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Hypertrophic Cardiomyopathy
Foreword by Bernard Gersh and Historical Context by Eugene Braunwald
Naidu
Editore
Springer
Anno
2015
Pagine
321
ISBN
9781447149552
120,00 €
I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.
  • About this book

  • An up-to-date and comprehensive reference on Hypertrophic Cardiomyopathy written by experts in the field of this increasingly important area in cardiology
  • Concentrates on the multi-disciplinary and longitudinal nature of the disease and provide evidence-based solutions for management where available
  • “Key points” for each chapter, as well as “tips and tricks”, will help the reader understand the nuances of this disease that have not previously been disseminated to the wider community

This book provides a comprehensive clinical review of Hypertrophic Cardiomyopathy (HCM), the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level, resulting in the development of abnormal and occasionally focal hypertrophy on a macroscopic level.

Editor, Srihari S. Naidu, has brought together a world renowned group of experts to review various different topics but, with a practical focus that will enable readers to establish the evidence-based best practice in any potential scenario. Treatment modalities including medications, pacemakers and defibrillators, and invasive septal reduction therapy (both surgical myectomy and alcohol septal ablation) will be discussed. Chapters on genetics, family screening, lifestyle concerns, and athletic screening have additionally been added given the ongoing controversies and differences of opinion on many of these issues. 

Each chapter within Hypertrophic Cardiomyopathy begins with key points of knowledge and ends with clinical pearls that have not previously been disseminated to the wider community. The practical approach of the entire book continues with dedicated chapters on creating a Center of Excellence, including how to facilitate the multi-disciplinary approach, and on case-based reviews and discussions allowing readers to further understand how to integrate the knowledge gained from each chapter into the comprehensive and longitudinal care of the individual patient and family. The last chapter takes the reader through the management of actual patients, showing over decades the nuances to diagnosis and management and the sometimes abrupt changes in the course of their diseases that necessitate correspondingly abrupt modifications in treatment. 

This book will be an essential text for Trainees, Fellows, Residents and board-certified physicians in cardiology, interventional cardiology, cardiac surgery, cardiac imaging, sports medicine, paediatric cardiology, genetics and genetic counselling, and electrophysiology.

Table of Contents

1 Hypertrophic Cardiomyopathy: The Past, the Present, and the Future . . . . . 1
Eugene Braunwald
2 Natural History of Untreated Hypertrophic Cardiomyopathy . . . . . . . . . . . . . 9
Qin Li , Lynne Williams, and Harry Rakowski
3 Pathology and Pathophysiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
Kazuyuki Yahagi , Elena Ladich, and Renu Virmani
4 Approach to Diagnosis: Echocardiography. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Beevash Ray and Matthew W. Martinez
5 Cardiac MRI in Diagnosis and Management . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
Jonathan Kahan , Juan Gaztanaga, and Mario Jorge Garcia
6 Genetics of HCM and Role of Genetic Testing . . . . . . . . . . . . . . . . . . . . . . . . . . 77
Christopher Semsarian and Jodie Ingles
7 Assessment of Heart Failure: Invasive and Non-invasive Methods. . . . . . . . . . 85
Michael A. Fifer and Aaron L. Baggish
8 Assessment of Syncope . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97
Nickolaos Michelakis and Todd J. Cohen
9 Pediatric Diagnosis and Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107
Steven D. Colan
10 Sudden Cardiac Death Risk Assessment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
Katy E. Bockstall , Michael P. Gannon , Weijia Wang, and Mark S. Link
11 Youth and Athletic Screening: Rationale, Methods and Outcome . . . . . . . . . . 133
David S. Owens and Sanjay Sharma
12 Lifestyle Modifi cation: Diet, Exercise, Sports and Other Issues . . . . . . . . . . . . 143
David S. Owens
13 Family Screening: Who, When and How. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155
Michelle Michels and Folkert J. ten Cate
14 Medical Therapy: From Beta–Blockers to Disopyramide . . . . . . . . . . . . . . . . . 165
Keith Mankowitz
15 Indications and Outcome of PPM and ICD Placement . . . . . . . . . . . . . . . . . . . 179
Joseph J. Germano , Joshua R. DeLeon , Daniel R. Zakhary,
and Mark E. Josephson
16 Management of Arrhythmia: Medications, Electrophysiology
Studies and Ablation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193
Daniel R. Zakhary , Joseph J. Germano, and Mark E. Josephson

17 Indications for and Individualization of Septal Reduction Therapy . . . . . . . . 207
Dmitriy N. Feldman , John S. Douglas Jr., and Srihari S. Naidu
18 Surgical Myectomy and Associated Procedures: Techniques
and Outcomes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223
Sandhya K. Balaram and Daniel G. Swistel
19 Alcohol Septal Ablation: Technique and Outcome. . . . . . . . . . . . . . . . . . . . . . . 237
Paul Sorajja
20 End-Stage Diastolic and Systolic Heart Failure:
Evaluation and Timing of Heart Transplantation . . . . . . . . . . . . . . . . . . . . . . . 247
Eric D. Popjes , Anjali Tiku Owens, and Mariell Jessup
21 Approach to the Initial and Follow-Up Visits . . . . . . . . . . . . . . . . . . . . . . . . . . . 255
Paolo Spirito and Camillo Autore
22 Evaluation and Management of Hypertrophic Cardiomyopathic
Patients Through Noncardiac Surgery and Pregnancy . . . . . . . . . . . . . . . . . . . 269
Nadia B. Hensley and Theodore P. Abraham
23 Constructing a Hypertrophic Cardiomyopathy Center of Excellence . . . . . . . 279
B. Robinson Williams III
24 Longitudinal Case Based Presentations in HCM . . . . . . . . . . . . . . . . . . . . . . . . 287
Abdul Moiz Hafi z , Jonathan A. Elias , Kanika P. Mody ,
Jenna Kahn, and Srihari S. Naidu
 

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