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Hormone Therapy and Castration Resistance of Prostate Cancer
Arai, Ogawa
Editore
Springer
Anno
2018
Pagine
433
ISBN
9789811070129
150,00 €

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This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged.

During the last decade, much evidence on hormone therapy has been accumulated in Japan. Interestingly, some of these findings are different from those reported from Western countries, suggesting ethnic variation in the outcome of hormone therapy. In the chapters of this book, expert authors provide exhaustive interpretations of the evidence recently reported from Japan and provide important Asian perspectives on hormone therapy for PCa. This work benefits not only Asian urologists but also their Western counterparts and all physicians and medical personnel who are involved in the treatment of PCa.

Table of contents (43 chapters)

 
  • Introduction

    Arai, Yoichi (et al.)

    Pages 1-2

  • Recent Trends in Hormone Therapy for Prostate Cancer in Japan

    Onozawa, Mizuki (et al.)

    Pages 3-11

  • Risk Assessment Among Patients Receiving Primary ADT for Prostate Cancer

    Hinotsu, Shiro, M.D.

    Pages 13-18

  • Patient-Derived Xenografts for Research on Hormonal Therapy of Prostate Cancer

    Inoue, Takahiro, M.D., Ph.D.

    Pages 19-30

  • Impact of GnRH Antagonist and LHRH Agonist on the Gonadal Axis

    Miyazawa, Yoshiyuki (et al.)

    Pages 31-40

  • Controversies on Combined Androgen Blockade for Prostate Cancer

    Mizokami, Atsushi, M.D., Ph.D.

    Pages 41-50

  • Adrenal Androgen in Prostate Cancer

    Shibata, Yasuhiro

    Pages 51-58

  • Intermittent ADT for Prostate Cancer

    Akakura, Koichiro

    Pages 59-67

  • Prognostic Significance of Monitoring Serum Testosterone in Primary ADT for Prostate Cancer

    Sakamoto, Shinichi

    Pages 69-75

  • Ethnic Variation in Clinical Outcomes of Hormone Therapy for Prostate Cancer

    Fukagai, Takashi, M.D., Ph.D. (et al.)

    Pages 77-88

  • Androgen Deprivation Therapy in Combination with Radical Prostatectomy

    Koie, Takuya (et al.)

    Pages 89-97

  • ADT in Combination with Radiation Therapy for Clinically Localized Prostate Cancer

    Mizowaki, Takashi, M.D. Ph.D.

    Pages 99-112

  • ADT as Salvage Therapy After Definitive Treatment for Clinically Localized Prostate Cancer

    Yokomizo, Akira

    Pages 113-119

  • Androgen Deprivation Therapy for Clinically Localized Prostate Cancer

    Arai, Yoichi, M.D., Ph.D. (et al.)

    Pages 121-131

  • Complications of ADT for Prostate Cancer: Hot Flashes

    Sakai, Hideki (et al.)

    Pages 133-139

  • Complications of ADT for Prostate Cancer: Osteoporosis and the Risk of Fracture

    Uemura, Hiroji, M.D., Ph.D

    Pages 141-150

  • Metabolic Health for Patients with Prostate Cancer During Androgen Deprivation Therapy

    Mitsuzuka, Koji (et al.)

    Pages 151-164

  • Bone Scan Index as a Biomarker of Bone Metastasis

    Nakajima, Kenichi (et al.)

    Pages 165-174

  • Genetic Polymorphism Analysis in Predicting Prognosis of Advanced Prostate Cancer

    Tsuchiya, Norihiko

    Pages 175-187

  • Local Therapy in Combination with Androgen Deprivation Therapy for Metastatic Prostate Cancer

    Tsumura, Hideyasu, M.D. (et al.)

    Pages 189-199

  • Oxidative Stress and Castration-Resistant Prostate Cancer

    Shiota, Masaki, M.D., Ph.D.

    Pages 201-214

  • Alternative Antiandrogen Therapy for CRPC

    Utsumi, Takanobu (et al.)

    Pages 215-223

  • Optimization of Sequential AR Targeted Therapy for CRPC

    Terada, Naoki, M.D., Ph.D.

    Pages 225-229

  • Enzalutamide Therapy for mCRPC in Japanese Men

    Kimura, Go

    Pages 231-239

  • Abiraterone Acetate Therapy for mCRPC in Japanese Men

    Ikeda, Masaomi, M.D., Ph.D. (et al.)

    Pages 241-247

  • Role of Estramustine Phosphate and Other Estrogens for Castration-Resistant Prostate Cancer

    Inoue, Takahiro, M.D., Ph.D.

    Pages 249-256

  • Corticosteroid Therapy for CRPC

    Nishimura, Kazuo

    Pages 257-266

  • microRNA Analysis in Prostate Cancer

    Enokida, Hideki, M.D., Ph.D.

    Pages 267-291

  • AR Splice Variant in Prostate Cancer

    Yamashita, Shinichi (et al.)

    Pages 293-298

  • Detection of Circulating Tumor Cells in Castration-Resistant Prostate Cancer

    Okegawa, Takatsugu, M.D.

    Pages 299-305

  • New Biomarker for Castration-Resistant Prostate Cancer: A Glycobiological Perspective

    Hatakeyama, Shingo, M.D. (et al.)

    Pages 307-315

  • Bone-Targeted Treatment in CRPC Management

    Kamba, Tomomi, M.D., Ph.D.

    Pages 317-325

  • Skeletal Complications in Patients with CRPC

    Inoue, Takamitsu, M.D. (et al.)

    Pages 327-338

  • Urological Complications in Men Dying from Prostate Cancer

    Kobayashi, Takashi, M.D., Ph.D.

    Pages 339-344

  • Prediction of Optimal Number of Cycles in Docetaxel Regimen for Patients with mCRPC

    Matsuyama, Hideyasu (et al.)

    Pages 345-355

  • Intermittent Chemotherapy with Docetaxel for Metastatic Castration-Resistant Prostate Cancer

    Narita, Shintaro, M.D. (et al.)

    Pages 357-368

  • Chemotherapy with Cabazitaxel for mCRPC in Japanese Men

    Nozawa, Masahiro (et al.)

    Pages 369-373

  • New Targeted Approach to CRPC

    Kosaka, Takeo, M.D., Ph.D. (et al.)

    Pages 375-385

  • Molecular Basis of Neuroendocrine Prostate Cancer

    Akamatsu, Shusuke

    Pages 387-396

  • Gene Therapy for Prostate Cancer: Current Status and Future Prospects

    Nasu, Yasutomo (et al.)

    Pages 397-406

  • Immune Therapy for Castration-Resistant Prostate Cancer

    Yoshimura, Kazuhiro, M.D., Ph.D. (et al.)

    Pages 407-418

  • A New Approach to Castration-Resistant Prostate Cancer Using Inactivated Virus

    Fujita, Kazutoshi (et al.)

    Pages 419-425

  • Patient-Reported Outcome in the Management of CRPC

    Matsubara, Nobuaki, M.D.

    Pages 427-433

 

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