted Therapies in Prostate Cancer
Pages 343-356
Immunotherapy and Targeted Therapies in Advanced Castration Resistant Prostate Cancer
Pages 357-377
How to Interpret Numeric Results in Publications?
Pages 379-398
Management of Prostate Cancer: EAU Guidelines on Screening, Diagnosis and Local Primary Treatment
Pages 399-411
The Millenium Patients’ Perspective
Pages 413-422
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