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Definition of IPF
Pages 3-9
From epidemiology and pathogenesis to disease management, this book reviews our current understanding of and provides up-to-date information of Idiopathic Pulmonary Fibrosis (IPF). A subtype of Idiopathic Interstitial Pneumonias (IIP), IPF is one of the most elusive and intractable respiratory disease to date and its triggering factors remain unclear. However, new developments such as serum markers that are highly specific to IPF (i.e. KL-6, SP-A, and SP-D), the establishment of systematic diagnostic imaging (HRCT) and accumulated reports of treatment using an antifibrotic agent (pirfenidone) are slowly improving our understanding of the disease. Edited by an established authority in the field and written by experts, this book will be valuable to not only to beginning learners but also to physicians, instructors and researchers whose work involves IIPs. With each chapter exploring critical questions, with unresolved issues and future prospects, the book offers a valuable resource for understanding issues such as the newly proposed entity of interstitial pneumonia with emphysema (combined pulmonary fibrosis and emphysema: CPFE) and the mechanism of how so many IIP sufferers develop lung cancer.
Definition of IPF
Pages 3-9
Epidemiology and Risk Factors of IPF
Pages 11-25
Acute Exacerbation of IPF
Pages 27-42
Pathogenesis of IPF
Pages 43-58
Specific Serum Markers of IPF
Pages 61-76
High-Resolution Computed Tomography of Honeycombing and IPF/UIP
Pages 77-104
Pathology of IPF
Pages 105-132
Differential Diagnosis of IPF
Pages 133-144
Pharmacotherapy of IPF Using Antifibrotic Compounds
Pages 147-159
Pharmacotherapy of IPF (Corticosteroids, Immunosuppressants, Etc.)
Pages 161-170
Non-pharmacological Therapy for IPF
Pages 171-188
Pharmacotherapy of Acute Exacerbation of IPF (Corticosteroids, Immunosuppressants, and Direct Hemoperfusion with Polymyxin)
Pages 189-201
Combined Pulmonary Fibrosis and Emphysema (CPFE)
Pages 205-215
Common Pathways in IPF and Lung Cancer
Pages 217-247
Acute Exacerbation of Interstitial Pneumonia After Pulmonary Resection for Lung Cancer
Pages 249-259
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