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The first practical guide for hospitalists on the use of anticoagulants in hospitalized patients
This edited volume provides a comprehensive overview of the vital topic of anticoagulation in the hospital setting. Designed specifically for use by hospital-based clinicians and associated hospital-based staff, this fully evidence-based book addresses the most commonly used anticoagulant agents, the latest advances in anticoagulation drugs, and primary indications for their use at therapeutic levels.
This thorough, easy-to-use reference summarizes the most important guidelines and medical literature on anticoagulation. It features a careful review of the epidemiology and treatment of complications associated with anticoagulants. Unique topics include transition of care and practical strategies for developing and implementing quality improvement programs to enhance the administration and safety of anticoagulants.
This concise resource also covers:
Antiplatelet medications
The treatment and prevention of venous thromboembolism in medical patients
Venous thromboembolism prophylaxis in surgical patients
Peri-operative management of oral anticoagulants and antiplatelet agents
Prevention of cardioembolic stroke
Antithrombotics for ischemic stroke
Antithrombotic therapy for non-ST elevation acute coronary syndrome
Hemorrhagic complications of anticoagulants in hospitalized patients
Heparin-induced thrombocytopenia
Hospitalists and other members of the patient care team will find that Inpatient Anticoagulation answers their questions with dependable and timely information.
Contributors ix
1. Pharmacology of Parenteral Anticoagulants 1
Kathleen H. McCool and Daniel M. Witt
2. Pharmacology of Vitamin K Antagonists 25
Jaekyu Shin and Steven R. Kayser
3. Antiplatelet Medications 47
Michael Kornfeld and Joseph R. Munsayac
4. Newer Oral Anticoagulants 67
Taki Galanis and Geno J. Merli
5. Prevention of Venous Thromboembolism in Medical Patients 81
Alex C. Spyropoulos and Charles E. Mahan
6. Prevention of Venous Thromboembolism in Surgical Patients 107
Nancy Torres Finnerty and Franklin Michota
7. Treatment of Acute Venous Thromboembolism in Hospitalized Patients 137
Tracy Minichiello, Lauren Doctoroff, and Elizabeth A. Farrell
8. Perioperative Management of Oral Anticoagulants and Antiplatelet Agents 161
Ramiro Jervis and Andrew Dunn
9. Prevention of Cardioembolic Stroke 179
Ali Mahajerin and Warren J. Manning
10. Antithrombotics for Ischemic Stroke 205
Fadi B. Nahab and Sakib Qureshi
11. Antithrombotic Therapy for Non-ST-Elevation Acute Coronary Syndrome 223
David Lao and Andrew Boyle
12. Parenteral Anticoagulants: Special Considerations in Patients with Chronic Kidney Disease and Obesity 241
Sarah A. Spinler, Millie Rajyaguru, Julie K. Atay, and John Fanikos
13. Hemorrhagic Complications of Anticoagulants in Hospitalized Patients 291
Allison Burnett, Jason Cohen, and David A. Garcia
14. Heparin-Induced Thrombocytopenia 331
David Feinbloom and John Fani Srour
15. Transitions in Care: Inpatient Anticoagulation 361
Neil Gupta, Diane Sliwka, and Margaret C. Fang
16. Optimizing Inpatient Anticoagulation: Strategies for Quality Improvement 377
Greg Maynard, Ian Jenkins, Brian Clay, Michael Montazeri, and Doug Humber
Index 415
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