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Anatomy and Physiology of the Breast
Pages 1-39
This text is intended as a practical guide for physicians and surgeons who treat diseases of the breast, both benign and malignant. Thus, general surgeons, internists, family practitioners, gynecologists, surgical oncologists, radiation oncologists, and medical oncologists will find this book useful. The management of breast diseases requires a multidisciplinary approach, and this textbook therefore includes the views of a wide range of specialists from throughout the world. Today the treatment of breast diseases is largely predicated on the results of randomized prospective trials. The results of many clinical trials are discussed in detail, and readers will find this book to be a useful guide to the evidence-based treatment of breast diseases.
The revised edition provides a comprehensive update of the previous version of the book. Specifically, it contains 2 new chapters: “Molecular Classification of Breast Cancer” and “Breast Cancer Molecular Testing for Prognosis and Prediction”. In addition, since publication of the previous edition, the results of numerous adjuvant systemic therapy and neo-adjuvant systemic therapy trials have been published, and this edition provides a comprehensive overview of these trials and discusses how they have changed the management of breast cancer. Similarly, there have been, in the last few years, important new developments in the local therapy of breast cancer. This edition discusses these new developments and particularly recent developments and controversies concerning the management of the axilla in patients with primary breast cancer. New guidelines with respect to radiotherapy are also reviewed and discussed. Finally, all chapters in the book are thoroughly revised and updated to provide readers with current understanding of the biology and treatment of breast cancer.
Anatomy and Physiology of the Breast
Pages 1-39
Congenital and Developmental Abnormalities of the Breast
Pages 41-55
Nipple Discharge
Pages 57-72
Mastalgia
Pages 73-79
Management of Common Lactation and Breastfeeding Problems
Pages 81-104
Evaluation of a Breast Mass
Pages 105-123
Breast Cancer Epidemiology
Pages 125-137
Breast Cancer Screening
Pages 139-155
Breast Imaging
Pages 157-178
Premalignant and Malignant Breast Pathology
Pages 179-194
Breast Cancer Molecular Testing for Prognosis and Prediction
Pages 195-202
Molecular Classification of Breast Cancer
Pages 203-219
Ductal Carcinoma In Situ
Pages 221-228
Surgical Considerations in the Management of Primary Invasive Breast Cancer
Pages 229-245
Management of the Axilla
Pages 247-271
Breast Reconstructive Surgery
Pages 273-289
The Role of Radiotherapy in Breast Cancer Management
Pages 291-310
Adjuvant Systemic Treatment for Breast Cancer: An Overview
Pages 311-321
Endocrine Therapy
Pages 323-334
Systemic Therapy
Pages 335-390
HER2-Targeted Therapy
Pages 391-410
Inflammatory and Locally Advanced Breast Cancer
Pages 411-435
Neoadjuvant Systemic Treatment (NST)
Pages 437-449
Metastatic Breast Cancer
Pages 451-474
Estrogen and Breast Cancer in Postmenopausal Women: A Critical Review
Pages 475-482
Estrogen and Cardiac Events with all-cause Mortality. A Critical Review
Pages 483-490
Breast Diseases in Males
Pages 491-517
Breast Cancer in the Older Adult
Pages 519-528
Breast Cancer in Younger Women
Pages 529-564
Psychological Support for the Breast Cancer Patient
Pages 565-573
Management of the Patient with a Genetic Predisposition for Breast Cancer
Pages 575-592
Chemoprevention of Breast Cancer
Pages 593-600
Design, Implementation, and Interpretation of Clinical Trials
Pages 601-635
Structure of Breast Centers
Pages 637-648
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