VOLUME 1
Section 1
PROCEDURES,TECHNIQUES AND ULTRASONOGRAPHY
Stephen O. Heard and Michael Hill
Chapter 1 Point-of-Care Critical Care Ultrasono
graphy
Paul H. Mayo, Seth J. Koenig, and Gisela I. Banauch
Anesthesia for Bedside Procedures
Gregory J. Mitchon and Mark Dershwitz
Management of Pain in the Critically Ill
1
Chapter 2
4
Chapter 3
11
Alexandra Chang and Mario De Pinto
Chapter 4
Therapeutic Paralysis
22
Khaldoun Faris
Chapter 5
Cerebrospinal Fluid Aspiration
29
Marcey Osgood, Gisela I. Banauch, and Paul H. Mayo
Chapter 6
Central Venous Catheters
38
Or Bruck, Scott E. Kopec, and Craig M. Lilly
Chapter 7
Arterial Line Placement and Care
54
Siddhartha S. Narayanan, Scott E. Kopec, and Michael Hill
Chapter 8
Airway Management and Endotracheal Intubation
J. Aaron Scott, J. Matthias Walz, and Stephen O. Heard
64
Chapter 9
Tracheostomy
82
Christine L. Bielick Kotkowsk, Scott E. Kopec, Rahul N. Sood, Paul H. Mayo,
and Seth J. Koenig
Chapter 10
Bronchoscopy
91
Rahul N. Sood, Marie Mullen, Paulo J. Oliveira, and Richard S. Irwin
Chapter 11
Lung Ultrasonography
97
Fiore Mastroianni, Andrew G. Weber, and Paul H. Mayo
Chapter 12
Thoracentesis
102
Gisela I. Banauch, Seth J. Koenig, Paul H. Mayo, Mark M. Wilson,
Richard S. Irwin, and Craig M. Lilly
Chapter 13
Chest Tube Insertion and Care
111
Ulises Torres, Ryan J. Hendrix, and Seth J. Koenig

Chapter 14
Cardiopulmonary Resuscitation
119
Viral Patel and Michael Hill
Chapter 15
Cardioversion and Defibrillation
135
Glenn T. Stokken and Mark Link
Chapter 16
Critical Care Echocardiography
Zubair Hasan, Paul H. Mayo, and Craig M. Lilly
140
Chapter 17
Pericardiocentesis
146
Patrick J. Abt, Ruo Chen, Seth J. Koenig, and Craig S. Smith
Chapter 18
Temporary Cardiac Pacing
Glenn T. Stokken and Basel Edris
Pulmonary Artery Catheters
Catherine M. Kuza and Harvey S. Reich
155
Chapter 19
161
Chapter 20
Gastrointestinal Endoscopy
176
Christopher A. Marshall
Chapter 21
Endoscopic Placement of Feeding Tubes
Lena M. Napolitano, Paul H. Mayo, and Seth J. Koenig
183
Chapter 22
Gastroesophageal Balloon Tamponade for Acute Variceal
Hemorrhage
190
Robert Canelli, Hamza Durrani, and Marie T. Pavini
Chapter 23
Paracentesis and Diagnostic Peritoneal Lavage
Lena M. Napolitano, Paul H. Mayo, Seth J. Koenig, and Marisa Smith
Interventional Radiology: Percutaneous Drainage Techniques
195
Chapter 24
204
Alex Newbury and Aaron L. Harman
Chapter 25
Percutaneous Suprapubic Cystostomy
212
Philip J. Ayvazian
Chapter 26
Aspiration of the Knee and Synovial Fluid Analysis
Yevgeniy Popov, Deborah M. Demarco, Karen Salomon-Escoto,
and Francisco De La Serna
216
Section 2
MINIMALLY INVASIVE MONITORING
Todd W. Sarge
Chapter 27 Routine Monitorin
g of Critically Ill Patients
222
Matthew R. Stutz and Krysta S. Wolfe
Chapter 28
Minimally Invasive Hemodynamic Monitoring
Nihar Shah, Brad Petkovich, Atul Malhotra, and Andrew J. Goodwin
Respiratory Monitoring During Mechanical Ventilation
Alison Trainor, Leonid Rabkin, Todd W. Sarge, and Elias Baedorf Kassis
236
Chapter 29
248
Chapter 30
Neurologic Multimodal Monitoring
Raphael A. Carandang and Wiley R. Hall
261
Chapter 31
Role of Tele-Critical Care in the Health Care System
279
David W. Guidry, William Beninati, Lloyd Meeks, Shahzad Shaefi, and Craig M. Lilly
Section 3
PALLIATIVE CARE AND ETHICAL ISSUES IN THE INTENSIVE CARE UNIT
Jennifer Reidy
Chapter 32 Palliative Care in the ICU
288
Dana Lustbader, Mangala Narasimhan, Nandita R. Nadig, and Dee W. Ford
Chapter 33
Effective Communication and Ethical Decision-Making in the ICU 293
Daniel E. Ray, Christine E. Lau, and Jennifer E. Allen

Chapter 34
Managing Symptoms in Critically Ill Patients
Jennifer Reidy, Elizabeth Manzo, and Richard Castriotta
308
Chapter 35
Being With Suffering: Addressing Existential and Spiritual Distress 321
Margaret Isaac, Suzana K. E. Makowski, and Christina Fitch
Section 4
SHOCK,TRAUMA AND SEPSIS MANAGEMENT
Jon D. Dorfman
Chapter 36 Resuscitation From Shock F
ollowing Hemorrhage
Jacob A. Quick, Alison A. Smith, Donald H. Jenkins, John B. Holcomb,
Stephen L. Barnes, and Seth J. Koenig
328
Chapter 37
Trauma Systems
341
Vishnu Mani, Ioana Antonescu, and Suresh Mitu Agarwal
Chapter 38
Management of Sepsis
347
Ioana Antonescu, Vishnu Mani, and Suresh Mitu Agarwal
Chapter 39
Multiple Organ Dysfunction Syndrome
Andrew C. Bernard and Timothy A. Pritts
358
Chapter 40
Traumatic Brain Injury
363
Raphael A. Carandang and Wiley R. Hall
Chapter 41
Spinal Cord Trauma
371
Ryan M. Schiedo, Hanbing Zhou, and Christian P. Dipaola
Chapter 42
Thoracic and Cardiac Trauma
381
Bruce J. Simon, Scott B. Johnson, and John G. Myers
Chapter 43
Critical Care of the Patient With Abdominal Trauma
394
Jon D. Dorfman
Chapter 44
Orthopedic Injury
402
Sravya T. Challa, Vivek Venugopal, and John J. Wixted
Chapter 45
Burn Management
417
Naveen F. Sangji, Sean Figy, Joyce K. Mcintyre, and Mark R. Hemmila
Section 5
SURGICAL PROBLEMS IN THE INTENSIVE CARE UNIT
Jennifer LaFemina
Chapter 46 Surgeon and Intensivist Collabor
ation in the Care of
the ICU Patient
Gustavo G. Angaramo, Bushra Abdul Aleem, and Craig M. Lilly
Surgical Infections in the Intensive Care Unit
Suraj Panjwani, Ann-Kristin U. Friedrich, and Mitchell Cahan
423
Chapter 47
427
Chapter 48
Care of the Patient with Necrotizing Fasciitis
430
Bankole Samuel, Chloe H. Williams, Brandon Colvin, and Hongyi Cui
Chapter 49
The ICU Management of Patients Undergoing Major Surgery for
Gastrointestinal Cancers
435
Kate H. Dinh, Ricardo J. Bello, and Jennifer Lafemina
Chapter 50
The ICU Approach to the Acute Abdomen
440
James E. Carroll Jr and Nicole B. Cherng
Chapter 51
Abdominal Compartment Syndrome
444
Jon D. Dorfman and Clark R. Murray

Chapter 52
Management of the Obstetrical Patient in the Intensive
Care Setting
448
Anne Garrison
Chapter 53
Acute Limb Ischemia in the ICU Population
Dejah R. Judelson, Bing Shue, and William P. Robinson III
454
Chapter 54
Palliative Surgery in the Intensive Care Unit
459
Laura A. Lambert and Sarah Childs
Section 6
TRANSPLANTATION
Stephanie M. Levine
Chapter 55 M
anagement of the Organ Donor
467
Christoph Troppmann
Chapter 56
Critical Care Problems in Kidney Recipients
Elizabeth L. Godfrey, Abbas A. Rana, and Rainer W.G. Gruessner
Critical Care of Liver Transplant Recipients and
Live Liver Donors
Han Li, Paulo N. Martins, Nicole M. Theodoropoulos, and Babak Movahedi
Critical Care of the Lung Transplant Recipient
Jake G. Natalini, Luis F. Angel, and Stephanie M. Levine
Critical Care Problems in Heart and Heart-Lung
Transplant Recipients
Matthew Soule, Rishav Aggarwal, and Sara J. Shumway
Care of the Pancreas Transplant Recipient
Colleen L. Jay, Robert J. Stratta, Alan Farney, Jeffrey Rogers,
and Giuseppe Orlando
Critical Care of Intestinal Transplant Recipients
Robert M. Esterl Jr, Ruy J. Cruz Jr, and Abhinav Humar
Immunosuppression in Solid-Organ Transplantation
Hasan Al-Harakeh, Bishoy Emmanuel, Sundaram Hariharan,
Abhinav Humar, and Martin N. Wijkstrom
491
Chapter 57
501
Chapter 58
515
Chapter 59
530
Chapter 60
538
Chapter 61
553
Chapter 62
562
Chapter 63
Hematopoietic Cell Transplantation
569
Ann E. Woolfrey, Masumi Ueda Oshima, Marco Mielcarek,
and Paul A. Carpenter
Chapter 64
Management of Graft-vs-Host Disease, Infection, Malignancy,
and Rejection in Transplant Recipients
Elizabeth L. Godfrey, Adrish Anand, Vaughn E. Whittaker, Abbas A. Rana,
David L. Dunn, and Rainer W. G. Gruessner
586
Section 7
RHEUMATOLOGIC, IMMUNOLOGIC,AND DERMATOLOGIC DISEASES IN
THE INTENSIVE CARE UNIT
Paul F. Dellaripa
Chapter 65 Rheumatologic Diseases in the Intensive Care Unit
606
Elena Gkrouzman and Nancy Y. N. Liu
Chapter 66
Vasculitis in the Intensive Care Unit
Paul F. Dellaripa and Donough Howard
631

Chapter 67
Therapeutics in Immune-Mediated Rheumatic Diseases
639
Ilirjana Duka and Peggy Wu
Chapter 68
Anaphylaxis
648
Priya Katari and Frederic F. Little
Chapter 69
Dermatology in the Intensive Care Unit
661
Bina Kassamali, Nathaniel Goldman, Kristen G. Berrebi, Dori Goldberg,
Mary E. Maloney, and Avery H. Lachance
Section 8
INFECTIOUS DISEASE PROBLEMS IN THE INTENSIVE CARE UNIT
Nicole M. Theodoropoulos
Chapter 70 Approach to Fever for the ICU Patient
683
Raul E. Davaro and Richard H. Glew
Chapter 71
Prevention and Control of Health Care–Acquired Infections
in the Intensive Care Unit
690
Sumanth Gandra and Richard T. Ellison III
Chapter 72
Use of Antimicrobials in the Treatment of Infection in the
Critically Ill Patient
697
Mohmmad Hajjiri, Richard H. Glew, and Jennifer S. Daly
Chapter 73
Life-Threatening Community-Acquired Bacterial
and Parasitic Infections
713
Samuel L. Windham and Misha Huang
Chapter 74
Acute Infection in the Non–HIV-Infected
Immunocompromised Host
722
Nicole M. Theodoropoulos, Robert W. Finberg, and Jennifer S. Daly
Chapter 75
Intensive Care of Patients With HIV Infection
Thomas C. Greenough and Juan M. Perez Velazquez
732
Chapter 76
Infectious Complications of Persons Who Inject Drugs
740
Muhammad Dhanani and Kinna Thakarar
Chapter 77
Infective Endocarditis and Infections of Intracardiac
Prosthetic Devices
746
John Raymond Go, Larry M. Baddour, and Raj Palraj
Chapter 78
Infections Associated With Vascular Catheters
768
Payal K. Patel and Suzanne F. Bradley
Chapter 79
Urinary Tract Infections
775
Aalok V. Khole and George M. Abraham
Chapter 80
Central Nervous System Infections
785
Michael Haden and Shandra R. Day
Chapter 81
Tuberculosis
796
Michelle K. Haas and Robert W. Belknap
Chapter 82
Serious Epidemic Viral Pneumonias
804
Hannah Nam, Christopher M. Coleman, Daniel Libraty, and Michael Ison
Chapter 83
COVID-19: Presentation,Treatment, and Course of Severe
Acute Respiratory Syndrome Coronavirus 2 Infection in
the Intensive Care Unit
815
Magdalena Slosar-Cheah and Robert W. Finberg†
Chapter 84
Critical Care of Patients Infected With Ebola Virus
822
Steven Hatch

Chapter 85
Botulism
826
David M. Bebinger and Richard T. Ellison III
Chapter 86
Tetanus
829
Mary Dawn T. Co and Richard T. Ellison III
Section 9
HEMATOLOGIC AND ONCOLOGIC PROBLEMS IN THE INTENSIVE CARE UNIT
Jonathan Gerber
Chapter 87 Disorders of Hemostasis in Critically Ill Patients
832
Shrinkhala Khanna, Kathleen Sargent, and Alice D. Ma
Chapter 88
Transfusion Therapy: Blood Components and Transfusion
Complications
Yong (David) Zhao, Terry B. Gernsheimer, and Vishesh Chhibber
848
Chapter 89
Anemia in the Critical Care Setting
856
Carol M. Mathew, Marc S. Zumberg, and Marc J. Kahn
Chapter 90
Thrombocytopenia
Thomas G. Deloughery
871
Chapter 91
Venous Thromboembolism and Associated Prothrombotic
Disorders in the Intensive Care Unit
882
Kathryn A. F. Kline and Jennie Y. Law
Chapter 92
Antithrombotic Pharmacotherapy
906
Kevin E. Anger, Jeremy R. Degrado, and John Fanikos
Chapter 93
Critical Care of Patients with Hematologic Malignancies
928
Matthew J. Wieduwilt and Lloyd E. Damon
Chapter 94
Oncologic Emergencies
940
Shyam A. Patel, Andrew Gillis-Smith, and Sakiko Suzuki
Chapter 95
Therapeutic Apheresis: Technical Considerations and
Indications in Critical Care
952
Laura S. Connelly-Smith
Section 10
PHARMACOLOGY, OVERDOSES AND POISONINGS
Luke Yip and Mark J. Neavyn
Chapter 96 General Considerations in the E
valuation
and Treatment of Poisoning
Morgan A. A. Riggan, Major Colin Laverty, and Ian M. Ball
964
Chapter 97
Acetaminophen Poisoning
981
Steven B. Bird
Chapter 98
Alcohols and Glycol Poisoning
Jennifer L. Englund and Marco L. A. Sivilotti
989
Chapter 99
Amphetamines
1004
Michael C. Beuhler
Chapter 100 Antiarrhythmic Agents
Steven B. Bird and Brian L. Mcquaide
Chapter 101 Anticholinergic Poisoning
Keith K. Burkhart
Chapter 102 Anticonvulsant Poisoning
1011
1021
1024

Chapter 103 Antidepressant Poisoning
1033
Varun Vohra, Cynthia Aaron, and Mark J. Neavyn
Chapter 104 Antipsychotic Poisoning
1045
Steven B. Bird
β-Blocker Poisoning
Chapter 105
1056
Shan Yin and Javier C. Waksman
Chapter 106 Calcium Channel Blocker Poisoning
Christopher R. Dewitt and Maude St-Onge
Chapter 107 Cardiac Glycoside Poisoning
1060
1067
Brian G. Lewis and Bryan S. Judge
Chapter 108 Cholinergic Poisoning
1071
Brandtly Yakey, Andrew King, and Cynthia Aaron
Chapter 109 Cocaine Poisoning
1077
Richard D. Shih and Judd E. Hollander
Chapter 110 Corrosives Poisoning
Kennon Heard
Chapter 111 Heavy Metal Poisoning
1083
1088
Laurie Seidel Halmo and Luke Yip
Chapter 112 Hydrocarbon Poisoning
William J. Lewander and Alfred Aleguas
Chapter 113 Hydrofluoric Acid Poisoning
1102
1108
Kennon Heard
Chapter 114 Iron Poisoning
Milton Tenenbein
Chapter 115 Isoniazid Poisoning
1110
1115
James B. Mowry, Greene Shepherd, and Adam G. Overberg
Chapter 116 Lithium Poisoning
1119
Thanjira Jiranantakan and Kent R. Olson
Chapter 117 Methylxanthine Poisoning
1124
Janetta L Iwanicki
Chapter 118 Opioid Poisoning
1131
Stephanie T. Weiss and Luke Yip
Chapter 119 Pesticide-Herbicide Poisoning
1140
William K. Chiang and Richard Y. Wang
Chapter 120 Phencyclidine and Hallucinogen Poisoning
Jennie A. Buchanan and Luke Yip
Chapter 121 Salicylate and Other Nonsteroidal Anti-inflammatory
Drug Poisoning
1154
1161
Henry D. Swoboda and Marco L. A. Sivilotti
Chapter 122 Sedative-Hypnotic Agent Poisoning
1169
Andis Graudins and Dino Druda
Chapter 123 Terrestrial Envenomations
1177
Dalia Alwasiyah and Michael C. Beuhler
Chapter 124 Therapeutic Agents for Overdoses and Poisonings
1190
Laurie Seidel Halmo, Susan E. Gorman, Jerry D. Thomas, and Luke Yip
Chapter 125 Withdrawal Syndromes
1210
Ashley Haynes and Paul M. Wax

VOLUME 2
Section 11
CRITICAL CARE CONSEQUENCES OF WEAPONS (AGENTS) OF MASS DESTRUCTION
Lawrence C. Mohr
Chapter 126 Planning and Organization for Emergency Mass Critical Care 1222
Ryan C. Maves and Mary A. King
Chapter 127 Chemical Agents of Mass Destruction 1229
James Geiling, Randy S. Wax, and Lawrence C. Mohr
Chapter 128 The Management of Acute Radiation Casualties 1239
Riyaa M. Rekha, Arvind K. Sundaram, Mary Jane Reed, John Scott Parrish,
James Geiling, and Lawrence C. Mohr
Chapter 129 Critical Care Consequences of Weapons (or Agents) of Mass
Destruction—Biological Agents of Mass Destruction 1249
Ryan C. Maves, Bhavita J. Gaglani, Charles G. Volk, and Konrad L. Davis
Section 12
ICU DESIGN, ORGANIZATION, OPERATION AND OUTCOME MEASURES
Neil A. Halpern
Chapter 130 Intensive Care Unit Design: Current Standards and
Future Trends
Neil A. Halpern, Lilly A. Bothwell, and Diana C. Anderson
Chapter 131 Intensive Care Unit Organization and Management
Mark A. Tidswell, Bogdan Tiru, and Thomas L. Higgins
Chapter 132 Critical Care Information Systems (Systems of Engagement
and Insight): Structure, Function, and Future
1273
1285
1295
Joseph J. Frassica and Vitaly Herasevich
Chapter 133 Defining and Measuring Patient Safety in the Critical Care Unit 1305
Sahil Kumar Virdi, Hayley B. Gershengorn, Steven Y. Chang, David E. Ost,
Kelly L. Cervellione, and Alan M. Fein
Chapter 134 Assessing the Impact of Critical Care: Outcomes Research
and Methodologies in the Current Era 1314
Anica C. Law, May Hua, Nandita R. Nadig, and Kelly C. Vranas
Chapter 135 Blockchain Technology and Medical Device Security in
the Intensive Care Unit 1325
Chris Landon, Ted Dellavecchia, John R. Zaleski, and Neil A. Halpern
Section 13
ENDOCRINE PROBLEMS IN THE INTENSIVE CARE UNIT
Neil Aronin and David M. Harlan
Chapter 136 Management of Hyperglycemia in Critically Ill Patients
Asem H. Ali, Vrushali H. Shah, David M. Harlan, and Leslie J. Domalik
Chapter 137 Diabetic Comas: Ketoacidosis and Hyperosmolar
Hyperglycemic State
1330
1338
Leslie J. Domalik, Vrushali H. Shah, David M Harlan, and Asem H. Ali
Chapter 138 Hypoglycemia
1350
John P. Mordes, Michael J. Thompson, David M. Harlan, and Samir Malkani

Chapter 139 Hypoadrenal Crisis and the Stress Management of
the Patient on Chronic Steroid Therapy
1365
Eyad Hamoudeh and Neil Aronin
Chapter 140 Disorders of Mineral Metabolism
Seth M. Arum and Gabriela Szabo
Chapter 141 Severe Hyperthyroidism
1368
1375
Marjorie S. Safran
Chapter 142 Myxedema Coma
1378
Mira Sofia Torres, Charles H. Emerson, and Craig M. Lilly
Chapter 143 Nonthyroidal Illness Syndrome (Sick Euthyroid Syndrome)
in the Intensive Care Unit
1382
Shirin Haddady and Alan P. Farwell
Section 14
NEUROLOGIC PROBLEMS IN THE INTENSIVE CARE UNIT
Wiley R. Hall
Chapter 144 An Approach to Neurologic Problems in
the Intensive Care Unit
1397
Wiley R. Hall
Chapter 145 Evaluating the Patient With Altered Consciousness in the
Intensive Care Unit
1400
Raphael A. Carandang and Lawrence J. Hayward
Chapter 146 Metabolic Encephalopathy
1416
Alaaedin Alhomosh
Chapter 147 Mental Status Dysfunction in the Intensive Care Unit:
Postoperative Cognitive Impairment
Andrew M. Galica, Elizabeth R. Degrush, and Joan M. Swearer
Chapter 148 Generalized Anoxia/Ischemia of the Nervous System
1424
1429
Banu Sundar and Majaz Moonis
Chapter 149 Cerebrovascular Diseases
1432
Richard P. Goddeau Jr and Majaz Moonis
Chapter 150 Subarachnoid Hemorrhage
1443
Alaaedin Alhomosh
Chapter 151 Status Epilepticus
1449
Kyle C. Rossi and Felicia C. Chu
Chapter 152 Guillain-Barré Syndrome
1457
Isabelita R. Bella and David A. Chad
Chapter 153 Myasthenia Gravis in the Intensive Care Unit
Isabelita R. Bella and Lan Qin
Chapter 154 Newly Acquired Weakness in the Intensive Care Unit:
Critical Illness Myopathy and Neuropathy
Mehdi Ghasemi and David A. Chad
Chapter 155 Neuro-oncological Problems in the Intensive Care Unit
N. Scott Litofsky and Kia Ghiassi
Chapter 156 Miscellaneous Neurological Problems in the Intensive
Care Unit
1467
1475
1479
1491
Max Ruben Mandelbaum

Section 15
PSYCHIATRIC ISSUES IN THE INTENSIVE CARE UNIT
Patrick Smallwood
Chapter 157 Diagnosis and Treatment of Agitation and Delirium in
the Intensive Care Unit Patient
Curtis A. Mcknight and Jason P. Caplan
Chapter 158 Diagnosis and Treatment of Anxiety in the Intensive
Care Unit Patient
Shelley A. Holmer and Robert M. Tighe
Chapter 159 Diagnosis and Treatment of Depression in the Intensive
Care Unit Patient
Cezar I. Cimpeanu, Meghan S. Kolodziej, and Theodore A. Stern
Chapter 160 Managing the Suicidal Patient in the Intensive Care Unit
Christina N. Massey and Saori A. Murakami
Chapter 161 Problematic Behaviors of Patients, Family, and Staff in the
Intensive Care Unit
Craigan Usher
Chapter 162 Recognition and Management of Staff Stress in the
Intensive Care Unit
1499
1508
1516
1534
1537
1543
Guy Maytal
Section 16
PULMONARY PROBLEMS IN THE INTENSIVE CARE UNIT
J. Mark Madison
Chapter 163 Acute Respiratory Failure Due to Acute Respiratory Distress
Syndrome and Pulmonary Edema
Maryellen C. Antkowiak and Gilman B. Allen
Chapter 164 Acute Respiratory Failure in Pregnancy
Felicia Chen and Christine Campbell-Reardon
Chapter 165 Extrapulmonary Causes of Respiratory Failure
Mark M. Wilson and Richard S. Irwin
Chapter 166 Invasive Mechanical Ventilation and Extracorporeal Life
support for Respiratory Failure
Rolando Sanchez and Gregory A. Schmidt
Chapter 167 Mechanical Ventilation—Part II: Noninvasive Mechanical
Ventilation for the Adult Hospitalized Patient
1548
1566
1582
1593
1611
Anas A. Ahmed and Nicholas S. Hill
Chapter 168 Discontinuation of Mechanical Ventilation
Nicholas A. Smyrnios and Richard S. Irwin
Chapter 169 Respiratory Adjunctive Therapies
1629
1639
Christine L. Bielick Kotkowski, Scott E. Kopec, and Richard S. Irwin
Chapter 170 Aspiration
1654
Natasha Dudiki, Kimberly A. Robinson, and Richard S. Irwin
Chapter 171 Drowning
1660
Nicholas A. Smyrnios and Richard S. Irwin
Chapter 172 Acute Exacerbation of Asthma
1666
Kathryn Waksmundzki-Silva, Richard S. Irwin, and J. Mark Madison

Chapter 173 Critical Care of Acute Exacerbations of Chronic Obstructive
Pulmonary Disease
Shameek Gayen, Mark Weir, and Gerard J. Criner
Chapter 174 Pulmonary Hypertension in the Intensive Care Unit
1679
1687
Kimberly A. Fisher, Jonathan D. Holdorf, and Harrison W. Farber
Chapter 175 Managing Hemoptysis
1694
Paulo J. Oliveira, Shahzad W. Khan, and Richard S. Irwin
Chapter 176 Pleural Diseases of the Critically Ill Patient
1704
John Terrill Huggins, Amit Chopra, and Peter Doelken
Chapter 177 Gas Embolism Syndromes
Kyle T. Halligan and Mark M. Wilson
Chapter 178 Acute Inhalational Injuries
1720
1733
Anna Nolan, Sophia Kwon, Michael D. Weiden, Lawrence C. Mohr,
and David J. Prezant
Chapter 179 Chest Radiographic Examination
1750
Carole A. Ridge, Nidhish Jeyin, Benedikt H. Heidinger,
and Diana E. Litmanovich
Chapter 180 Severe Upper Airway Infections
1772
William W. Wong, Stephen J. Krinzman, Evan W. Jones, and Richard S. Irwin
Chapter 181 Acute Infectious Pneumonia
1786
Girish B. Nair and Michael S. Niederman
Chapter 182 Interventional Pulmonary in the Intensive Care Unit
Chris S. Yan, Rahul N. Sood, Andres F. Sosa, and Paulo J. Oliveira
Chapter 183 Sleep Issues in the Intensive Care Unit Setting
Biren B. Kamdar, Erica B. Feldman, and Nancy A. Collop
Chapter 184 Disorders of Temperature Control, Part I: Hypothermia
Marcia Kathryn Steiner, Hannah Murphy, and Richard S. Irwin
Chapter 185 Disorders of Temperature Control, Part II: Hyperthermia
1814
1828
1840
1854
Marcia Kathryn Steiner, Hannah Murphy, and Richard S. Irwin
Section 17
CARDIOVASCULAR PROBLEMS AND CORONARY CARE
David A. Morrow and Akshay S. Desai
Chapter 186 Evolution of the Modern Cardiovascular Intensive Care Unit
Hannah F. Bensimhon and Jason N. Katz
Chapter 187 Unstable Angina/Non–ST-Segment Elevation Myocardial
Infarction, the Non–ST-Elevation Acute Coronary Syndromes
Nicholas A. Marston and Marc S. Sabatine
Chapter 188 ST-Segment Elevation Myocardial Infarction
Christopher B. Fordyce and David A. Morrow
Chapter 189 Mechanical Complications of Myocardial Infarction
Mohamed A. Omer, Jacob C. Jentzer, and Emmanouil S. Brilakis
Chapter 190 Management of Acute Decompensated Heart Failure
Zachary L. Cox and Jeffrey M. Testani
Chapter 191 Pharmacological Management of Shock and Hypotension
Michael M. Givertz and James C. Fang
Chapter 192 Mechanical Circulatory Support for Cardiogenic Shock
1867
1872
1886
1904
1911
1924
1940
Ajar Kochar and Erin A. Bohula

Chapter 193 Valvular Heart Disease
1958
Yee-Ping Sun, Garrick C. Stewart and Patrick T. O’Gara
Chapter 194 Acute Aortic Syndromes
1976
Marc P. Bonaca and T. Brett Reece
Chapter 195 Management of the Cardiac Arrest Survivor
Michael G. Silverman and Benjamin M. Scirica
Chapter 196 Management of Common Arrhythmias in the
Intensive Care Unit
Thomas M. Tadros and William H. Sauer
Chapter 197 Management of Cardiac Devices in the ICU
1994
2004
2021
Melanie Maytin
Section 18
RENAL PROBLEMS IN THE INTENSIVE CARE UNIT
Pang-Yen Fan
Chapter 198 Metabolic Acidosis and Metabolic Alkalosis
Jason M. Kurland and Ashfaq Balla
Chapter 199 Disorders of Plasma Sodium and Plasma Potassium
Amar Pandit, Eric Lida and Kenneth Ralto
Chapter 200 Acute Kidney Injury in the Intensive Care Unit
Konstantin Abramov and Jahan Montague
Chapter 201 Renal Replacement Therapy for the Critically Ill
Matthew Niemi, Matthew Joseph Trainor, and Ari Nalbandian
Chapter 202 Ultrasonography for the Evaluation of the Urinary System
Paul H. Mayo, Seth J. Koenig, Satya Allaparthi, K. C. Balaji, Philip J. Ayvazian,
and Craig M. Lilly
Chapter 203 Drug Dosing in Renal and Hepatic Failure: A Pharmacokinetic
Approach to the Critically Ill Patient
2033
2044
2069
2092
2106
2109
Irene Li, Peter S. Golenia, Nicholas A. Servati, Mackenzie Piché, Neil P. Wallis,
and Renu Nathan
Section 19
GASTROINTESTINAL DISEASE PROBLEMS IN THE INTENSIVE CARE UNIT
C. Prakash Gyawali
Chapter 204 Gastrointestinal Bleeding
2130
Surachai Amornsawadwattana, Michael C. Bennett, C. Prakash Gyawali,
and Chien-Huan Chen
Chapter 205 Stress Ulcer and Acid Peptic Disease
2138
Benjamin E. Cassell, Ami Y. Patel, C. Prakash Gyawali, and Amit Patel
Chapter 206 Nausea and Vomiting
2144
Angelica G. Nocerino, Md and Henry P. Parkman, Md
Chapter 207 Gastrointestinal Motility of the Critically Ill Patient
2153
Benjamin Rogers, Anthony J. Lembo, and C. Prakash Gyawali
Chapter 208 Hepatic Dysfunction and Liver Failure
Avegail G. Flores and Mauricio Lisker-Melman
Chapter 209 Severe and Complicated Biliary Tract Disease
2160
2171
Tarek Abou Hamdan and Riad Azar

Chapter 210 Acute Pancreatitis
2176
Ingrid B. Schwartz, Krunal Patel, Wahid Y. Wassef, and Rajesh N. Keswani
Chapter 211 Diarrhea and Constipation
2185
Daniela Guerrero Vinsard and Laura Harrell Raffals
Chapter 212 Fulminant Colitis and Toxic Megacolon
2193
Emanuelle A. Bellaguarda and Stephen B. Hanauer
Section 20
METABOLISM AND NUTRITION
Ulises Torres
Chapter 213 Nutritional Therapy in the Critically Ill Patient
2199
Ulises Torres
Chapter 214 Parenteral and Enteral Nutrition in the Intensive Care Unit
2204
Katherine L. Saunders and Ulises Torres
Chapter 215 Disease-Specific Nutrition
2219
Paul J. Foster, Michelle Rightmyer, Jessica Lundberg, and Alexis P. Calloway
Appendix
CALCULATIONS COMMONLY USED IN CRITICAL CARE
2231
Joseph J. Frassica
Index