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Epidemiology of Renal Cell Carcinoma
Pages 3-16
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
Epidemiology of Renal Cell Carcinoma
Pages 3-16
Pathologic Considerations
Pages 17-30
Molecular Biology of Kidney Cancer
Pages 31-57
Biomarkers for Renal Cell Carcinoma
Pages 59-82
Genetic Heterogeneity of Kidney Cancer
Pages 83-88
The Metabolic Basis of Kidney Cancer
Pages 89-102
Renal Cell Carcinoma: Clinical Presentation, Staging, and Prognostic Factors
Pages 105-121
Hereditary Kidney Cancer Syndromes
Pages 123-133
Surgical Approaches to Early-Stage Renal Cell Carcinoma
Pages 137-156
Cytoreductive Nephrectomy
Pages 157-171
Metastasectomy
Pages 173-194
Thermal Ablative Techniques in Renal Cell Carcinoma
Pages 195-215
The Role of Radiation Therapy in Renal Cell Carcinoma
Pages 217-225
Adjuvant Systemic Therapy for Renal Cell Carcinoma
Pages 229-243
Cytokines in the Management of Advanced Renal Cell Cancer
Pages 245-258
Immune Checkpoint Inhibition in Renal Cell Carcinoma
Pages 259-279
Angiogenesis Inhibitor Therapy in Renal Cell Cancer
Pages 281-294
The Role of mTOR Inhibitors and PI3K Pathway Blockade in Renal Cell Cancer
Pages 295-314
Combinatorial and Sequential Targeted Therapy in Metastatic Renal Cell Carcinoma
Pages 315-334
Presurgical Therapy in Renal Cell Carcinoma
Pages 335-343
Variant Renal Carcinoma Histologies: Therapeutic Considerations
Pages 345-364
Toxicity Management of Renal Cell Cancer Patients on Targeted Therapies
Pages 365-384
Emerging Agents in Renal Cell Carcinoma
Pages 385-402
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