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Lipoproteins in Diabetes Mellitus 2nd edition
Jenkins, Toth
Editore
Springer
Anno
2023
Pagine
926
ISBN
9783031266805
200,00 €

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Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. With an estimated 80% of people with diabetes living in disadvantaged regions, and the key roles of lipoproteins in the pathogenesis of the chronic complications of diabetes, this volume will be relevant to many readers globally. It is our intention that the contents will advance knowledge of the readers who will use it to contribute to the reduction of the burden associated with altered lipoproteins in people with diabetes. 

 

The second edition of this book provides an updated and comprehensive review of the field. The book, which includes many tables and figures, is presented in three main sections: (i) Lipoprotein metabolism, qualitative changes and measurements; (ii) Lipoproteins and the complications of diabetes; and (iii) the treatment of lipoproteins in diabetes. Each chapter from the first edition has been updated, and new topics added. New topics include the links between glycemia and lipoproteins, the role of lipoproteins in ischemic stroke, the diagnosis and management of statin intolerance (which is thought to be more common in people with diabetes) and the use of PCSK9 inhibitors and fish oils in the management of lipoproteins in people with diabetes.  This book is written by an international group of experts in the clinical, laboratory and research aspects of lipoproteins in diabetes.

 

Lipoproteins in Diabetes Mellitus, 2nd Edition is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It is a must-have resource for primary care and specialist clinicians, clinical and basic science researchers and to trainees and students.

  1. Front Matter

    Pages i-xx

    PDF

  2. Lipoprotein Metabolism, Qualitative Changes and Measurements

    1. Front Matter

      Pages 1-1

      PDF

    2. Laboratory Assessment of Lipoproteins in Type 2 Diabetes

      • David R. Sullivan

      Pages 3-15

    3. Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus

      • Richard L. Klein, Andrea J. Semler, Alicia J. Jenkins

      Pages 17-31

    4. Links Between Glucose and Lipoproteins

      • Alicia J. Jenkins

      Pages 33-54

    5. Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes

      • Thomas D. Dayspring, Peter P. Toth

      Pages 55-109

    6. Lipoprotein Metabolism and Alterations Induced by Insulin Resistance and Diabetes

      • Gerald H. Tomkin, Daphne Owens

      Pages 111-143

    7. The PPAR System in Diabetes

      • Jean Claude Ansquer

      Pages 145-167

    8. Production and Metabolism of Triglyceride-Rich Lipoproteins: Impact of Diabetes

      • Angela Pirillo, Giuseppe D. Norata, Alberico L. Catapano

      Pages 169-194

    9. Triglyceride- and Cholesterol-Rich Remnant Lipoproteins in Risk of Cardiovascular Disease in Diabetes Mellitus

      • Benjamin Nilsson Wadström, Anders Berg Wulff, Kasper Mønsted Pedersen, Børge Grønne Nordestgaard

      Pages 195-222

    10. HDL Function in Diabetes

      • Anna Gluba-Brzózka, Magdalena Rysz-Górzyńska, Jacek Rysz

      Pages 223-245

    11. Lipoprotein(a): Metabolism, Pathophysiology, and Impact on Diabetes Mellitus

      • Karam Kostner, Gerhard M. Kostner

      Pages 247-274

    12. Lipoprotein Glycation in Diabetes Mellitus

      • Alicia J. Jenkins, Richard L. Klein, Andrea J. Semler, Andrzej S. Januszewski

      Pages 275-318

    13. Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes

      • Danielle Kamato, Peter J. Little

      Pages 319-336

  3. Lipoproteins and the Complications of Diabetes

    1. Front Matter

      Pages 337-337

      PDF

    2. The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes

      • Maria F. Lopes-Virella, Gabriel Virella

      Pages 339-355

    3. Endothelial Dysfunction in Type 2 Diabetes with an Update on New Interventions

      • Natalie C. Ward, Wann Jia Loh, Gerald F. Watts

      Pages 357-406

    4. Lipoproteins and Diabetic Kidney Disease

      • Fanny Jansson Sigfrids, Nina Elonen, Per-Henrik Groop

      Pages 407-438

    5. Lipids and Diabetic Retinopathy

      • Alicia J. Jenkins

      Pages 439-464

    6. Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy

      • Timothy J. Lyons

      Pages 465-484

      1. The Role of Lipids and Lipoproteins in Peripheral Neuropathy

        • Juan D. Collazos-Alemán, María P. Salazar-Ocampo, Carlos O. Mendivil

        Pages 485-502

      2. Lipoproteins and Ischemic Stroke in Diabetes

        • Renato Quispe, Michael Goestch, Brigitte Kazzi, Fawzi Zghyer, Arielle Abovich, Steven Zeiler et al.

        Pages 503-522

    7. Lipoprotein Treatment in Diabetes

      1. Front Matter

        Pages 523-523

        PDF

      2. About Randomized Clinical Trials Related to Lipoproteins in Diabetes Mellitus

        • Anthony Keech, Alicia J. Jenkins, Val Gebski, Ian Marschner

        Pages 525-553

      3. Effects of Lifestyle (Diet, Plant Sterols, Exercise, and Smoking) and Glycemic Control on Lipoproteins in Diabetes

        • Peter Clifton

        Pages 555-577

      4. Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Patients with Diabetes

        • Brent M. Gudenkauf, Steven R. Jones, Seth S. Martin

        Pages 579-595

      5. Statin Intolerance: An Overview for Clinicians

        • Stanisław Surma, Joanna Lewek, Peter E. Penson, Maciej Banach

        Pages 597-635

      6. Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Patients with Diabetes Mellitus Type 2

        • Eliot A. Brinton, Vishnu Priya Pulipati

        Pages 637-679

      7. EPA and Mixed Omega-3 Fatty Acids: Impact on Dyslipidemia and Cardiovascular Events in Patients with Diabetes

        • Om P. Ganda, Robert Busch, J. R. Nelson, Sephy Philip

        Pages 681-704

      8. Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid-Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus

        • Harold Edward Bays

        Pages 705-734

      9. Clinical Efficacy of Proprotein Convertase Synthase Kexin Type 9 Inhibition in Persons with Diabetes Mellitus

        • Peter P. Toth, Manfredi Rizzo, Maciej Banach

        Pages 735-753

      10. Clinical Care of Lipids in People with Type 1 Diabetes

        • Nick S. R. Lan, Alicia J. Jenkins, P. Gerry Fegan

        Pages 755-778

      11. Adjunct Drug Treatment to Reduce Vascular Disease in People with Diabetes

        • Alicia J. Jenkins

        Pages 779-819

      12. Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes

        • Alex Bobik, Neale Cohen, Alicia J. Jenkins, Tin Kyaw, David Sullivan, Xiaoqian Wu et al.

        Pages 821-878

    8. Epidemiology of Diabetes and Diabetic Dyslipidemia

      1. Front Matter

        Pages 879-879

        PDF

      2. Diabetes Epidemiology and Its Implications

        • Zachary Bloomgarden, Yehuda Handelsman

        Pages 881-890

      3. Epidemiology, Control, and Cardiovascular Outcomes of Dyslipidemia in Diabetes

        • Wenjun Fan, Nathan D. Wong

        Pages 891-913

    9. Back Matter

      Pages 915-926

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